Disclosed is a device for chromatographic separations comprising: a manifold comprising a manifold body defining an elongate central duct, the central duct comprising a centrally-located closable duct valve providing selective fluid communication between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the branch ducts of the first plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the first portion of the central duct, a second plurality of branch ducts, each branch duct of which extending from the second portion of the central duct to an individual one of the second plurality of connectors, each of the branch ducts of the second plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the second portion of the central duct; first and second ports in fluid communication with the centrally-located closable duct valve wherein said first port communicates with said first portion of the central duct and said second port communicates with said second portion of said central duct, wherein one of said first and second ports is further positioned to communicate with said central duct at a location between the centrally-located closable duct valve and the first and second plurality of branch ducts, respectively.

Disclosed is a device for chromatographic separations comprising: a manifold comprising a manifold body defining an elongate central duct, the central duct comprising a centrally-located closable duct valve providing selective fluid communication between a first portion of the central duct and an opposed second portion of the central duct, a first plurality of connectors, each connector of the first plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; a second plurality of connectors, each connector of the second plurality of connectors for connecting to a distinct chromatographic separation column and/or feed or extraction tubing or to a connector of an adjacent manifold; wherein said manifold body further defines: a first plurality of branch ducts, each branch duct of which extending from the first portion of the central duct to an individual one of the first plurality of connectors, each of the branch ducts of the first plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the first portion of the central duct, a second plurality of branch ducts, each branch duct of which extending from the second portion of the central duct to an individual one of the second plurality of connectors, each of the branch ducts of the second plurality of branch ducts comprising a closable branch valve providing selectable fluid communication between a respective connector and the second portion of the central duct; first and second ports in fluid communication with the centrally-located closable duct valve wherein said first port communicates with said first portion of the central duct and said second port communicates with said second portion of said central duct, wherein one of said first and second ports is further positioned to communicate with said central duct at a location between the centrally-located closable duct valve and the first and second plurality of branch ducts, respectively.

An extraction cell (10) for a centrifugal partition chromatograph (20), which extraction cell (10) contains an extraction chamber (12) delimited by a cell wall (12c) and accommodates the liquid stationary phase (30á), and it has a liquid inlet opening (13b) and a liquid outlet opening (13k) serving to let in and out the liquid mobile phase (30m) to be made to flow through the extraction cell (10). The extraction cell (10) contains an extraction chamber (12) established as a tubular body, and a liquid inlet plug (16b) that includes a liquid inlet opening (13b) and a liquid outlet plug (16k) that includes a liquid outlet opening (13k), that can be attached to the extraction chamber (12) and an insert (14) through which liquids may pass is positioned in the extraction chamber (12) between the liquid inlet opening (13b) and the liquid outlet opening (13k). A further objective relates to a centrifugal partition chromatograph (20) containing such an extraction cell (10), and a method for providing such an extraction cell (10).

An extraction cell (10) for a centrifugal partition chromatograph (20), which extraction cell (10) contains an extraction chamber (12) delimited by a cell wall (12c) and accommodates the liquid stationary phase (30á), and it has a liquid inlet opening (13b) and a liquid outlet opening (13k) serving to let in and out the liquid mobile phase (30m) to be made to flow through the extraction cell (10). The extraction cell (10) contains an extraction chamber (12) established as a tubular body, and a liquid inlet plug (16b) that includes a liquid inlet opening (13b) and a liquid outlet plug (16k) that includes a liquid outlet opening (13k), that can be attached to the extraction chamber (12) and an insert (14) through which liquids may pass is positioned in the extraction chamber (12) between the liquid inlet opening (13b) and the liquid outlet opening (13k). A further objective relates to a centrifugal partition chromatograph (20) containing such an extraction cell (10), and a method for providing such an extraction cell (10).

A method for removing sulfur-containing compounds from methanol, said method comprising the step of subjecting methanol comprising sulfur-containing compounds to centrifugal countercurrent chromatography (CCCC) to remove sulfur-containing compounds, and the use of centrifugal countercurrent chromatography (CCCC) for removing sulfur-containing compounds from methanol.

A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to produce a first mixed output, a stage I separator for concentrating the first mixed output to produce a stage I solid fraction, a second mixer for mixing the stage I solid fraction from the stage I separator and an optional buffer solution to produce a second mixed output, and a stage II separator for concentrating the second mixed output to produce a stage II solid fraction which exits the module. At least one separator is a spiral separator. The system includes a plurality of modules, and at least one of the plurality of modules includes a spiral separator. The method includes purifying an unpurified solution with the plurality of modules.

A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to produce a first mixed output, a stage I separator for concentrating the first mixed output to produce a stage I solid fraction, a second mixer for mixing the stage I solid fraction from the stage I separator and an optional buffer solution to produce a second mixed output, and a stage II separator for concentrating the second mixed output to produce a stage II solid fraction which exits the module. At least one separator is a spiral separator. The system includes a plurality of modules, and at least one of the plurality of modules includes a spiral separator. The method includes purifying an unpurified solution with the plurality of modules.

A method for removing sulfur-containing compounds from crude sulfate turpentine (CST), said method comprising the step of: subjecting CST to continuous liquid-liquid extraction to remove sulfur-containing compounds.

A method for removing sulfur-containing compounds from crude sulfate turpentine (CST), said method comprising the step of: subjecting CST to continuous liquid-liquid extraction to remove sulfur-containing compounds.

A flying leads assembly includes a flying lead having an inner layer which forms a liquid passage and an outer layer which acts as a sacrificial layer in use, thereby allowing integrity of the passage to be maintained for a long period of time. A further layer is provided intermediate the inner and outer layers which can be used to provide support to the assembly. The flying lead assembly, or a number of assemblies, are then located in a guide with lubricant material.