The described invention provides an endovascular device comprising a tube comprising a first end comprising a bifurcation and a second end comprising an opening. The bifurcation at the first end comprises a first branch and a second branch. The opening at the second end comprises a primary opening and a secondary opening. The first branch and the primary opening form a working lumen. The second branch and the secondary opening form a support lumen. The described invention further provides an endovascular device comprising a tube comprising a side-hole, a first segment comprising a primary opening and a second segment. The side-hole and the first segment form a working lumen. The second segment forms a support lumen.

An open frame prosthesis is formed with looped end terminations at its proximal and distal ends. At one end of the prosthesis, the filaments or strands are welded together in pairs to form strand couplings. A plurality of loop segments are connected to the strand couplings, one loop segment for each pair of adjacent strand couplings. In one version of the prosthesis, strands at the opposite end are bent to form looped ends. In another version, loop segments are connected to pairs of strand couplings at both ends of the prosthesis. The loop segments can be connected to the couplings by welding, fusion bonds, or tubes, which are either crimped or heat shrunk.

A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.

Disclosed is an assembly and method for implant installation between adjacent vertebral bodies of a patient. The implant has a support body and a rotatable insert therein and the support body is curved for installation between adjacent vertebral bodies transforaminally. An installation instrument is also disclosed for removable attachment to implant and engagement with the rotatable insert to selectively permit rotation between the insert and the support body. The installation instrument extends along a longitudinal tool axis and when the installation instrument is in a first position the insert is rotationally fixed with respect to the support body and when the installation instrument is in a second position the support body may rotate with respect to the insert.

An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery.

A heart valve assembly has a heart valve assembly that has an anchor section, a generally cylindrical valve support section, and a neck section that transitions between the anchor section and the valve support section. A plurality of supports extend radially outwardly in an annular manner about an upper end of the valve support section, and the anchor section has an annular flange that extends radially therefrom, so that an annular space is defined between the annular flange and the annular supports for receiving or capturing the native annulus when the heart valve is deployed. The heart valve assembly also includes a leaflet assembly having a plurality of leaflets that are stitched to the valve support section and which are positioned on an inflow side of the neck section.

The present invention provides valve prostheses adapted to be initially crimped in a narrow configuration suitable for catheterization through body ducts to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location.

A catheter device (2) is provided for implanting an anchor (9) into body tissue to attach a line (14) to the body tissue. The catheter device (2) comprises: a housing section (4), (8) extending from a distal end of the catheter device (2) along the length of the catheter device (2) toward the proximal end of the catheter device, the housing section (4), (8) comprising a distal part (8) at the distal end of the catheter device (2) and a proximal part 4 located on the proximal side of the distal part (8). An anchor deployment mechanism (106), (110) is provided at the distal part (8) of the housing section (4), (8) for deployment of the anchor (9) for attachment of the anchor (9) to the body tissue. The anchor (9) is held in its stowed position by the anchor deployment mechanism (106, 110) in the distal part (8) prior to deployment, and the anchor (9) comprises a number of hooks (62) for engagement with the body tissue and having a folded position and an unfolded position, wherein the anchor (9) is made of an elastic material such that the hooks (62) can be elastically deformed into the folded position by application of a constraining force, and will return to the unfolded position when no constraining force is applied, and wherein the hooks (62) are held in the folded position whilst the anchor (9) is in the stowed position within the distal part (8). The distal part (8) of the housing (4), (8) has a non-circular shape (118), (117) for engagement with a corresponding non-circular form (28), (108) of the anchor (9) and/or the anchor deployment mechanism (106), (110), such that when the anchor (9) is held in the distal part (8) movement of the anchor (9) is restrained with respect to rotation of the anchor (9) about a longitudinal axis of the distal part (8) due to engagement between the non-circular shape (118), (117) and the non-circular form (28), (108).

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. If desired, one or more expandable anchors may be used. The prosthesis frame, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the prosthesis frame may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. The prosthesis frame is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthesis frame expands to an expanded position such that the valve and prosthesis frame expand at the implantation site and the anchor engages the lumen wall. The prosthesis frame has a non-cylindrical configuration with a preset maximum expansion diameter region about the valve opening to maintain the preferred valve geometry. The prosthesis frame may also have other regions having a preset maximum expansion diameter to avoid blockage of adjacent structures such as the coronary ostia.

A valve prosthesis and methods for implanting the prosthesis are provided. The prosthesis generally includes a self-expanding frame and two or more engagement arms. A valve prosthesis is sutured to the self-expanding frame. Each engagement arm corresponds to a native mitral valve leaflet. At least one engagement arm immobilizes the native leaflets, and holds the native leaflets close to the main frame. The prosthetic mitral valve frame also includes two or more anchor attachment points. Each anchor attachment point is attached to one or more anchors that help attach the valve prosthesis to the heart.