Methods and systems for signal processing in molecular imaging. The system may include at least one storage device including a set of instructions and at least one processor in communication with the storage device. The at least one processor may obtain a first signal that is acquired by sampling, according to a first sampling frequency, an electrical signal of a detector. The at least one processor may also generate, based on the first signal and a target machine learning model, a second signal, the second signal corresponding to a second sampling frequency that is different from the first sampling frequency. The target machine learning model may specify a target mapping between the first signal and the second signal. The at least one processor may further generate an image based on the second signal.

An array substrate for a digital X-ray detector, a digital X-ray detector including the same, and a method for manufacturing the same are disclosed. The array substrate reduces a step difference of a PIN diode, removes a bent part from a lower part to reduce characteristic deterioration of the PIN diode, and increases the size of a formation region of the PIN diode to increase a fill factor. To this end, the array substrate allows a source region of an active layer included in a thin film transistor to be in surface contact with a lower electrode of the PIN diode, and disposes the lower electrode over a planarized source region or a base substrate, such that a step difference of the PIN diode is reduced and fill factor is improved.

A radiation imaging apparatus includes a pixel array in which a plurality of pixels are arrayed and a processing unit configured to process pixel signals non-destructively read out from the respective pixels. The processing unit performs a first process of obtaining image data of a plurality of frames by repeatedly reading out image data while the pixel array is irradiated with radiation, with a group of pixel signals from the plurality of pixels corresponding to image data of one frame, and a second process of generating data for a radiation image based on data differences between the image data of the plurality of frames.

Provided is a radiation detector that is capable of accurately calculating the time of occurrence of fluorescence. In addition to a configuration that calculates a single signal time, the present invention, in view of the case in which a multiple event occurs, also has a configuration that on the basis of an added signal generated by adding detection signals together, calculates the time of occurrence of fluorescence (added signal time). The radiation detector according to the present invention is configured to output the added signal time as the time of occurrence of fluorescence when the number of detection elements 3a in the fluorescence detection is plural (at the time of a multiple event). In the case of a multiple event, from the viewpoint of strengthening of a signal addition, an added signal time is more accurate than a single signal time.

The present invention relates to an X-ray imaging system. The invention further relates to an X-ray sensor to be used in such system and to a method for manufacturing such sensors. According to the invention, the combination of a lower saturation dose and obtaining a plurality of image frames during a single exposure, can be used to form a final X-ray image having an improved dynamic range.

A radiation detection apparatus can include a scintillator to emit scintillating light in response to absorbing radiation; a photosensor to generate an electronic pulse in response to receiving the scintillating light; an analyzer to determine a characteristic of the radiation; and a housing that contains the scintillator, the photosensor, and the analyzer, wherein the radiation detection apparatus to is configured to allow functionality be changed without removing the analyzer from the housing. The radiation detection apparatus can be more compact and more rugged as compared to radiation detection apparatuses that include a photomultiplier tube.

A radiation detection apparatus can include a scintillator to emit scintillating light in response to absorbing radiation; a photosensor to generate an electronic pulse in response to receiving the scintillating light; an analyzer to determine a characteristic of the radiation; and a housing that contains the scintillator, the photosensor, and the analyzer, wherein the radiation detection apparatus to is configured to allow functionality be changed without removing the analyzer from the housing. The radiation detection apparatus can be more compact and more rugged as compared to radiation detection apparatuses that include a photomultiplier tube.

A PET detecting device may include a plurality of detection modules and a processing engine. Each of the plurality of detection modules may include a scintillator array, one or more photoelectric converters, one or more energy information determination circuits and a time information determination circuit. The scintillator array may interact with a plurality of photons at respective interaction points to generate a plurality of optical signals. The one or more photoelectric converters may convert the plurality of optical signals to one or more electric signals that each include an energy signal and a time signal. The one or more energy information determination circuits may generate energy information based on the one or more energy signals. The time information determination circuit may generate time information based on the one or more time signals. The processing engine may generate an image based on the energy information and the time information.

Disclosed herein is an image sensor comprising: a plurality of packages arranged in a plurality of layers; wherein each of the packages comprises an X-ray detector mounted on a printed circuit board (PCB); wherein the packages are mounted on one or more system PCBs; wherein within an area encompassing a plurality of the X-ray detectors in the plurality of packages, a dead zone of the packages in each of the plurality of layers is shadowed by the packages in the other layers.

A radiation image capturing apparatus includes a pixel array including conversion elements arranged in rows and columns on an optically transparent substrate, signal lines that outputs a signal generated by the conversion elements and that extends in a column direction, a first scintillator disposed near a first surface of the substrate, and a second scintillator disposed near a second surface of the substrate opposite the first surface. The conversion elements include first conversion elements and second conversion elements. A light shielding layer is disposed between the first scintillator and the second conversion elements such that an amount of light that is received by the second conversion elements from the first scintillator is smaller than that received by the first conversion elements. A number of columns of the conversion elements is equal to a number of the signal lines.