An annuloplasty band and method of implantation. The band is shaped and sized to avoid the adjacent aortic valve structure and better protects against dehiscence along the muscular mitral annulus. The band is asymmetric and when implanted spans more around the side of the mitral annulus having the posterior commissure than the side with the anterior commissure. The band has a saddle shape with a posterior upward bow centered on a minor axis of the mitral annulus, and a span extending clockwise therefrom is longer than a span extending counter-clockwise. The longer span may be 150° while the shorter span extends 90°. A set of rings may have different saddle profiles and different plan view shapes for different sized bands. A method includes implanting so that the band extends over the posterior leaflet and a short distance past the posterior commissure outside of the anterior leaflet.

The present invention relates to an innovative biological prostheses, equipped with a drainage system, designed for all surgical applications where there is any risk of hematomas or seromas, which not only allows to minimize adverse events arising from its application, but allows also to improve the effectiveness of the functional reconstruction. The prosthesis of the present invention is a surgical prosthesis made of animal derived collagen having a peripheral outline and a drainage portion comprising a plurality of drainage holes which are located in one or more independent groups each of which has a regular body-centered polygon layout.

In one embodiment, a method of assembling a prosthetic valve can comprise forming a radially expandable and compressible frame by pivotally joining together a plurality of struts without requiring individual rivets. In some embodiments, the frame is formed by interweaving the struts, which can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In other embodiments, separate hinges are provided to interconnect the struts. In still other embodiments, separate flanged rivets are provided to connect the struts.

The present invention includes an embolic protection device comprising a catheter having a self-expanding embolic filter that is disposed around the catheter proximal to a distal portion, wherein the embolic filter comprises a frame, and the frame defines an opening of the embolic filter that faces the distal end of the catheter; a deployment mechanism that is disposed around at least a portion of the catheter, wherein the deployment mechanism is longitudinally movable with respect to the catheter, the deployment mechanism is configured to contain the embolic filter in a collapsed configuration, and the embolic filter is configured to self-expand upon the longitudinal retraction of the deployment mechanism; and a wire coupled to the frame for expanding the size or diameter of the embolic filter opening.

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.

An implantable prosthetic valve assembly, according to one embodiment, comprises a frame assembly including a plurality of struts and a prosthetic valve secured inside the frame assembly by sutures. At least one of the plurality of spaced struts contains at least one hole that passes from one side of the at least one strut to another side of the at least one strut and a recess disposed around the hole.

Embodiments may include an attachable fastener, which may include a bondable material that may be secured to the end of an end effector. Vibration may be tuned to occur at a distal end of the fastener. Accordingly, the fastener may be used to generate heat at a distal point of contact. If the contact surface contains bondable material, that material may be softened. If the fastener includes bondable material at the point of contact, that material may also be softened by heat produced by vibration at the contact area. A hard implant or another polymeric material may function as the anvil.

A stent comprises an elastically deformable stent wall forming a lumen extending between a first opening and a second opening of the stent. The stent wall is configured to be percutaneously delivered into a blood vessel, secure to a blood vessel wall of a blood vessel, and radially expand from a first configuration to a second configuration within the blood vessel into direct contact with the blood vessel wall. The first configuration defines a first major dimension, a first minor dimension, a first cross-sectional area, a first cross-sectional shape, and a first perimeter of the stent wall. The second configuration defines a second major dimension, a second minor dimension that is greater than the first minor dimension, a second cross-sectional area that is greater than the first cross-sectional area, and the first perimeter of the stent wall.

A device for reducing heart valve regurgitation including a plug for placing between natural heart valve leaflets, the plug shaped so that, upon systole, the natural heart leaflets coapt upon the plug, a frame attached to the plug by a bridging element, for supporting the plug between the natural heart valve leaflets, the frame having at least one dimension in a plane of the heart valve annulus which is wider than the diameter of the heart valve annulus, and a plurality of anchors attached to the device, for preventing the device from being swept upstream of the heart valve annulus upon systole. Related apparatus and methods are also described.

A method for treatment or prevention of diseases accompanying abnormal growth of a body organ or mass. Specifically, a method of manufacturing a capsule device to encase a body organ such as kidney, liver and ovary is provided. Abnormal growth of a body organ is slowed or halted by covering the body organ such as kidney, liver and ovary. The diseases associated with abnormal growth include, for example, polycystic kidney disease and polycystic liver disease.