A semiconductor device according to the present invention includes a substrate, a plurality of electrodes on the substrate, an insulator provided with one or a plurality of openings exposing at least one electrode among the plurality of electrodes on the substrate, the insulator covering at least a portion of the plurality of electrodes, and a semiconductor sheet on the insulator and one or a plurality of exposed portions exposed from the one or the plurality of openings on the substrate.

Provided are methods of manufacturing comprising providing a FET base structure, the FET base structure comprising a substrate, a drain and a source; and providing a channel layer on the FET base structure; and providing a first layer on the FET base structure. The first layer comprises a one-dimensional or two-dimensional material and is arranged on an upper surface of the channel layer so as to form a sensing surface of the FET. The step of providing the channel layer comprises forming the channel layer and subsequently transferring the channel layer onto the FET base structure. Alternatively or additionally, the step of providing the first layer on the FET base structure comprises forming the first layer and subsequently transferring the first layer onto the FET base structure.

The present disclosure describes methods of detecting viral biomolecules such as viruses through frequency response. A method (200) of detecting a vims includes exposing (210) a sensor surface to a fluid sample containing a suspected virus. The sensor surface can be a surface of a resonator having a clean resonant frequency from about 1 MHz to about 1 GHz. The surface can be modified with molecular recognition groups selective for binding to the viral biomolecule. A resonant frequency of the resonator can be measured (220) after exposing the sensor surface to the fluid sample. The measured resonant frequency can be compared (230) with a clean resonant frequency indicating the presence of the viral biomolecule bound to the molecular recognition groups and then outputted (240) as a detection signal.

Provided are devices and methods for detecting a target molecule, based on using a graphene electrode. The devices exhibit high sensitivity to target molecules such as DNA that may be present at comparatively low concentrations.

A Fano resonator device can be used to sequence DNA or other macromolecules. The device includes customized molecular components, informed by computation analysis. Techniques for preparing and using the device also are disclosed. The device can be incorporated in a system that further includes a sample processing component and a flow chamber.

A method of detecting an analyte in a fluid sample includes exposing a sensor including a substrate and a sensor medium on the substrate to the fluid sample for a period of time. The sensor medium includes a plurality of nanostructures and one or more of at least one agent selected from the group consisting of an antibody, an antigen receptor or an antigen immobilized upon at least a portion of the plurality of nanostructures. The at least one agent is an antibody or an antigen receptor if the analyte is an antigen and is an antigen if the analyte is an antibody. An electrolyte liquid having a known ionic strength which is less than the fluid sample is added over the sensor medium subsequent to exposing the sensor to the fluid and a variable providing a measure of change in at least one property of the sensor medium which is dependent upon the presence of the analyte is measured in presence of the electrolyte liquid.

A chemical sensor for detecting a target substance in a gas sample, including a membrane; and an olfactory receptor fragment which is fixed to the membrane. The chemical sensor optionally includes a source electrode connected to one end of the membrane; and a drain electrode connected to the other end of the membrane, in which the membrane is a graphene.

A precision graphene nanoribbon (GNR) bridge molecule can include: a central GNR having a precision structure selected the following structural types: armchair, zigzag, cove, chevron, and fjord; a functional anchoring group at either end of the GNR selected from the following: amine, thiol, thioether, stannane, halide, boronic acid, boronic ester, azide, and carbene; a central functional conjugation group at a precisely specified location; and edge group functionalization with solubilizing groups selected from the following: linear and branched alkyl chains, substituted aromatic rings, oligoethylene glycol, carboxylic acids, and sulfonic acids.

A semiconductor device includes a first gate electrode, a first insulating unit, a source electrode, a drain electrode, and a contact part. The first insulating unit is provided on a second gate electrode configured to control a reference voltage in a transport characteristic. The source electrode is connected to the first insulating unit. The drain electrode is connected to the first insulating unit. The contact part is provided between the source electrode and the drain electrode on the first insulating unit, and being able to be in contact with a sample. The sample is able to be in contact with the first gate electrode. A surface opposite to the first insulating unit, of the contact part is configured to be in contact with the samp1e.

A bioelectronic sensor is disclosed for detecting presence of at least one volatile organic compound (VOC), the sensor comprising a single carbon nanotube (CNT) covalently immobilizing a single receptor optionally being a mammalian or an insect receptor, wherein association of the VOC to said receptor allows for a measurable electric field effect.