Disposable, pre-sterilized, and pre-calibrated, pre-validated sensor components are provided. The sensor components interact with a sensor system having disposable fluid conduit or bioreactor bag and a reusable sensor assembly. The components can include an optical bench or inset optical component or module designed to be integrated within the disposable fluid conduit or bioreactor bag, which provides an optical light path through the conduit or bag. The sensors systems are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the disposable fluid conduit or bag and on the reusable sensor assembly. Methods for calibrating the sensor and for determining a target property of an unknown fluid are also disclosed. The devices, systems and methods relating to the sensor are suitable for and can be outfitted for turbidity sensing.

Disposable, pre-sterilized, and pre-calibrated, pre-validated sensor components are provided. The sensor components interact with a sensor system having disposable fluid conduit or bioreactor bag and a reusable sensor assembly. The components can include an optical bench or inset optical component or module designed to be integrated within the disposable fluid conduit or bioreactor bag, which provides an optical light path through the conduit or bag. The sensors systems are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the disposable fluid conduit or bag and on the reusable sensor assembly. Methods for calibrating the sensor and for determining a target property of an unknown fluid are also disclosed. The devices, systems and methods relating to the sensor are suitable for and can be outfitted for turbidity sensing.

A method and system for optical vortex transmissometry. The method uses optical orbital angular momentum (OAM) and optical vortices to discriminate coherent non-scattered light from incoherent scattered light. The system includes a laser which transmits a Gaussian laser beam through a medium. An OAM generating device is placed before a photodetector receiver. Coherent, non-scattered light passing through the OAM generating device forms an optical vortex, used to discriminate against the unwanted scattered signal that does not form a vortex. Alternatively, the system includes a transmitter, which generates one or more OAM modes, which are transmitted through a turbid medium. At the receiver, an OAM detection device analyzes the OAM mode spectrum of the received light. Coherent non-scattered light retains the OAM encoded at the transmitter, while scattered light does not. The attenuation of the channel is determined by comparison of the received OAM mode spectrum relative to the transmitted OAM mode spectrum.

A method of operating a detection system includes switching the system from a normal mode for sensing smoke to a high sensitivity mode for sensing airborne particles, such that in the high sensitivity mode the detection system is configured to discriminate between particles of diameters less than 2.5 micrometers and 10 micrometers. Transmitting light from one or more light sources of the detection system into a monitored space, and detecting scattered light at one or more light sensing devices of the detection system. The detection of scattered light is indicative of one or more indoor air quality conditions in the monitored space.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

Provided is a flocculation state monitoring sensor with which blockage of an ejecting part which ejects a gas towards a light emitting part and a light receiving part can be prevented, and which performs stable monitoring. A flocculation state monitoring sensor comprising: a light emitting part which irradiates laser light towards a measuring region which measures a flocculation state; and a light receiving part which receives light scattered along a direction which intersects with a direction along an optical axis of said light emitting part, wherein the light emitting part and the light receiving part are cleaned by air being ejected from nozzles theretowards. A small amount of air is provided to the nozzles between cleaning periods to purge floc, etc.

A measuring apparatus includes a flow cell through which a sample containing particles flows, a light source for irradiating light on the sample flowing through the flow cell, a fluorescence detector for detecting the fluorescence generated from the sample irradiated with light from the light source, and a control unit for flowing a positive control sample containing a fluorescent dye through the flow cell, measuring the fluorescence generated from the positive control sample irradiated by the light from the light source via the fluorescence detector, comparing the obtained measurement value and a reference value, and adjusting the detection sensitivity of the fluorescence detector according to the comparison result.

Light detection systems for simultaneously measuring scattered light (e.g., in a flow stream) from particles having diameters which differ by 100 nm or more are described. Light detection systems according to certain embodiments include a static optical adjustment component, a variable optical adjustment component and a photodetector. Systems and methods for measuring scattered light from a sample (e.g., in a flow stream) and kits having a static optical adjustment component, a variable optical adjustment component and a photodetector are also provided.

A process tube device can detect the presence of any external materials that may reside within a fluid flowing in the tube. The process tube device detects the external materials in-situ which obviates the need for a separate inspection device to inspect the surface of a wafer after applying fluid on the surface of the wafer. The process tube device utilizes at least two methods of detecting the presence of external materials. The first is the direct measurement method in which a light detecting sensor is used. The second is the indirect measurement method in which a sensor utilizing the principles of Doppler shift is used. Here, contrary to the first method that at least partially used reflected or refracted light, the second method uses a Doppler shift sensor to detect the presence of the external material by measuring the velocity of the fluid flowing in the tube.

A spatial gradient-based fluorometer featuring a signal processor or processing module configured to: receive signaling containing information about light reflected off fluorophores in a liquid and sensed by a linear sensor array having a length and rows and columns of optical elements; and determine corresponding signaling containing information about a fluorophore concentration of the liquid a fluorophore concentration of the liquid that depends on a spatial gradient of the light reflected and sensed along the length of the linear sensor array, based upon the signaling received.