The present invention relates to a method for detecting and/or quantifying an analyte in a sample using mass spectrometry. The method of the invention comprises: extracting the analyte from the sample using solid phase extraction (SPE) so as to obtain an SPE extract comprising the analyte, concentrating the analyte, said concentrating comprising evaporating solvent from the SPE-extract; and detecting and/or quantifying the analyte in the sample using mass spectrometry.

A system and method for purifying coenzyme Q.sub.10 are provided. The method includes: passing a CoQ.sub.10-containing crude product through a first chromatographic column to obtain a first CoQ.sub.10-containing intermediate product. The method further includes preparing, based on the first CoQ.sub.10-containing intermediate product, a second CoQ.sub.10-containing intermediate product. The method further includes passing the second CoQ.sub.10-containing intermediate product through a second chromatographic column to obtain a third CoQ.sub.10-containing intermediate product. The method further includes obtaining purified CoQ.sub.10 product by purifying the third CoQ.sub.10-containing intermediate product.

The invention relates to a method for the chromatographic purification of at least one cannabinoid compound, wherein the method comprises a main purification stage comprising the steps of: injecting an initial mixture comprising the at least one cannabinoid compound and one or more additional compounds onto a main stationary phase comprising silica particles, the silica particles comprising amino and/or diol groups; performing an elution with an elution solution, and collecting one or more elution fractions; and optionally, washing the main stationary phase with a washing solution and collecting one or more washing fractions; at least one of the elution fractions or washing fractions containing the at least one cannabinoid compound purified from the one or more additional compounds.

Provided are a method, an apparatus, and a kit for detecting a neuroblastoma in a subject and/or for monitoring a therapeutic effect on the neuroblastoma, by measuring a urinary tumor marker(s) in a sample from the subject.

A system includes a phase behavior analysis unit having a housing, a heating system connected to the housing and arranged to heat an interior of the housing, a pressure cell positioned in the interior of the housing, and a three-way valve with one inlet fluidly connected to a chamber in the pressure cell and two outlets. The system also includes a gas chromatograph that is fluidly coupled to the chamber in the pressure cell via the three-way valve.

A method for determining corrosion inhibitor residual concentration of a hydrocarbon sample is described. The hydrocarbon sample is mixed with a standard solution to form a first mixture. The standard solution includes a corrosion inhibitor in a known concentration. The first mixture is mixed with an aqueous saline solution to form a second mixture. The aqueous saline solution includes about 1% salt concentration or greater. The second mixture is agitated for about 1 hour or longer and at a temperature of about 50 degrees Celsius (° C.) or greater. After agitation, a hydrocarbon phase and an aqueous phase of the second mixture are allowed to separate. A portion of the aqueous phase is obtained. The portion of the aqueous phase is analyzed to determine a corrosion inhibitor residual concentration of the hydrocarbon sample.

Atmospheric Triphasic Chromatography (ATC) method comprising the steps introducing a raw plant material containing cannabinoids into a non-polar solvent, dissolving the cannabinoids extracted from the raw plant material in the non-polar solvent and removing the raw plant material to obtain a target solution, performing potency analysis and cannabinoid extract profile analysis of the target solution. The method further includes the steps of preparing an aqueous caustic solution and mixing the target solution with the aqueous caustic solution to obtain a mixture followed by separating the mixture into a first phase solution and a second phase solution, and removing the first phase solution to obtain a caustic target solution and acidifying the caustic target solution to produce precipitation of an undesirable compound in the caustic target solution.

A device for preparing a liquid sample for a direct injection of a corresponding gaseous sample to a micro-gas chromatograph includes: a fluid space and a gas space, which spaces are separated by a semipermeable separating layer, the fluid space including a supply line for the liquid sample, and the gas space having an outlet connectable with the gas chromatograph. The fluid space and/or the gas space is associated with at least one heating element. The device absorbs a sample volume of approximately 10 μl to 30 μl. The separating layer has a thickness of 10 μl to 300 μl and pores having a size between 0.05 μl and 5 μl.

The present invention relates to an analysis system that is applied to rapid automatic analysis and detection of highly lipophilic components and a method for rapidly detecting vitamin D in an oil or fat, or a biological sample. In the present invention, online pretreatment and separation of a sample containing highly lipophilic components in a sample to be analyzed are performed by a multidimensional chromatography system. The multidimensional chromatography system includes a supercritical chromatography part and a reverse phase liquid chromatography part sequentially connected, the reverse phase liquid chromatography part including one or more reverse phase liquid chromatography columns, and the supercritical chromatography part including a supercritical mobile phase, a modifier, and a supercritical packed column.

A preparative liquid chromatograph that separates components in a sample in a separating column and captures a plurality of target components in an eluate from the separating column in individual trap columns, includes: a column switching means configured to switch passages to cause the eluate having been eluted from the separating column and passed through a detector to selectively flow into one of the trap columns, a passage switching means disposed in a passage between the detector and the column switching means and configured to switch between a first state in which the eluate flows to the column switching means and a second state in which the eluate is discharged without flowing to the column switching means. For the switching among the trap columns, the passage switching means and the column switching means are controlled to set the passage switching means in the second state (step S17) before performing the switching operation of the column switching means (step S18). This prevents entry of a target component into a wrong trap column during the switching among the trap columns.