Examples herein involve amplification and detection of nucleic acids using a microfluidic reaction chamber. An example apparatus includes a reaction-chamber circuit to process a reagent and a biologic sample for amplification of nucleic acids. The apparatus further includes a plurality of capillaries to pass the reagent and the biologic sample through the microfluidic reaction chamber. A valve control system may selectively control each of a plurality of valves to cause the reagent and the biologic sample to selectively move through the microfluidic reaction chamber for the amplification of the nucleic acids according to a particular timing sequence. In various examples, a trapping region disposed in the microfluidic reaction chamber secures the nucleic acids in the microfluidic reaction chamber for amplification using the reaction-chamber circuit.

A well plate cover includes a base defining a base plane, and a plurality of insertion elements. At least a portion of each of the insertion elements is transparent. Each of the insertion elements is coupled to the base, and extends, in a direction orthogonal to the base plane, from the base to a distal end surface of the insertion element. The distal end surface of each of the insertion elements includes an apex that, when the respective insertion element is inserted into a well of a well plate, extends further into the well than any other portion of the distal end surface. The apex is a point, a line, or a plane having a diameter that is less than one half of a maximum diameter of the distal end surface.

Disclosed herein is a molecular imprinted protective face mask comprising a supportive structure, a surface material that receives and retains a molecular imprint and that is positioned to contact airborne molecules during use, a molecular imprint of a bioactive molecule wherein an imprinted cavity is at least one of a bioactive molecule with a molecular configuration that captures a specific airborne and/or microdroplet-borne molecule and a protein with a binding site that captures a specific molecule.

An embodiment of the present disclosure provides a microfluidic chip, including: a first substrate; wherein the first substrate includes a first base, a first electrode layer on the first base; the first electrode layer includes a plurality of first electrodes at intervals along a first direction, wherein a cross-sectional shape of the first electrode parallel to the first base is a centrosymmetric shape, and the cross-sectional shape includes: a first boundary and a second boundary opposite to each other in the first direction; a shape of the first boundary is a centrosymmetric curve, a distance between two end points of the first boundary in a second direction perpendicular to the first direction is less than a length of the first boundary; the second boundary has a same shape and length as the first boundary, and the first and second boundaries are parallel to each other in the first direction.

In an automatic analysis device, it is possible during specimen analysis to add/deposit one rack at a time without stopping the analysis, and it is easy to ascertain the analysis sequence. The analyzer has an analysis module, a rack transport module for transporting a specimen rack in which a specimen container storing a specimen is loaded, and a control device. The rack transport module includes a rack supply part for supplying a specimen rack, a rack accommodating part for accommodating a specimen rack, a rack transport line for transporting a specimen rack supplied from the rack supply part, a dispensing line for transporting a specimen rack to the analysis module, and a rack rotor for transferring a specimen rack between the rack transport line and the dispensing line. Operation of the rack supply part for supplying a specimen rack can be stopped independently of the operation of the analysis module.

A microfluidic apparatus for delivering droplets of a first fluid to droplets of a second fluid, comprising a main channel, with a carrier fluid carrying droplets of the second fluid, an auxiliary channel, fluidly coupled to the main channel at a first intersection via a first orifice with a first fluid interface, and at a second intersection downstream to the first intersection via a second orifice with a second fluid interface, wherein a flow of the carrier fluid induces a difference of pressure between the first and second orifice generating a balance condition such that a meniscus of the second fluid interface is maintained in the auxiliary channel, at the vicinity of the second orifice, wherein a balance deviation triggers a release of a volume of the first fluid from the second fluid interface into the main channel.

A method for evaluating a mass spectrometry device includes: by a mass spectrometry device, performing mass spectrometry of an ester of phthalic acid and detecting a plurality of types of ions produced by dissociation of the ester of phthalic acid; and obtaining information concerning whether the mass spectrometry device is in a state suitable for analysis, based on a ratio of intensities of the plurality of types of ions detected.

A nutrient intake amount estimation system according to an embodiment includes: a sensor that is disposed in a toilet space, and configured to detect an excretion smell related to excretion of a user of the toilet space; an estimation unit configured to estimate an estimated nutrient intake amount that is an amount of nutrients taken by the user by using an output of an estimation model that outputs information indicating an amount of nutrients estimated to be taken by the user in accordance with an input based on an output value of the sensor; and an output unit configured to output information based on the estimated nutrient intake amount.

Devices, systems, and their methods of use, for generating and collecting droplets are provided. The device includes a collection region comprising a side wall canted at an angle. The invention further provides multiplex devices that increase droplet formation.

Improved methods and devices using reduction of pressure for removing ethanol from filters in a fluidic or microfluidic system in point of care devices involve filters that are solid state extraction filters used to capture and/or concentrate nucleic acids prior to further downstream processing such as amplification by polymerase chain reaction. The method uses the induction of negative pressure with respect to atmospheric pressure to improve the efficiency of the ethanol removal process.