An isotope production device may include a reactor core configured to contain an aqueous fuel solution. The device may further include shielding material substantially surrounding the reactor core. The device may also include a heat exchanger positioned above the reactor core. The device may further include a flow path extending between the heat exchanger and a bottom of the reactor core. The device may also include an extraction device positioned along the flow path at a position after the heat exchanger, the extraction device configured to extract a portion of the aqueous fuel solution after the heat exchanger. The device may further include an orifice plate coupled to the bottom of the reactor core.

An isotope production device may include a reactor core configured to contain an aqueous fuel solution. The device may further include shielding material substantially surrounding the reactor core. The device may also include a heat exchanger positioned above the reactor core. The device may further include a flow path extending between the heat exchanger and a bottom of the reactor core. The device may also include an extraction device positioned along the flow path at a position after the heat exchanger, the extraction device configured to extract a portion of the aqueous fuel solution after the heat exchanger. The device may further include an orifice plate coupled to the bottom of the reactor core.