A supercritical fluid device includes an analytical channel, a liquid delivery part for delivering a mobile phase constituting a supercritical fluid in the analytical channel, a back pressure regulator for controlling a pressure of the analytical channel so as to cause the mobile phase in the analytical channel to reach a supercritical state, a sample injecting device that includes a sample holder for holding a sample and a switching valve for switching between a state where the sample holder is arranged on the analytical channel and a state where the sample holder is not arranged on the analytical channel, a bypass channel whose one end is connected to a position upstream of the sample injecting device and whose other end is connected to a position downstream of the sample injecting device on the analytical channel, and an analytical column for separating a sample introduced by the sample injecting device into individual components, the analytical column is provided downstream of the position to which the other end of the bypass channel is connected on the analytical channel.

A process of controlling a sample separation apparatus for separating a fluidic sample includes determining whether the sample separation apparatus is appropriate for carrying out a predefined operation, by simulating the operation of the sample separation apparatus, and taking an action depending on a result of the determining.

A process of controlling a sample separation apparatus for separating a fluidic sample includes determining whether the sample separation apparatus is appropriate for carrying out a predefined operation, by simulating the operation of the sample separation apparatus, and taking an action depending on a result of the determining.

A supercritical fluid chromatograph includes a supercritical flow path, a mobile phase supply section for supplying a mobile phase containing liquid carbon dioxide, a sample introduction section, a sample separation section, a detector, and a pressure control valve. A valve post-stage flow path is connected to a fluid outlet of the pressure control valve, and the inside of the valve post-stage flow path is maintained by pressure maintaining means at a pressure by which a mobile phase from the fluid outlet of the pressure control valve is not vaporized.

A supercritical fluid chromatograph includes a supercritical flow path, a mobile phase supply section for supplying a mobile phase containing liquid carbon dioxide, a sample introduction section, a sample separation section, a detector, and a pressure control valve. A valve post-stage flow path is connected to a fluid outlet of the pressure control valve, and the inside of the valve post-stage flow path is maintained by pressure maintaining means at a pressure by which a mobile phase from the fluid outlet of the pressure control valve is not vaporized.

The present invention relates to a valve assembly, comprising a valve chamber, accesses to the valve chamber, the accesses including a first access and a second access, and a movable sealing body assembly comprising at least one sealing portion, wherein at least a portion of the sealing body assembly is magnetic, and wherein at least a portion of the sealing body assembly comprising the at least one sealing portion is located within the valve chamber. Further, the valve assembly comprises at least one sealing surface, wherein each of the at least one sealing surface is configured to complement one of the at least one sealing portion, and wherein each sealing surface comprises an orifice fluidly connected to one of the accesses. The valve assembly further comprises a force unit configured to exert a magnetic force on the magnetic portion of the movable sealing body assembly and is configured to assume at least two configurations, wherein in a first configuration, the first access is sealed, and wherein in a second configuration, the first access is fluidly connected to the second access. Further, the present invention relates to a pump system, as well as a use and manufacturing method of a valve assembly according got the present invention.

The present invention relates to a valve assembly, comprising a valve chamber, accesses to the valve chamber, the accesses including a first access and a second access, and a movable sealing body assembly comprising at least one sealing portion, wherein at least a portion of the sealing body assembly is magnetic, and wherein at least a portion of the sealing body assembly comprising the at least one sealing portion is located within the valve chamber. Further, the valve assembly comprises at least one sealing surface, wherein each of the at least one sealing surface is configured to complement one of the at least one sealing portion, and wherein each sealing surface comprises an orifice fluidly connected to one of the accesses. The valve assembly further comprises a force unit configured to exert a magnetic force on the magnetic portion of the movable sealing body assembly and is configured to assume at least two configurations, wherein in a first configuration, the first access is sealed, and wherein in a second configuration, the first access is fluidly connected to the second access. Further, the present invention relates to a pump system, as well as a use and manufacturing method of a valve assembly according got the present invention.

A fluid supply device for providing a mobile phase for a sample separating device includes, a supply conduit for providing a fluid which forms at least a part of the mobile phase, a fluid valve which is fluidically coupled with the supply conduit and, depending on its switching state, enables or prevents a passing of the fluid from the supply conduit, an elastic buffer unit which is fluidically coupled upstream of the fluid valve with the supply conduit and which is configured for buffering the fluid, and a fluid conveying unit for conveying the fluid which passes the fluid valve.

A fluid supply device for providing a mobile phase for a sample separating device includes, a supply conduit for providing a fluid which forms at least a part of the mobile phase, a fluid valve which is fluidically coupled with the supply conduit and, depending on its switching state, enables or prevents a passing of the fluid from the supply conduit, an elastic buffer unit which is fluidically coupled upstream of the fluid valve with the supply conduit and which is configured for buffering the fluid, and a fluid conveying unit for conveying the fluid which passes the fluid valve.

Systems for use with liquid chromatography for provision of continuous flow or gradient flow in connection with two pumps providing mobile phase to a valve.