The present disclosure proposes, in order to increase a liquid temperature in a reaction tank to a predetermined temperature in a short time without increasing a capacity of a heater, an automatic analyzer including: the reaction tank configured to hold a liquid in which a reaction vessel configured to contain a reaction liquid is to be immersed; a pump configured to circulate the liquid and supply the liquid to the reaction tank; the heater configured to heat the liquid; a Peltier element configured to heat and cool the liquid; a first temperature sensor configured to detect a temperature of the liquid; and a control device configured to control an output of the heater and an output of the Peltier element based on the temperature detected by the first temperature sensor.

A temperature control device and method are provided for an analytical system for performing laboratory protocols. The device includes a well within a housing configured to receive a biological specimen according to a predetermined sample process. The specimen is suspended by a holding device in the well. A thermal element is provided in heat exchange communication with fluid in the well. A temperature sensor is located in the well at a location to be covered and uncovered by rocking motion of fluid in the well. A controller, in communication with the thermal element, the temperature sensor, and an agitation system, is operative to control the thermal element in correlation with temperature data, for example, peak temperature data, from the temperature sensor.

A system includes a first base, a second base, a cable, and a control portion. The first base has a first heating element configured to heat a first functional component to increase the temperature of a fluid within the first functional component. The second base has a second heating element configured to heat a second functional component to dry one or more specimen slides. The cable couples the first base to the second base. The control portion is in communication with both the first heating element and the second heating element to control the first heating element and the second heating element simultaneously.

A system includes a base, a first accessory component, and a second accessory component. The base includes a receiving body and a control portion. The receiving body includes a receiver and a heating element proximate the receiver. The control portion includes one or more user interface features configured to control the heating element. The first accessory component is configured to process one or more tissue samples after sectioning using a microtome and is further configured for receipt with the receiver. The second accessory component is configured for receipt within the receiver. The first accessory component is configured for a different processing function of one or more tissue samples after sectioning using the microtome relative to the second accessory component. The first accessory component and the second accessory component are configured to be interchangeably received within the receiver.

An amplicon separation apparatus and process for enabling the identification of a plurality of target DNA molecules in a sample such as blood, the apparatus including a consumable and a docking instrument for receiving the consumable. The consumable incorporates a reaction vessel heating station, a reaction vessel content transfer station, an amplicon size separation station, and a reader station. The instrument controls and monitors the consumable and the operation thereof.

A heat removal module slice constructed to service a row of reaction vessels, the slice being in the form of a block of thermally conductive material having a row of reaction stations at an edge thereof, at one end thereof a liquid entry manifold and at the other end thereof a liquid exhaust manifold; and a heat exchanger liquid channel adjacent the reaction stations and extending between the two manifolds. The slice is constructed to form, with a plurality of similar slices, a heat reduction module for incorporation in a reaction, typically a PCR reaction, apparatus and process.

Disclosed herein are high-throughput sample processing systems and waste management systems, and methods of using the same.

An automatic analysis apparatus is capable of replacing circulated water in a reaction vessel and continuously cooling a light source lamp without stopping an operation for measuring a specimen. In an operation state, a drain electromagnetic valve 49 is opened to drain reaction vessel water outside and when the water level reaches a measurement limit water level, the drain electromagnetic valve 49 is closed. The reaction vessel water is supplied by starting a water supply pump, opening a water supply electromagnetic valve and when the water level has reached a full water level, the water supply electromagnetic valve is closed, and the water supply pump is stopped. In a state other than the operation state, the reaction vessel water is drained outside. When the water level has reached a circulation limit water level, the drain electromagnetic valve is closed.

Disclosed herein are high-throughput sample processing systems and waste management systems, and methods of using the same.

A process for the identification of genetic material in a biological liquid sample and including the steps of injecting into a reaction vessel containing freeze dried PCR reagents and labelled primers sufficient pure water to liquify the reagents and primers; injecting the biological liquid sample into the reaction vessel; subjecting the reaction vessel contents to a cell disruption process, in the said reaction vessel; conducting pathogen specific polymerase chain reaction (PCR) on the contents of the reaction vessel; and monitoring the PCR and determining therefrom the presence of a specific genetic material. A device for performing the process comprises a heat reduction module (HRM); a peltier cell (TEC) the base plate whereof is contiguous with the HRM; a reaction vessel receiving heat transfer sleeve contiguous with a working face of the TEC; retention means for holding a reaction vessel in the sleeve; and means for driving the TEC.