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A
HUMAN NECESSITIES
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A61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
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A61F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
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A61F2310/00389
The prosthesis being coated or covered with a particular material
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A61F2310/00592
Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
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A61F2310/00916
Coating or prosthesis-covering structure made of compounds based on metal sulfides
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A61F2310/00916

SURFACE MODIFICATION METHOD AND STRUCTURE FOR IMPROVING HEMOCOMPATIBILITY OF BIOMEDICAL METALLIC SUBSTRATES
20170065748 · 2017-03-09 ·

The present invention relates to a surface modification method for improving the hemocompatibility of biomedical metallic substrate, comprising: fixing a sulfur-containing monomolecular film on the surface of oxide layer of a biomedical metallic substrate by molecular self-assembly. The surface modification will improve the hydrophilicity and hemocompatibility of the biomedical metallic substrate in contact with the blood, and ensure that the biomedical metallic substrate is non-toxic to the endothelial cells.