G01N2001/149

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION

Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

Syntactic Foams as Mechanically-Triggered Capture Vehicles
20210262904 · 2021-08-26 ·

Syntactic foams are materials including hollow microspheres distributed throughout a cured polymeric resin. Hollow microspheres within syntactic foams, including collapsible shells that enclose empty cavities, can serve as receptacles to capture environmental constituents upon applied temperature and pressure. An epoxy formulation including of EPON™ 828, HELOXY™ 61, and TETA was combined with hollow glass microspheres with isostatic crush strengths of 300, 3000, and 10,000 psi. Effects of pressure and temperature on the mechanical properties were evaluated via dynamic mechanical analysis. Storage modulus and glass transition temperature depended on formulation. Upon exposure to specific temperature and pressures, the hollow glass spheres embedded within the resin lose mechanical integrity and collapse, resulting in the generation of unencapsulated void spaces, primed to capture embedded liquid. Controllable loss of mechanical integrity enables syntactic foams to serve as on-demand receptacles to retain constituents in the surrounding environment, resulting from externally triggered pressures and temperatures.

Materials transport device for diagnostic and tissue engineering applications

Devices that can transport biological materials are described. The devices incorporate capillary channeled fibers that can effectively transport living cells as well as other biological materials such as nutrients, growth factors, waste materials, etc. The devices can include a sorptive material at one end of the fibers that can improve transport of materials through the devices. The devices can differentially transport different cell types, particularly when the fibers are held in a vertical orientation. Diagnostic devices that incorporate the capillary channeled fibers are described that can be utilized to separate cell types from one another. Tissue engineering scaffolds that incorporate the capillary channeled fibers are described that can more efficiently transport materials into and out of the scaffolds.

Specimen collection device, holder for specimen collection device, and specimen pre-processing method that uses specimen collection device

This specimen collection device has a channel through which a specimen can be drawn by capillarity. The channel has two channel sections that extend from the tip side to the base side and are connected at the tip side. One of the channel sections is connected to a base side specimen intake port, and the other terminates at a location prior to reaching the base end. An air hole is provided at this terminating location. The specimen collection device is equipped with an extraction unit for collecting a prescribed amount of the specimen. The extraction unit includes the two channel sections on the tip side of the air hole, and can be severed from the other sections of the device body of the specimen collection device via a severable section.

DEVICES AND METHODS FOR COLLECTING AND STORING FLUID SMAPLES FOR ANALYSIS

A sampling device for collecting, storing and processing fluid samples for analysis is disclosed. The sampling device comprises a porous polymer monolith sampling substrate housed within a substantially impermeable housing. The housing surrounds the sampling substrate and further comprises a sampling aperture via which the sampling substrate is accessible externally from the sampling device.

KETONE BODY SENSING DEVICE AND METHOD
20210003564 · 2021-01-07 ·

Devices, patch sensors, and methods for detecting a ketone body are disclosed. An exemplary device includes a collection apparatus for collecting a sample amount of interstitial fluid and a ketone body indicator having an initial negative state and having a positive state when at least a threshold value of the ketone body is collected in the sample amount.

SYSTEMS AND METHODS FOR FLUID SAMPLE COLLECTION AND TESTING

A fluid sample testing apparatus has a fluid collector tube and a fluid collector in fluid communication with a sample holding container. The fluid collector is inserted into and penetrates the fluid collector tube and pressure is generated to release fluid from the fluid collector into the sample holding container, and air passes outside of the apparatus from the fluid collector tube via a vent path. The vent path is sealed with the fluid collector is fully inserted into the fluid collector tube. Indicator or test strips are optionally included in a stem of the fluid collector.

Systems, devices, and methods for bodily fluid sample collection

Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

APPARATUS FOR SOLID PHASE MICROEXTRACTION
20200355587 · 2020-11-12 ·

The present disclosure provides an apparatus for sampling at least one analyte from a sampling fluid. The apparatus includes: a solid-phase microextraction (SPME) sampling instrument. A connector is attached to the SPME sampling instrument and is coupleable to an aerial drone. The apparatus includes a protective cover that is sized and shaped to at least partially surround the SPME sampling instrument. The SPME sampling instrument and the protective cover are movable in relation to each other between a protecting configuration and a sampling configuration. The SPME sampling instrument and the protective cover are (i) biased in the protecting configuration when the density of the fluid surrounding the SPME sampling instrument is less than the density of the sampling fluid; and (ii) biased in the sampling configuration when the density of the fluid surrounding the SPME sampling instrument is equal to or greater than the density of the sampling fluid.

System and Method for Qualitative and Quantitative Detection of Substance on Surfaces
20200340963 · 2020-10-29 ·

A surface wipe for the detection of harmful substances on surfaces by producing uniform color change and a color comparator to determine the concentration of harmful substance collected on the wipe by comparing the intensity and hue of the uniform color on the wipe to a calibrated color scale related to specific concentration of the target harmful substance. In operation, the wipe is held from the handle to swipe a suspect surface. The pressure applied by fingers at certain areas on the rigid or flexible top support member of the wipe during the swiping process is transferred to the flexible wipe body. The flexible body of the wipe uniformly distribute the pressure applied by fingers throughout its mass and/or take the shape of irregular and uneven surface allowing the collection and color forming assembly to produce uniform color change that can be quantified by the color comparator.