The present invention relates to a nanovesicle comprising a heterodimeric G-protein coupled receptor, a method for preparing the nanovesicle, a field effect transistor-based taste sensor comprising the nanovesicle, and a method for manufacturing the taste sensor. The field effect transistor based taste sensor functionalized by the nanovesicle comprising the heterodimer G-protein coupled receptor according to the present invention has excellent sensitivity and selectivity and may highly specifically detect a sweet taste substance in real time, by using the heterodimeric G-protein coupled receptor and the nanovesicle comprising the same.

A device for handling a particle suspension, in particular a cell suspension, which includes at least one channel for flowing the particle suspension, a pumping unit configured to move a driving fluid and control element for controlling the pumping unit. Also, a method for handling a particle suspension, which includes flowing the particle suspension in or out of at least one channel using a driving fluid for driving the particle suspension in the channel.

Disclosed are methods and kits for analyzing a sample comprising 1,5-anhydroglucitol and a possible first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte. Also provided are kits including reagents for practicing the claimed methods.

Disclosed herein is a molecular imprinted protective face mask comprising a supportive structure, a surface material that receives and retains a molecular imprint and that is positioned to contact airborne molecules during use, a molecular imprint of a bioactive molecule wherein an imprinted cavity is at least one of a bioactive molecule with a molecular configuration that captures a specific airborne and/or microdroplet-borne molecule and a protein with a binding site that captures a specific molecule.

The present invention relates to a biochemical assay apparatus in which a sample processing device is controlled by a detection instrument through a series of linear and rotary actuations to execute a biochemical assay on a biological fluid sample.

A photoionization detector comprised of a gas discharge lamp that ionizes molecules of interest to create ionized molecules and electrons and a sensor having at least one opening for UV light to pass through and electrically conductive patterns on the top and bottom surfaces of the plate. A negative electrical potential pattern can be on one of the top or the bottom surface and can include an interior portion that is at least a first distance away from every edge of the at least one opening. An electron collecting electrode pattern can be on the other of the top or the bottom surface and can substantially fill an area surrounding the opening such that the negative electrical potential pattern and the electron collecting electrode pattern are offset relative to each other. The ionized molecules are collectable by a bias electrode and electrons are collectable by a collector electrode.

A photoionization detector comprised of a gas discharge lamp that ionizes molecules of interest to create ionized molecules and electrons and a sensor having at least one opening for UV light to pass through and electrically conductive patterns on the top and bottom surfaces of the plate. A negative electrical potential pattern can be on one of the top or the bottom surface and can include an interior portion that is at least a first distance away from every edge of the at least one opening. An electron collecting electrode pattern can be on the other of the top or the bottom surface and can substantially fill an area surrounding the opening such that the negative electrical potential pattern and the electron collecting electrode pattern are offset relative to each other. The ionized molecules are collectable by a bias electrode and electrons are collectable by a collector electrode.

The present invention provides methods and devices for simple, low power, automated processing of biological samples through multiple sample preparation and assay steps. The methods and devices described facilitate the point-of-care implementation of complex diagnostic assays in equipment-free, non-laboratory settings.

This automated analyzer comprises a first system 11 that does not need to use degassed water, a second system 12 for which it is preferable to use degassed water and that comprises a degassing device 21 for producing degassed water and a second pump 19 for delivering the degassed water, and a tank 1 having formed therein a first compartment 4 for storing water to supply to the first system 11 and a second compartment 5 for storing degassed water to supply to the second system 12. The second system 12 comprises a circulation system, which comprises a suction flow path 20 and return flow path 24 for connecting the degassing device 21, the second pump 19, and the second compartment 5 of the tank 1, and a usage system, which comprises a discharge flow path 22 and connection flow path 27 for connecting the degassing device 21 and a usage unit for using the degassed water. Provided inside the tank 1 are a partition 3 for forming the first compartment 4 and second compartment 5 and a water passage part 6 where water moves between the first compartment 4 and second compartment 5.

A configurable device arrangement for performing at least one unit operation in a biopharmaceutical process includes a base rack and a plurality of holders for releasable direct or indirect attachment of process components, in particular single-use process components, for the unit operation. The holders are in turn adapted to be releasably attached directly or indirectly to the base rack. The device arrangement further includes a positioning system which defines specific positions for the holders relative to the base rack.