This automated analyzer comprises a first system 11 that does not need to use degassed water, a second system 12 for which it is preferable to use degassed water and that comprises a degassing device 21 for producing degassed water and a second pump 19 for delivering the degassed water, and a tank 1 having formed therein a first compartment 4 for storing water to supply to the first system 11 and a second compartment 5 for storing degassed water to supply to the second system 12. The second system 12 comprises a circulation system, which comprises a suction flow path 20 and return flow path 24 for connecting the degassing device 21, the second pump 19, and the second compartment 5 of the tank 1, and a usage system, which comprises a discharge flow path 22 and connection flow path 27 for connecting the degassing device 21 and a usage unit for using the degassed water. Provided inside the tank 1 are a partition 3 for forming the first compartment 4 and second compartment 5 and a water passage part 6 where water moves between the first compartment 4 and second compartment 5.

To provide an automatic analyzer capable of relaxing the effect of a previously created mixed liquid when a new mixed liquid is created. An automatic analyzer according to the present disclosure: is configured so as to create a second mixed liquid after a first mixed liquid is created; and introduces a relaxation reagent to relax the effect of a first reagent remaining in a mixed liquid chamber when the second mixed liquid is created into the mixed liquid chamber on the basis of characteristics of the first mixed liquid.

Provided is an automatic analysis device capable of replenishing consumables without loss of a specimen and without stopping analysis. The state of an automatic analysis device 100 includes a replenishment prohibition state in which replenishment of consumables (reaction vessel 8, specimen dispensing tip 10a and external reagent vessels 21a, 21b, 21c) is prohibited, and a replenishment permission state in which replenishment of consumables is permitted. In the replenishment prohibition state, a specimen dispensing mechanism 10 performs dispensing, and detection units 18a and 18b perform analysis. In the replenishment permission state, the specimen dispensing mechanism 10 does not perform dispensing, and the detection units 18a and 18b perform analysis. A device state control unit 119d causes the automatic analysis device 100 to transition to the replenishment permission state when the remaining amount or the remaining number of the consumables predicted by a consumables remaining amount prediction unit 119b becomes equal to or less than a predetermined value.

A maintenance method in an automatic analysis apparatus includes: a recognition step of recognizing an integrated rack 301A, 301B, 301C mounted with a cleaning solution container containing a cleaning solution, and a calibrator container containing a calibrator or a QC specimen container containing a QC specimen containing a sample having a known concentration; a cleaning solution supply step of aspirating a cleaning solution; and a supply step of aspirating the calibrator or aspirating the QC specimen, in which the cleaning solution supply step and the supply step are continuously performed from the cleaning solution container and the calibrator container or the QC specimen container mounted on the integrated rack 301A, 301B, 301C. Accordingly, an automatic analysis apparatus and a maintenance method in the automatic analysis apparatus that can reduce a burden on a user in calibration and the like during maintenance are provided.

To provide an automated analyzer adapted for accommodating a larger number of reagent cassettes to meet calls for increases in analytical throughput and in the number of analytical items, and thus using the accommodated reagent cassettes more efficiently. An automated analyzer body 100 includes a main reagent buffer 4 for storing a plurality of reagent cassettes each containing a reagent used for analysis and a subsidiary reagent buffer 12. A reagent cassette transfer 11 transfers the reagent cassettes from the main reagent buffer to the subsidiary reagent buffer, and vice versa. A control unit 200 operates so that when a reagent cassette that is not set in the main reagent buffer is to be used for an assigned analysis, the reagent cassette for the assigned analysis is transferred from the subsidiary reagent buffer to the main reagent buffer.

A method for supplying consumable items to an automated sample analyzer is presented. The automated analyzer comprises a consumable repository including two or more storage areas. Each area is configured to store a plurality of consumable items. The method comprises receiving one or more orders for analytical tests to be carried out by the analyzer, reserving consumable items corresponding to one or more sets of consumable items required for the analytical tests in a first area, switching to a second area for reserving consumable items in response to determining that a predetermined consumable item in the first area has been reserved, supplying the reserved consumable items for use in the one or more analytical tests and indicating that the first area can be replenished in response to determining that a particular consumable item of the first storage area has been used.

An automatic analyzer which realizes stable reagent heating and high dispensing accuracy includes a thermostat bath for controlling a reagent or a reaction solution in reaction cells arranged on a circumference of a reaction disk to have a constant temperature; a first reagent dispensing mechanism dispenses a reagent into the reaction cells; a photometer detects transmitted light or scattered light in the reaction cell; and a disposable reaction container for allowing the sample and the reagent to mix and react with each other. The analyzer also includes a second reagent dispensing mechanism with a reagent heating function which dispenses the reagent into the disposable reaction container; a coagulation time detection section; a reaction container temperature control block; a reagent dispensing syringe which is connected to the second reagent dispensing mechanism; and a fluid temperature control mechanism which controls the temperature of an internal fluid of the reagent dispensing syringe.

Improved component tracking methods and systems are disclosed herein. The use of suspended reagent and/or sample identifiers are described as well as the use of suspended and supplemental identifiers to enhance component tracking in assay systems.

The invention relates to a method of preparing a biological sample for study in an analysis device, said method comprising the steps of: providing a biological material to be studied; providing a sample holder that is configured to be placed in said analysis device; and transferring said biological material onto said sample holder for preparing said biological sample. According to the invention, the method comprises the steps of: acquiring a specimen of said biological material provided on said sample holder; transferring said specimen to a screening device for screening said specimen; and evaluating said biological sample based on results obtained by said screening device. With the method, time and resources may be more effectively used in studying biological samples, for example using charged particle microscopy in the form of cryo-EM.

A multi-well fluid container that includes a container body is provided for use in an in vitro diagnostics automation system. The container body includes a first well having a first well size configured to hold a first fluid and an openable first well closure that covers a first well opening. The first well opening provides access to the first fluid in the first well when the openable first well closure is opened. The container body also includes a second well having a second well size configured to hold a second fluid and having an openable second well closure that covers a second well opening. The second well opening provides access to the second fluid in the second well when the openable second well closure is opened. The first well size of the first well is different than the second well size of the second well.