A vascular filter device (1) has a support (2) for engaging the wall of a blood vessel. A filter has filter elements (5) having proximal segments (10) connected to the support (3) and distal segments at least temporarily restrained at a distal apex (7) by a holder when in a filtering closed position. At least one filter element (5) extends radially outwardly with respect to a device longitudinal axis when unconstrained. The filter element may extend in a curve with a concave portion facing radially outwardly in an unconstrained configuration.

A vascular filter system and method are disclosed. In one embodiment, the filter system comprises a dispensing needle, a guidewire and a catheter releasably attached to a filter dispenser which stores a length of filter wire. The filter wire dispenser has a guide tube which guides the filter wire into the catheter and then into a vein during surgical implantation. The filter wire is configured to form into a predetermined shape as it is deployed from the needle. The shape of the filter wire captures blood clots in the blood stream. The filter wire may be configured with a perforated section and a non-perforated section. Perforations are in fluid communication with an inner hollow lumen in the filter wire.

Implants having symmetry are described. The implant may comprise a biocompatible material and have at least two planes of symmetry, including symmetry about an equator of the implant. The implant may be a body contouring implant, wherein a posterior side of the implant is symmetric about the equator to an anterior side of the implant.

Some embodiments described herein include a heart valve replacement system that may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, a prosthetic heart valve of the system includes structural features that securely anchor the prosthetic heart valve to the site of the native heart valve. Such structural features can provide robust migration resistance. In particular implementations, the prosthetic heart valves occupy a smaller delivery profile, thereby facilitating a smaller delivery catheter for advancement to the heart.

Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

An intraluminal support structure having a delivery configuration that is a crimped open configuration to increase flexibility while maneuvering in the anatomy and having a small scarring signature.

Disclosed herein is an implantable accommodative IOL device for insertion into an eye of a patient, the device comprising an active element and a passive element. The active element has a first thickness and first refractive index, and the active element comprises an electrically responsive optical lens having variable optical power. The passive element has a second thickness and a second refractive index, and the passive element and the active element are aligned along a central axis extending perpendicularly through a central region of the device. The active element and the passive element comprise individual and separate optical lenses.

A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

Prosthetic mitral valves and their methods of manufacture and use.

A prosthetic mitral valve includes an anchor assembly, an annular strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The annular strut frame is disposed radially within the anchor assembly. An atrial end of the annular strut frame is attached to the anchor assembly such that a ventricular end of the annular strut frame is spaced away from the anchor assembly.