An apparatus includes a sample carrier having wells. Each of the wells has sides and a floor forming an interior. A surface enhanced Raman spectroscopy (SERS) structure is within the interior of each of the wells. A pneumatic port is connected to the interior of each of the wells. A pneumatic passage is connected to the pneumatic ports.

Provided are nucleic acid extraction apparatuses and operation methods thereof. The apparatus may include at least one cyclically moveable annular structure, at least one pipetting mechanism, at least one injection mechanism and a driving mechanism. The annular structure may be provided with a plurality of cuvette positions and a plurality of operation positions. The pipetting mechanism and the injection operation may be arranged along the annular structure. The driving mechanism may drive the annular structure to move cyclically.

A wash system for use in an in vitro diagnostic immunoanalyzer utilizes a bridge having a linear track to move cuvettes from one incubation ring portion to another incubation ring portion. Washing stations along the linear track provide a magnetic field and fluid washing of cuvette contents independent of the size and motion of one or more incubation rings.

Disclosed is an automatic cleaning and separating device for removing uncombined components in reactants in a reaction container. The automatic cleaning and separating device includes: a liquid injection and uniform mixing mechanism, a removal assembly and a liquid suction mechanism; wherein a liquid injection driver is mounted on the liquid injection and uniform mixing mechanism, a liquid suction driver is mounted on the liquid suction mechanism, the liquid injection driver drives the liquid injection and uniform mixing mechanism to move up and down so as to complete liquid injection, the liquid suction driver drives the liquid suction mechanism to move up and down to complete liquid suction, and the removal assembly removes the reaction container from the liquid injection and uniform mixing mechanism under the relative motion of the liquid suction mechanism and the liquid injection and uniform mixing mechanism.

According to one embodiment, there is provided an automatic analyzing apparatus which comprises determination processing circuitry, an analyzer mechanism and data processing circuitry. The determination processing circuitry determines whether to continue reaction of a solution mixture based on reaction data. The analyzer mechanism generates analytical data based on test data generated by measuring the solution mixture. The data processing circuitry performs control such that the analytical data is generated in a first measurement section if it is determined that continuation of the reaction of the solution mixture is unnecessary, and the analytical data is generated by measuring the solution mixture after the first measurement section if it is determined that continuation of the reaction of the solution mixture is necessary.

One actuator (a gripper mechanism and reagent bottle lid opening mechanism drive unit 120) drives a gripper mechanism 106 that holds a reagent bottle 10 and a reagent bottle lid opening mechanism 104 that incises a lid of the reagent bottle 10. The gripper mechanism 106 operates to ascend when the reagent bottle lid opening mechanism 104 operates to descend in order to incise the reagent bottle lid 112, and the reagent bottle lid opening mechanism 104 operates to ascend when the gripper mechanism 106 operates to descend in order to hold the reagent bottle 10. The reagent bottle lid opening mechanism 104 and the gripper mechanism 106 operate without interfering with each other's functions.

Provided are a device and a cleaning mechanism for a reaction container in the device that are characterized by being provided with: a reaction disk for holding a reaction container; a sample dispensing mechanism for dispensing a sample to the reaction container; a reagent dispensing mechanism for dispensing a reagent to the reaction container; an optical system comprising a light source for applying light to a mixture of the sample and the reagent dispensed to the reaction container, and a detector for detecting the light applied from the light source; and a cleaning mechanism for cleaning the reaction container, wherein the cleaning mechanism is provided with a cleaning liquid supply nozzle for supplying a cleaning liquid to the reaction container after an analysis, a cleaning liquid suction nozzle for suctioning the supplied cleaning liquid, and a cleaning tip provided on the lower end of the cleaning liquid suction nozzle, and the side surface of the cleaning tip is formed such that the width of the cleaning tip becomes smaller downward, in the state where the cleaning tip is inserted into the reaction container, in at least a surface opposing the light source and a surface opposing the detector, and in a range that overlaps with a photometric range in which light applied to the reaction container from the light source passes through the reaction container toward the detector or in a range that is larger than the photometric range.

The disclosure concerns a method for operating an automated analyzer, including transporting a liquid containing a plurality of particles into a chamber, such as a reactor chamber and/or measuring cell chamber of the analyzer, introducing a gas or gas mixture, for example, air into the chamber, such as through the liquid present in the chamber so that the particles in the liquid are stirred up, and subsequently draining at least part of the liquid from the chamber through a fluid line ending in the chamber and an open valve arranged in the fluid line.

The present disclosure relates to a magnetic microbeads adsorption mechanism, which is configured to adsorb a magnetic microbeads in a reaction cup and is provided with a cup inlet station and a cup outlet station; the magnetic microbeads adsorption mechanism includes a pedestal, a turntable and multiple magnetic adsorption components; the turntable is rotatably mounted on the pedestal; the turntable can drive the reaction cup to rotate around a central axis of the turntable; the multiple magnetic adsorption components are arranged on a mounting circumference of the pedestal at intervals; the mounting circumference and rotation track of the reaction cup are concentrically arranged; and during a process when the reaction cup rotates from the cup inlet station to the cup outlet station, the adsorption height of the magnetic microbeads relative to cup bottom of the reaction cup can be changed.

To provide a technique that is related to a cleaning mechanism of an automatic analyzer and which is adapted to reduce variability of a cleaning range in a reaction vessel so that blank value measurement and the like are less affected by the variability of the cleaning range. The automatic analyzer controls a sequence including optical measurement and cleaning and includes a discharge mechanism including a discharge nozzle for discharging a liquid into a reaction vessel; and an overflow suction mechanism including an overflow suction nozzle for sucking an overflow amount of the liquid in the reaction vessel. In a liquid discharge step included in a cleaning process and interposed between a preceding step using a detergent and a succeeding blank value measurement step, the automatic analyzer establishes a first state where a lower end of the discharge nozzle is located at a first position in a heightwise lower part of the reaction vessel and a lower end of the overflow suction nozzle is located at a second position in an upper part of the reaction vessel, and provides control so as to carry out the discharge of liquid from the discharge nozzle and the suction of the overflow amount of liquid through the overflow suction nozzle.