The present invention provides a sensing device for detecting an analyte containing a non-metallic element such as F. A working sensor has a 3D array of voids each having a void internal wall. The void internal walls have cavities each having a cavity internal wall made from a material containing the non-metallic element. A binding of the analytes to the cavities induces a detectable variation of the optical property of the 3D array of voids. The invention exhibits numerous technical merits such as high sensitivity, high specificity, fast detection, ease of operation, low power consumption, zero chemical release, and low operation cost, among others.

The present invention provides a novel and efficient process of preparing a highly organized 3D array of particles by stacking multiple 2D arrays of the particles. The 3D array of particles so prepared is used in fabrication of sensors, such as molecular imprinted photonic (MIP) crystal sensor. The sensor has a 3D array of voids each having a void internal wall. The void internal walls have cavities each having a cavity internal wall made from a material containing the non-metallic element. A binding of the analytes to the cavities induces a detectable variation of the optical property of the 3D array of voids. The invention exhibits numerous technical merits such as high sensitivity, high specificity, fast detection, ease of operation, low power consumption, zero chemical release, and low operation cost, among others.

An optical element includes a porous layer with a network of a plurality of interconnected voids. The porous layer is optically diffusive to at least one wavelength of light when the network of interconnected voids is substantially free of fluid. The porous layer of the optical element undergoes a detectable optical change upon fluid ingress into the network or egress from the network of interconnected voids.

The present invention relates to an optoelectronic device (1) for detection of a target substance dispersed in a fluid (50). The optoelectronic device comprises:a light source (2) adapted to emit a light radiation (L.sub.E) having an adjustable wavelength .sub.S;an integrated electronic circuit (100) comprising a photonic circuit (10) operatively coupled to said light source;a control unit (9) operatively coupled to said light source and to said photonic circuit.

The present invention provides a dual grating sensor having at least two double-sided grating structures for detecting the properties of an analyte. The dual grating sensor includes a substrate, a waveguide layer which is formed on the substrate and has at least two double-sided grating structures, and an upper cover configured on the waveguide layer, wherein a channel is formed between the upper cover and the waveguide layer for the analyte to flow therethrough. A light couples into the waveguide layer via the first double-sided grating structure, transmits in the waveguide layer, and couples out of the waveguide layer via the second double-sided grating structure, such that the properties of the analyte can be detected according to the change of the light intensities of the emergent light. The sensitivity of the dual grating sensor has an additive effect when the light passes through the first double-sided grating structure and the second double-sided grating structure.

A method and system for measuring a sample property (X) by means of photonic circuit (10). The photonic circuit (10) comprises at least two photonic sensors (11, 12) configured to modulate the light according to respective output signals (S1,S2) with periodically recurring signal values (V1, V2). The photonic sensors (11, 12) comprise a low range sensor (11) with a relatively low range or high sensitivity for measuring a change (X) of the sample property (X) and a high range sensor (12) with a relatively high range or low sensitivity to measure the change (X) of the sample property (X). The sample property (X) is calculated by combining the output signals (S1, S2) of the sensors (11, 12). Particularly, the second output signal (S2) of the high range sensor (12) is used to distinguish between recurring signal values (V1) in the first output signal (S1) of the low range sensor (11).

A planar waveguide device (PWD) for interacting with a fluid (FLD) is disclosed, the planar waveguide device (PWD) comprising a waveguide layer (WGL) for supporting optical confinement, a coupling arrangement (CPA) for in-coupling and out-coupling of light into and from the waveguide layer (WGL), a fluid zone (FZN) for accommodating the fluid (FLD), a filter layer (FTL) arranged between the fluid zone (FZN) and the waveguide layer (WGL) in an interaction region (IAR) of the waveguide layer (WGL),
wherein the filter layer (FTL) comprises filter openings (FOP) arranged to allow the fluid (FLD) to interact with an evanescent field of light guided by the waveguide layer (WGL),
wherein the filter openings (FOP) are adapted to prevent particles (PAR) larger than a predefined size from interacting with said evanescent field,
wherein the filter openings (FOP) are arranged as line openings having their longitudinal direction in parallel with the direction of propagation (DOP) of light guided by the waveguide layer (WGL).

The present disclosure is to provide a measurement chip, a measuring device, and a measuring method which can accurately estimate an analyte concentration with a simple configuration. A measurement chip may include a propagation layer, an introductory part, a drawn-out part and a reaction part. Through the propagation layer, light may propagate. The introductory part may introduce the light into the propagation layer. The drawn-out part may draw the light from the propagation layer. The reaction part may have, in a surface of the propagation layer where a reactant that reacts to a substance to be detected is formed, an area where a content of the reactant changes monotonously in a perpendicular direction perpendicular to a propagating direction of the light, over a given length in the propagating direction.

The present invention provides a dual grating sensor having at least two double-sided grating structures for detecting the properties of an analyte. The dual grating sensor includes a substrate, a waveguide layer which is formed on the substrate and has at least two double-sided grating structures, and an upper cover configured on the waveguide layer, wherein a channel is formed between the upper cover and the waveguide layer for the analyte to flow therethrough. A light couples into the waveguide layer via the first double-sided grating structure, transmits in the waveguide layer, and couples out of the waveguide layer via the second double-sided grating structure, such that the properties of the analyte can be detected according to the change of the light intensities of the emergent light. The sensitivity of the dual grating sensor has an additive effect when the light passes through the first double-sided grating structure and the second double-sided grating structure.

Devices and methods of providing a high-performance optical sensor disclose a sensor comprised of a porous material designed to have a multilayer rib-type or multilayer pillar-type waveguide geometry. The resulting porous nanomaterial multilayer-rib or multilayer-pillar waveguide design is optically capable of achieving 100% confinement factor while maintaining small mode area and single-mode character. Fabrication of the device is enabled by an inverse processing technique, wherein silicon wafers are first patterned and etched through well-established techniques, which allows porous nanomaterial synthesis (i.e., porous silicon anodization) either at the wafer-scale or at the chip-scale after wafer dicing. While 100% is an optimal target, typical devices per presently disclosed subject matter may operate with 98-99+%, while allowing for some design adjustments to be made if necessary, and still maintaining high sensitivity. i.e., >85-90% confinement suitable in some applications. In those instances, a primary benefit would still be use of the presently disclosed fabrication technology.