Device for concentration of bioparticles for identification comprises one or more capillary flow paths from at least one inlet for advection along the path of bioparticles in a buffer solution, two or more membranes along the flow path, the membranes being individually selectable for electrical powering, thereby to controllably set up a powered membrane region at a location along said path, said powered membrane region causing localized concentration of the bioparticles, digital-like manipulation of the preconcentrated bioparticles plugs, and detection surface immobilized molecular probes located along said flow path to detect the bioparticles following localized concentration.

Provided is a detection method for heavy metal ions that includes the following steps. A waste water is flowed through an ion-imprinted polymer tube for adsorbing at least two kinds of target heavy metal ions. The ion-imprinted polymer tube is rinsed to remove a non-target object from the ion-imprinted polymer tube. The target heavy metal ions in the ion-imprinted polymer tube are desorbed by using an acid liquid. An electrochemical method is performed to detect concentrations of the target heavy metal ions.

A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2 to 25 compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.

An electromembrane extraction (EME) device including a union connector, an acceptor compartment with a connector end and a donor compartment with a connector end wherein both connector ends are connectable to the union connector, wherein the union connector includes a flat membrane with a seal on each side thereof, wherein the seals when the acceptor compartment and the donor compartment are connected to the union connector are arranged respectively between the acceptor compartment connector end and the flat membrane and the donor compartment connector end and the flat membrane.

Disclosed are methods, compositions, and devices for an integrated, heterogenerous ion-exchange membrane-based plastic microfluidic biochip platform that can be used to detect multiple diagnostic markers present in real samples. Its various components can be easily integrated in a modular fashion for different applications. Automated control allows sequential and dynamic activation of different components on the chip. The integrated platform consists of three units and is designed to execute the following functions: (i) separation of the target biomolecules from the real sample, (ii) localizing and concentrating the targeted molecules at a specific location in the microfluidic chip, and (iii) detection of the targeted molecules using hybridization/docking events against a complementary ssDNA oligoprobe sequence or a specific antibody.

A method and system for measuring the content of dissolved organic halide in water. The method includes separating dissolved inorganic halides and dissolved organic halides in water using an electrodialysis technique (S1), which may completely separate the dissolved organic halides and the dissolved inorganic halides, avoid the use of activated carbon and adsorption columns, simplify steps and improve efficiency. The method converts the separated dissolved organic halides into dissolved inorganic halides using a photocatalysis technique (S2), which does not need a special high-temperature combustion device, active carbon and catalysts, and is simple and easy to be performed at room temperature in more environmentally friendly mode. The method also includes analyzing the converted dissolved inorganic halides using a device with an ion analysis function (S3) to analyze and measure a total content index of the dissolved organic halides and an individual content index of each of the dissolved organic halides (fluorine, chlorine, bromine and iodine) in water to be measured.

A kit for extracting mycotoxin residues in agricultural products according to the present disclosure includes a pipe, a first powder mixture layer and a second powder mixture layer. The pipe has an output port at the bottom thereof and an input port at the top thereof for inputting a sample solution. The first powder mixture layer is in the form of powder and filled in the pipe. The first powder mixture layer contains cation exchange resin powder, C18 and diatomaceous earth powder. The second powder mixture layer is in the form of powder and filled in the pipe. The second powder mixture layer is located below the first powder mixture layer and above the output port. The second powder mixture layer contains PSA powder, anhydrous magnesium sulfate powder, activated carbon, PLS powder, diatomaceous earth powder and C18 powder. The present disclosure further provides a method of obtaining a primary test liquid from agricultural products using the above kit.

Systems and methods are described to concentrate a remote sample for analysis. A sample concentration system embodiment includes, but is not limited to, a plurality of valves including at least a first valve, a second valve, and a third valve; a plurality of columns including at least a first column and a second column, the first column fluidically coupled to the first valve, the second column fluidically coupled to the second valve; and a flow meter coupled with the third valve, the flow meter fluidically coupled with each of the first column and the second column when the plurality of valves is in a first flow path configuration to measure an amount of the liquid sample passed through the first column and the second column, wherein the plurality of valves includes a second flow path configuration and a third flow path configuration.

Described are methods for detecting and quantifying biomolecules such as polynucleotides or polypeptides in an electrophoresis matrix using ion concentration polarization and nanoparticle aggregation.

An electromembrane extraction (EME) device including a union connector, an acceptor compartment with a connector end and a donor compartment with a connector end wherein both connector ends are connectable to the union connector, wherein the union connector includes a flat membrane with a seal on each side thereof, wherein the seals when the acceptor compartment and the donor compartment are connected to the union connector are arranged respectively between the acceptor compartment connector end and the flat membrane and the donor compartment connector end and the flat membrane.