Patent classifications
G01R33/4804
Precision Delivery of Energy Utilizing Holographic Energy Teleportation (HET) with Time-Correlated Standing-Wave Interference and Coherent Intensity Amplification
By producing the proper wave interference using superimposed waves that overlap with the proper time-phase relationship (called “Time-Correlated Standing-wave Interference”), wave energy is amplified (by “Coherent Intensity Amplification”) and teleported to precise locations. For instance, in one application, energy is teleported to one or more areas within a living body for such therapeutic applications as destroying cancer cells or plaques within arteries. A system implementing this technique creates amplified constructive interference at one or more selected disease locations, while producing destructive interference at surrounding locations. In this application example, the technique allows energy to be “teleported” to tumor cells, plaques, or other diseased cells, for instance, to destroy them, while surrounding healthy cells receive virtually no energy, obviating collateral damage from the treatment. The same method can be used to diagnose disease by detecting energy teleported to different locations.
Measuring the wettability of porous media based on the temperature sensitivity of nuclear magnetic resonance relaxation time
The present disclosure describes methods and systems, including computer-implemented methods, computer program products, and computer systems, for measuring wettability of a rock sample. One method includes: at each temperature of a plurality of temperatures, obtaining a first Nuclear Magnetic Resonance (NMR) surface relaxation time for a rock sample having a saturation level; determining a first temperature sensitivity based on the first NMR surface relaxation times and corresponding temperatures; at each temperature of the plurality of temperatures, obtaining a second NMR surface relaxation time for the rock sample that is saturated with oil; determining a second temperature sensitivity based on the second NMR surface relaxation times and corresponding temperature; and determining a wettability of the rock sample based on the first temperature sensitivity and the second temperature sensitivity.
MRI PHANTOM HAVING FILAMENTS OF INTEGRAL TEXTILE AXON SIMULATIONS AND ANISOTROPIC HOMOGENEITY MRI PHANTOM USING THE FILAMENTS
An MRI phantom for calibrated anisotropic imaging includes a plurality of separate sheathed taxons or integral taxons sharing common taxon walls, wherein each taxon has an inner diameter of less than 2 microns. The taxons form taxon filaments that are combined to form taxon ribbons. The taxons may have an average inner diameter of less than 1 micron, specifically about 0.8 microns with a packing density of about 1,000,000 per square millimeter. The filaments may include structural features such as an outer frame and crossing support ribs and may further include a visible alignment feature that allows for verifying orientation of an individual filament. The taxons may be formed as taxon fibers manufactured using a bi or tri-component textile/polymer manufacturing process. An anisotropic homogeneity phantom may include frame members that support fiber tracks extending in orthogonal directions, wherein each fiber track is formed of taxons.
Local shimming system for magnetic resonance imaging and method thereof
A local shimming system for magnetic resonance imaging and the method thereof, wherein the shimming method comprises the following steps: collecting B0 field map information using two-dimensional gradient echo (301); calculating and evaluating the homogeneity of B0 (302); optimizing the current of each channel shim coil (303); determining whether the minimum standard deviation value of Δf is obtained (304); outputting an optimal current combination values and setting an optimum current value corresponding to each channel of the shim coil on the current control software (305); and testing and evaluating the homogeneity of B0 to achieve the shimming goal (306).
Cartesian-radial hybrid k-space trajectory for volumetric imaging
An MRI system uses a Cartesian-radial hybrid k-space trajectory to capture three-dimensional k-space data and reconstruct an image of an area of interest of a subject. The MRI system performs a series of k-space acquisitions to collect the data. A first k-space acquisition includes acquiring a two-dimensional EPI projection in a first plane parallel to a frequency-encoding direction and acquiring additional two-dimensional EPI projections in planes that are radially shifted about a center axis parallel to the frequency-encoding direction with respect to the first plane, until a selected number of projections are acquired. Each subsequent k-space acquisition includes acquiring an additional set of two-dimensional EPI projections in all of the planes in which an EPI projection was acquired during the first k-space acquisition, each additional set of EPI projections being shifted along a respective plane in a direction perpendicular to the frequency-encoding direction.
METHOD FOR FILTERING ERRONEOUS PIXELS IN A THERMAL THERAPY CONTROL SYSTEM
During the delivery of thermal therapy, the measured temperature at each pixel in a cross-sectional temperature slice of a multi-pixel thermal image is compared to a maximum temperature limit. When the measured temperature of a pixel is higher than the maximum temperature limit for a predetermined number of consecutive cross-sectional temperature slices, the pixel is masked if the absolute value of the average difference between the measured temperature at the pixel and the measured temperatures at the pixel's neighbors is greater than a maximum temperature variation. The measured temperature of the masked pixel is ignored in subsequent cross-sectional temperature slices until the delivery of thermal therapy is complete.
Guiding Protocol Development for Magnetic Resonance Thermometry
A method for decomposing noise into white and spatially correlated components during MR thermometry imaging includes acquiring a series of MR images of an anatomical object and generating a series of temperature difference maps of the anatomical object. The method further includes receiving a selection of a region of interest (ROI) within the temperature difference map and estimating total noise variance values depicting total noise variance in the temperature difference map. Each total noise variance value is determined using a random sampling of a pre-determined number of voxels from the ROI. A white noise component and a spatially correlated noise component of the total noise variance providing a best fit to the total noise variance values for all of the random samplings are identified. The white noise component and the spatially correlated noise component are displayed on a user interface.
LOCAL SHIMMING SYSTEM FOR MAGNETIC RESONANCE IMAGING AND METHOD THEREOF
A local shimming system for magnetic resonance imaging and the method thereof, wherein the shimming method comprises the following steps: collecting B0 field map information using two-dimensional gradient echo (301); calculating and evaluating the homogeneity of B0 (302); optimizing the current of each channel shim coil (303); determining whether the minimum standard deviation value of f is obtained (304); outputting an optimal current combination values and setting an optimum current value corresponding to each channel of the shim coil on the current control software (305); and testing and evaluating the homogeneity of B0 to achieve the shimming goal (306).
Systems and methods for targeted deep hyperthermia by time-shared RF inductive applicators
The present disclosure provides, inter alia, a system and methods for targeted hyperthermia effective to differentially heat target organs. In certain embodiments, the system and/or method utilizes one or more pairs of inductive applicators coupled to the one or more RF generators and configured to deposit radio frequency radiation on a region of interest based on a set of configurable parameters.
Measuring the wettability of porous media based on the temperature sensitivity of nuclear magnetic resonance relaxation time
The present disclosure describes methods and systems, including computer-implemented methods, computer program products, and computer systems, for measuring wettability of a rock sample. One method includes: at each temperature of a plurality of temperatures, obtaining a first Nuclear Magnetic Resonance (NMR) surface relaxation time for a rock sample having a saturation level; determining a first temperature sensitivity based on the first NMR surface relaxation times and corresponding temperatures; at each temperature of the plurality of temperatures, obtaining a second NMR surface relaxation time for the rock sample that is saturated with oil; determining a second temperature sensitivity based on the second NMR surface relaxation times and corresponding temperature; and determining a wettability of the rock sample based on the first temperature sensitivity and the second temperature sensitivity.