A fluid sampler system includes a fluidic head including a gas aperture capable of communication with a pressurized gas source, a liquid conduit capable of communication with a sample reservoir, and a seal capable of forming a compression seal to the sample reservoir when gas pressure is applied to the sample reservoir through the gas aperture and capable of displacing a portion of the sample through the liquid conduit; and a positioning apparatus capable of positioning the fluidic head and the sample reservoir in communication with one another. A method for providing an aliquot of sample, includes forming a releasable compression seal to a reservoir including a liquid sample; pressurizing the reservoir with compressed gas; displacing an aliquot of the sample from the reservoir; and transferring the displaced aliquot of the sample to a location.

The invention encompasses compositions and compounds for inhibiting CoV2 Spike GP and human ACE2 proteins and a 3D pharmacophore model described herein provides the means for rapid, high-throughput virtual screening of potential anti-CoV2 modulators thus facilitating, optimizing and speeding up the search for the discovery of a potent anti-COVID-19 agent and methods of treatment and prevention thereof.

A wastewater sampling system including: an inlet tube; an outlet port; a high-flow circuit fluidly coupling the inlet tube to the outlet port; a first pump, along the high-flow circuit, configured to pump wastewater through the high flow circuit; a sampling circuit, fluidly coupled to the high-flow circuit via a junction, comprising a solid waste filter fluidly coupled to the junction and a solid-phase extraction cartridge fluidly coupled to an outlet of the solid waste filter; a second pump along the sampling circuit; a controller configured to, during a sampling cycle at a first time, activate the first pump; at a second time, activate the second pump; and at a third time succeeding the second time by a sampling duration, deactivate the second pump.

A robot accessory and/or device that provides a sample collector device, a sample storage device, and a work surface. Upon activation, the sample collector device performs a full cycle in which an actuator causes the movement (i.e., extension and then retraction) of an actuator arm that simultaneously causes the top link plate, the lance plunger, the plunger guide, and the plunger to likewise move, including the depression and/or compression and release of the pipette. During this full cycle, this single device is able to remotely collect solid, liquid and/or multiphase samples of potentially hazardous materials and reduces human exposure to this hazardous material and dangerous environment.

The present invention provides methods and diagnostic kits for the detection or prediction of SARS-CoV-2. More particularly, the present invention provides for the diagnosis of SARS-CoV-2 by detecting in a human biological sample inhibition of protein translation by the phosphorylation of the eukaryotic initiation factor-2α (eIF-2α), and the formation of stress granules (SGs) known to be affected by Sars-CoV-2

The invention encompasses an innovative system for exosome-based diagnostics of infection and/or inflammation that is based on a novel exosome isolation kit from biological fluids such as urine and saliva in the form of a syringe, and a rapid diagnostic test device that simultaneously detects exosomal biomarkers based on a quantitative assay and disease (infection/inflammation) biomarkers.

This portable air sampling apparatus includes a Venturi pump creating a vacuum in a suction inlet when compressed air circulates therein; a supply line supplying the Venturi pump with compressed air, including an electrovalve that controls circulation of compressed air in the supply line; a suction line to suction an air sample, having an air circulation member delimiting a chamber for removably receiving a substrate for capturing odorous molecules and suitable for circulating the suctioned air sample through the substrate; and an electronic unit, connected to the electrovalve, controlling its opening and closing so when the electrovalve is opened, compressed air circulates in the supply line through the electrovalve, while when the electrovalve is closed, compressed air circulation in the supply line, between upstream and downstream of the electrovalve, is interrupted by the electrovalve. This enables performing reliable inspections, while being practical and easy to use.

Systems and methods for analysing a fluid including a fluid sample delivery application. The system includes a sensing element configured to respond to at least one analyte in a sample of fluid. A detector is provided, configured to sense the response to the analyte by the sensing element. The fluid sample delivery apparatus includes a dosage needle configured to deliver the sample of fluid to the sensing element, at least one pump configured to control flow of fluid through the dosage needle, and at least one actuator configured to move the dosage needle relative to the sensing element. At least one controller is provided, configured to control the at least one pump and the at least one actuator.

A flow cytometer module configured to be integrated with a liquid handling system is provided herein. The flow cytometer module includes (a) a flow cell, (b) a first fluidic pathway, (c) an inlet configured to receive a sample introduction device of the liquid handling system including one or more samples, (d) a second fluidic pathway in fluid communication with the first fluidic pathway, (e) a laser interrogation device configured to examine the one or more samples at a laser interrogation point in the second fluidic pathway, and (f) a controller in communication with the liquid handling system and configured to cause the flow cytometer module to perform functions comprising: (i) recording data from the laser interrogation device corresponding to a plurality of events as the one or more samples pass the laser interrogation point, and (ii) transmitting the data corresponding to the plurality of events to the liquid handling system.

A biological sample processing device includes a containing bottle. A receiving opening is provided and a liquid outlet is provided. The device further includes an upper cover assembly and a lower cover. The upper cover assembly is connected to the upper end of the containing bottle. The lower cover is connected to the lower end of the containing bottle. The upper cover assembly includes an upper cover, a lower seal, a piston and a puncturing element. The upper cover is provided with a through hole, and the lower seal is disposed at a lower end of the through hole. The piston is closely matched with an inner wall of the through hole and can slide along the inner wall to drive the puncturing element to pierce the lower seal. The disclosure provides advantages that the biological sample can be processed by the provided device without opening the upper cover.