Detection omission is reduced. An optical measuring device according to an embodiment includes: a plurality of excitation light sources (32A to 32D) that irradiates a plurality of positions on a flow path through which a specimen flows with excitation rays having different wavelengths; and a solid-state imaging device (34) that receives a plurality of fluorescent rays emitted from the specimen passing through each of the plurality of positions, in which the solid-state imaging device includes: a pixel array unit (91) in which a plurality of pixels is arrayed in a matrix; and a plurality of first detection circuits (93) connected to a plurality of pixels not adjacent to each other in the same column of the pixel array unit, respectively.

A system for detecting biological particles includes a dilution apparatus and a selectively capturing apparatus. The dilution apparatus includes a microfluidic channel, a sample tray assembly, and a first optical detection module. The microfluidic channel is connected to a sample reservoir adapted to supply sample containing the target biological particles. The sample tray assembly includes a sample tray for containing sample discharged through the microfluidic channel. The first optical detection module provides a first optical pathway passing through the microfluidic channel. When the target biological particles that flow through the microfluidic channel are detected by the first optical detection module, the sample tray assembly provides the sample tray for loading the target biological particles that flow through the microfluidic channel. The sample tray containing the target biological particles is moved to the selectively capturing apparatus. After a second optical detection module locates an accurate position of each of the target biological particles on the sample tray, the capturing device is moved to the accurate position of each of the target biological particles to capture the target biological particles into a collection plate.

A cell observation system observes a cell moving in a flow path with a fluid, and includes a first observation apparatus, a second observation apparatus, and a control device. The first observation apparatus includes an objective lens and a line camera. The second observation apparatus includes an objective lens and an area camera. The control device analyzes first imaging data output from the first observation apparatus to determine whether the cell satisfies a specific condition, instructs the area camera to output second imaging data of the cell determined to satisfy the specific condition, and analyzes the second imaging data output from the second observation apparatus to determine whether the cell is a specific cell.

A measurement system includes a system for causing relative motion between a sample and an irradiation spot. The sample includes fluorescent markers having respective wavelengths. A gating system provides a gating signal based at least in part on resultant light substantially at an irradiation wavelength. A detection system detects fluorescent light from the irradiated markers and provides detection signals representing the fluorescent light detected concurrently with a gate-open signal. In some examples, the detection system detects fluorescent light at multiple wavelengths and provides respective detection signals. A spectral discriminator arranged optically between the sample and the detection system receives the fluorescent light from the sample and provides respective fluorescent light at the wavelengths to the detection system. A flow cytometer can spectrally disperse resultant fluorescent light and measure the wavelengths separately. Light from a sample disposed over a reflective phase grating can be dispersed, measured, and gated.

The present technology provides a technology for stabilizing break-off timings. Therefore, according to the present technology, there is provided a microparticle analysis device or the like including at least: a flow path in which a fluid including a sample flow containing microparticles and a sheath flow flowing to contain the sample flow; a droplet formation unit configured to form a droplet in the fluid by imparting vibration to the fluid using a vibration element; an electric charge application unit configured to apply electric charge to a droplet containing the microparticles; an imaging unit configured to obtain a photo of a phase of a certain time; and a control unit configured to control a timing at which the droplet breaks off on a basis of the photo.

An optical particle sensor comprises at least first and second light sources of different wavelength for sequential operation. An optical detector is used to detect light from the light sources emitted or scattered by particles to be sensed. A current injection compensation signal is also provided which is dependent on which light source of the optical arrangement is in use. The compensation signal means the amplifier does not need to re-settle in response to different background illumination levels associated with the different light sources. In this way, detection signals may be obtained in quick succession from different light sources.

An apparatus for sorting cells includes a measurement volume that contains a cell to be measured, a light source that provides light to cause an emission by a fluorescent label attached to the cell, and an optic device that directs the light through the measurement volume. The apparatus flows the cells through the measurement volume such that as the cell flows through the measurement volume, it interacts with the light, resulting in a change in light originating from the measurement volume, the change in light is a fluorescence emission. Another optic device directs a portion of the light originating from the measurement volume to a detector, which detects the portion of the light. A processor operably coupled to the detector generates an estimate of DNA quantity in the cell based on the change in light originating from the measurement volume, and determines a characteristic of the cell from the estimate.

Disclosed herein are a particle sorting device capable of simply detecting bubbles, foreign substances, or the like in droplets, a method for analyzing particles, a program, and a particle sorting system. The particle sorting device includes a judgment unit, and the judgment unit judges whether or not captured image information including captured droplet image information about a brightness of an image of particle-containing droplets captured after discharge from an orifice has changed with respect to previously-set reference image information including reference droplet image information about a brightness of an image of droplets captured after discharge from the orifice.

A apparatus for detecting cells or particles in a fluid container includes a dispenser configured to dispense at least one cell or at least one particle into a defined sub-volume of a fluid with which the fluid container is at least partially filled, and a detection apparatus configured to, in a time-coordinated manner with dispensing the at least one cell or the at least one particle by the dispenser, perform a detection in the defined sub-volume and/or in one or several sub-volumes underneath the defined sub-volume in order to sense the at least one cell or the at least one particle when entering the fluid or immediately after entering the fluid.

The present invention provides an apparatus for analyzing particles in a solution including a unit configured to place a flow cell having a flow path for flowing a sample solution containing the particles; a unit configured to illuminate the sample solution flowing through the flow path of the flow cell; a photodetector that detects a scattered light and/or fluorescence generated from the particles in the sample solution; and a unit configured to analyze the particles based on their signal intensities detected by the photodetector, wherein the flow cell has the flow path formed in a substrate, a reflection plane is formed on the side surface of the flow path, the reflection plane leads the lights generated in the flow path of the flow cell and advancing in the substrate in-plane direction to a specified region of the surface of the flow cell, and the photodetector detects the light exiting from the specified region to the outside.