A device for recording images is provided, an image-recording device and an illumination device being arranged on the same side of a specimen plane in said device. The image-recording device has illumination portions, for example individual light sources, which are actuatable independently of one another in order to be able to illuminate a specimen in the specimen plane at different angles and/or from different directions. In this way, it is possible to record a plurality of images with different illuminations, which can be combined to form a results image with improved properties.

An optical imaging system for imaging a target during a medical procedure. The imaging system includes an optical assembly including moveable zoom optics and moveable focus optics. The system includes a zoom actuator and a focus actuator for positioning the zoom and focus optics, respectively. The system includes a controller for controlling the zoom and focus actuators independently in response to received control input. The system includes a camera for capturing an image of the target from the optical assembly. The system may be capable of performing autofocus during a medical procedure.

The disclosed technology relates to an inspection apparatus that includes a stage configured to retain a specimen for inspection, an imaging device having a field of view encompassing at least a portion of the stage to view a specimen retained on the stage, and a plurality of lights disposed on a moveable platform. The inspection apparatus can further include a control module coupled to the imaging device, each of the lights and the moveable platform. The control module is configured to perform operations including: receiving image data from the imaging device, where the image data indicates an illumination landscape of light incident on the speciment; and automatically modifying, based on the image data, an elevation of the moveable platform or an intensity of one or more of the lights to adjust the illumination landscape. Methods and machine-readable media are also contemplated.

A microscope system includes an incoherent light source, a detection optical system, and an imager. The incoherent light source is a light source that emits light that is temporally not coherent. In a sample, a plurality of coherent illuminations are performed simultaneously by light emitted from the incoherent light source. The coherent illuminations are illumination by light that is spatially coherent. The direction in which the sample is irradiated with a light beam is different for each coherent illumination. In a pupil plane of the detection optical system, the respective light beams of the coherent illuminations pass through first regions different from each other. Each of the first regions satisfies the following Condition (1). At least one distance among distances between the two adjacent first regions satisfies the following Condition (2).

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Methods for imaging a sample using fluorescence microscopy, systems for imaging a sample using fluorescence microscopy, and illumination systems for fluorescence microscopes. In some examples, a method includes positioning the sample such that a plane of interest of the sample is coplanar with a focal plane of a detection objective of a microscope. The method includes positioning a paraboloidal minor around the sample such that a focal point of the paraboloidal mirror is coplanar with the focal plane of the detection objective and the plane of interest of the sample. The method includes directing a beam of annularly collimated excitation light on the paraboloidal minor to focus a disc of light on the sample and thereby to provide 360 degree lateral illumination of the sample. The method includes imaging the sample through the detection objective.

A medical/surgical microscope with two cameras configured to capture two dimensional images of specimens being observed. The medical/surgical microscope is secured to a control apparatus configured to adjust toe-in of the two cameras to insure the convergence of the images. The medical/surgical microscope includes a computer system with a non-transitory memory apparatus for storing computer program code configured for digitally rendering real-world medical/surgical images. The medical/surgical microscope has an illumination system with controls for focusing and regulating the lighting of a specimen. The medical/surgical microscope is configured for real-time video display with the function of recording and broadcasting simultaneously during surgery.

A keratometer for intra-surgery measurements mounted under a surgical microscope includes a Placido ring illuminating a patient's eye; a video camera; a beamsplitter directing a Purkinje image of the Placido ring to the video camera; a fixation light directing a beam for patient eye fixation, fixation confirmation or creating a red reflex effect to enhance IOL imaging and cataract visualization; a processor configured to determine the refractive characteristics and keratometer parameters of the patient's eye and to execute a digital image enhancement method to outline IOL features to help IOL alignment; and a digital display displaying the keratometer parameters and surgical guidance information for a surgeon.

A magnifying observation apparatus obtains a plurality of first luminance images by controlling an illumination section so as to illuminate an observation target with illumination light from a first illumination direction and controlling a change section and an imaging section so as to image the observation target, obtains a plurality of second luminance images by controlling the illumination section so as to illuminate the observation target with illumination light from a second illumination direction symmetric with the first illumination direction about an optical axis and controlling the change section and the imaging section so as to image the observation target in a plurality of different focal positions, and generates a roughness enhancement image that enhances roughness on the surface of the observation target by applying depth synthesis and roughness enhancement.

A device for deposition of particles on a target from a transparent slide having a film formed by a fluid containing suspended particles, by locally exciting the film using a laser, includes means for observing the local excitation region. The observation means comprise a sensor and a light source, the optical axes of which are substantially shared in a space between an optical splitter and the film. The optical beam of the imaging system and the optical beam of the laser are coaxially arranged in the space between the controlled optical deflection means and the film. The device comprises a first focusing optical unit arranged between the controlled optical deflection means and the film. The device comprises a second image-combining optical unit positioned between the sensor and the splitter, the sensor being positioned in the focal plane of the second optical unit.

A fluorescent microscopic imaging apparatus for detecting a skin to be tested includes a light guiding structure, a light emitting module, an imaging module and an excitation light blocking filter unit. A first plane of the light guiding structure contacts the skin to be tested. The light emitting module includes a plurality of white light emitting units and a plurality of excitation light emitting units those are staggered with each other. The imaging module is disposed at a central position of the light emitting module. The excitation light blocking filter unit blocks an excitation light with a specific wavelength emitted by each excitation light emitting unit.