A system for solventless calibration of volatile or semi-volatile compounds and methods thereof. The system includes a fluid path having a first end configured to be operably coupled to a fluid source and a second end configured to be operably coupled to the analytical instrument. A solid sorbent is disposed along the fluid path and is configured to absorb an analyte. The flow of fluid along the fluid path from the first end to the second end causes absorbed analyte to be desorbed from the solid sorbent at a desired concentration to the instrument.

A system and method for utilizing a carbide-derived carbon (CDC) fiber in solid-phase micro extraction. Optically pumping the carbide-derived carbon (CDC) fiber, as compared to using thermal desorption, enhances performance of the system. CDC provides for a broad based sorbent that is insensitive to high humidity. Optical pumping may be done axially or radially on a modified gas chromatography needle. In some cases, staged, or pulsed, optical pumping is used to drive off solvent or other lower boiling compounds first and then the desorption of the remaining analytes is cleaner and the instrumentation is less likely to be overloaded.

A system and method for utilizing a carbide-derived carbon (CDC) fiber in solid-phase micro extraction. Optically pumping the carbide-derived carbon (CDC) fiber, as compared to using thermal desorption, enhances performance of the system. CDC provides for a broad based sorbent that is insensitive to high humidity. Optical pumping may be done axially or radially on a modified gas chromatography needle. In some cases, staged, or pulsed, optical pumping is used to drive off solvent or other lower boiling compounds first and then the desorption of the remaining analytes is cleaner and the instrumentation is less likely to be overloaded.

An online sample manager of a liquid chromatography system includes a fluidic tee having a first inlet port, a second inlet port, and an outlet port. A diluent pump moves diluent from a diluent source to the first inlet port of the fluidic tee. A valve has a fluidic intake port connected to a process source for acquiring a process sample therefrom. A pumping system moves the acquired process sample from the valve into the second inlet port of the fluidic tee where the process sample merges with the diluent arriving at the first inlet port to produce a diluted process sample that flows out from the outlet port of the fluidic tee.

An online sample manager of a liquid chromatography system includes a fluidic tee having a first inlet port, a second inlet port, and an outlet port. A diluent pump moves diluent from a diluent source to the first inlet port of the fluidic tee. A valve has a fluidic intake port connected to a process source for acquiring a process sample therefrom. A pumping system moves the acquired process sample from the valve into the second inlet port of the fluidic tee where the process sample merges with the diluent arriving at the first inlet port to produce a diluted process sample that flows out from the outlet port of the fluidic tee.

An opening sealing structure is provided with a housing, a step portion, a seal cap, an elastic sealing member, and a cap fixture. The housing has a cap mounting portion having a a cylindrical shape. The step portion is provided on the outer peripheral surface of the cap mounting portion and has a side surface facing the base end side of the cap mounting portion. The side surface of the step portion is inclined along the circumferential direction of the cap mounting portion from the tip end side of the cap mounting portion to the base end side and its inclination angle is smaller on the base end side of the cap mounting portion than on the tip end side. The cap fixture has a cap holding portion movably engaged with the seal cap in a circumferential direction of its outer peripheral surface and an elastic portion connected to the cap holding portion. The elastic portion is provided with a protrusion which engages the side surface of the step portion.

An opening sealing structure is provided with a housing, a step portion, a seal cap, an elastic sealing member, and a cap fixture. The housing has a cap mounting portion having a a cylindrical shape. The step portion is provided on the outer peripheral surface of the cap mounting portion and has a side surface facing the base end side of the cap mounting portion. The side surface of the step portion is inclined along the circumferential direction of the cap mounting portion from the tip end side of the cap mounting portion to the base end side and its inclination angle is smaller on the base end side of the cap mounting portion than on the tip end side. The cap fixture has a cap holding portion movably engaged with the seal cap in a circumferential direction of its outer peripheral surface and an elastic portion connected to the cap holding portion. The elastic portion is provided with a protrusion which engages the side surface of the step portion.

A sample injection device (100) includes a tubular suction and discharge unit (23) configured to suction a liquid sample (S), contain the sample therein, and discharge the suctioned sample, and at least a portion of an inner wall (23a) of the suction and discharge unit, the portion having the sample contained therewithin, is subjected to a surface treatment (V) to increase an interfacial tension (F) that acts between the inner wall and the sample.

A sample injection device (100) includes a tubular suction and discharge unit (23) configured to suction a liquid sample (S), contain the sample therein, and discharge the suctioned sample, and at least a portion of an inner wall (23a) of the suction and discharge unit, the portion having the sample contained therewithin, is subjected to a surface treatment (V) to increase an interfacial tension (F) that acts between the inner wall and the sample.

Embodiments of the disclosure relate to chemical analysis systems, including autosampler systems. In some embodiments, an autosampler system can analyze gas phase samples using a single inlet for better consistency. The autosampler system can move the sample container closer to the sample introduction/preconcentration system prior to accessing the contents of the container to reduce exposure of the sample to reactive surfaces. The autosampler system is able to couple the sample containers to a sampling wand automatically, thereby eliminating the need to pre-attach each container using a gas transfer line. The autosampler system can be disposed on top of a chemical analysis system (e.g., a GC or GCMS), thereby conserving laboratory bench space. In some embodiments, the modules (e.g., sample trays, thermal conditioning systems, support legs) of the autosampler system can be coupled to the autosampler system using clamps that include magnetic codes associated with autocalibration information.