G01N2021/396

VIRUS SENSING IN EXHALED BREATH BY INFRARED SPECTROSCOPY
20210208062 · 2021-07-08 ·

Techniques for detecting cannabinoid, opioid, and virus aerosols in an exhaled breath are provided. An example method of identifying a virus-containing aerosol in exhaled breath includes capturing a breath input in an aerosol filter cartridge, disposing the aerosol filter cartridge in an optical path in a spectroscopy system, detecting one or more infrared spectral features of the breath input with the spectroscopy system, and identifying the virus-containing aerosol based on the one or more infrared spectral features.

BIOCIDE DETECTION

A method and kit for the detection of biocide levels in a fluid conducting and containment system. Using micelle formation in the presence of a marker solution to determine if a biocide is at its effective dose throughout a fluid conducting and containment system.

TERAHERTZ SPECTRUM TEST DEVICE AND SYSTEM
20200209154 · 2020-07-02 ·

A terahertz spectrum test device and system includes a femtosecond fiber laser configured to generate a pump light and a probe light. The pump light excites a terahertz transmitter to generate terahertz waves which are transmitted to a sample suspension device to irradiate a suspended to-be-tested sample, and the probe light is directly transmitted to a terahertz detector. The terahertz detector receives the terahertz waves transmitted from the sample suspension device, and then transmits the terahertz waves and the probe light together to a signal processing circuit to obtain a corresponding terahertz time-domain spectrum. By adoption of the terahertz spectrum test device and system, the to-be-tested sample need not be fixed with a clamp or other instruments, so that terahertz waves will not irradiate to the instrument used for fixing the to-be-tested sample during a terahertz spectrum test, which may otherwise affect the test result.

Techniques for rapid detection and quantitation of volatile organic compounds (VOCs) using breath samples

An exemplary breath analysis system may include a sampling chamber having a molecule collector disposed therein. The molecule collector may be configured such that volatile organic compounds (VOCs) present in a breath sample introduced to the sampling chamber adhere to the molecule collector. A photodiode array configured to excite and/or heat the molecule collector to release at least a portion of the VOCs from the molecule collector to release at least the portion of the VOCs adhered to the molecule collector. An analysis device (e.g., a mass spectrometer or Terahertz (THz) spectrometer) may identify one or more target VOCs from among at least the portion of the VOCs released from the molecule collector and generate an output representative of the identified target VOC(s). The output may include information that quantitates a concentration of the target VOC(s) with respect to a source of the breath sample.

CARBON ISOTOPE ANALYSIS DEVICE AND CARBON ISOTOPE ANALYSIS METHOD

A carbon isotope analysis device including a carbon dioxide isotope generator provided with a combustion unit that generates gas containing carbon dioxide isotope from carbon isotope, and a carbon dioxide isotope purifying unit; a spectrometer including an optical resonator having a pair of mirrors and a photodetector that determines intensity of light transmitted from the optical resonator; and a light generator including a light source, a splitter that splits light from the light source, a focusing lens that focuses light from the splitter, and a mirror that reflects light from the focusing lens and sends the light back to the light source via the focusing lens and the splitter. A carbon isotope analysis device improved in stability of a light source and a carbon isotope analysis method by use of the analysis device are provided.

METHODS AND SYSTEMS FOR ANALYZING TISSUE QUALITY USING MID-INFRARED SPECTROSCOPY

A method of evaluating the quality state (such as a fixation status) of a cellular sample is provided. A MIR spectrum (220) of the sample is obtained, and a classification (211) or quantification (231) algorithm is applied to the MIR spectrum to identify features (221) indicative of the quality state and/or to classify the sample. The quality state may then be used to determine whether the sample is appropriate for an analytical method and/or whether remedial processing (such as further fixation) is appropriate.

Product inspection method and product inspection apparatus

Super continuum light having a continuous spectrum over at least 1100 to 1300 nm is emitted from a pulsed light source, is pulse-stretched by a stretching element such that a relationship between a wavelength and an elapsed time in one pulse is one to one, and is radiated to a product. The light transmitted through the product is received by a light receiver, and output data is input to the determination unit. A quality determination program of the determination unit calculates an absorption spectrum from the output data, quantifies the absorption spectrum by chemometrics, and compares the absorption spectrum with a reference value to determine quality. The product determined to be a defective product is excluded by an exclusion mechanism.

OPTICAL DEVICE HAVING A TRIGGER UNIT, TRIGGER UNIT, AND METHOD FOR CAPTURING INFRARED ABSORPTION SPECTRA

An optical device includes a tunable laser for repeatedly irradiating a sample with laser light as wavelength scans over a defined wavelength range, a trigger unit and a data acquisition unit. The laser outputs at least a first trigger signal and a second trigger signal. The first trigger signal outputs a temporal start and a temporal end of a wavelength scan, and the second trigger signal comprises a pattern of scanning pulses distributed over the tunable wavelength range at predefined wavelength intervals. The trigger unit has an adder which adds the trigger signals and a mixer which mixes the trigger signals with the reference signal to form the trigger output signal. A method for capturing infrared absorption spectra is also provided.

ANALYSIS APPARATUS AND ANALYSIS METHOD

The present invention relates to an analysis apparatus adapted to analyze a measurement target component contained in a sample by irradiating a measurement cell into which the sample is introduced with pulse-oscillated light, whereby suppressing reduction in wavelength resolution without shortening the pulse width. The analysis apparatus includes multiple light sources adapted to produce pulse oscillations, a light detector adapted to detect light emitted from the light source and transmitted through the measurement cell, and a signal separation part adapted to separate, from a light intensity signal obtained by the light detector, signals corresponding to a part of pulses from the light sources.

Gas Detection Device and Gas Detection Method

In a gas detection device and a gas detection method of the present invention, detection target gas is detected on the basis of reflected light of detection light (sensing light) frequency-modulated with respect to a center frequency and a distance to an object that generates the reflected light is measured. In the gas detection, an output signal of a light reception unit for receiving the reflected light is subjected to phase-sensitive detection. A synchronous detection timing of this phase-sensitive detection is adjusted on the basis of the measured distance to the object.