Patent classifications
G01N21/534
Methods and systems for point-of-care coagulation assays by optical detection
This invention relates to an optical system and method for performing turbidity assay, e.g. coagulation of blood or plasma, comprising a standard optical reference, a sample handling structure, a light source and an optical detection unit. The standard optical reference, such as a fluorophore-doped glass, provides constant optical signal under controlled optical conditions. The sample handling structure, such as a microfluidic system with reaction chamber, can be placed beneath or above the standard optical reference. During operation, the coagulating plasma/blood changes its optical absorbance and reflection properties, which results in changes in optical signal that reaches the optical reading unit. The variation of the optical signal, such as fluorescence signal indicates the kinetics of the turbidity varying process, such as plasma/blood coagulation process. This invention is used for performing turbidity assay with optical system, including photometry system, fluorescence system, Raman Spectroscopy system and so on.
MONITORING OPACITY OF SMOKE EXHAUSTED BY WOOD STOVE AND CONTROLLING WOOD STOVE BASED ON SAME
A wood stove monitoring and control device can include a mounting flange mountable to a chimney exhaust pipe of a wood stove. The device can include a ring removably mountable on top of the mounting flange, where the flange is suitably positioned vertically along the exhaust pipe so that the ring is positioned at least partially above an end of the exhaust pipe. The device includes an optical beam source disposed on the ring, and which generates and outputs an optical beam. The device includes an optical sensor positioned on the ring opposite the optical beam source to detect the optical beam output by the optical beam source as the optical beam passes through smoke exhausted by the wood stove through the exhaust pipe. The device can include a temperature probe disposed on the ring to measure a temperature of heat exhausted by the wood stove through the exhaust pipe.
Turbidity sensor and water-bearing domestic appliance equipped therewith
A turbidity sensor for a water-bearing domestic appliance includes a sensor housing having a housing main part and two housing projections protruding from the housing main part side by side and at a distance from one another, where the two housing projections delimit between them a measuring channel for a liquid to be measured. One of the housing projections emits a measuring light beam along a measuring path which runs transversely through the measuring channel to the other housing projection. The measuring path crosses the measuring channel in the channel longitudinal direction remote from a point of smallest channel width of the measuring channel or the measuring channel has a constriction at a longitudinal distance from its longitudinal midpoint, at which constriction the channel width is smaller than in a region of a longitudinal midpoint.
System and method for characterization of inclusions in liquid samples
Described are systems and methods for optical characterization of inclusions, such as solids and liquids, in liquid samples. An inclusion characterization system may include a radiation source, a radiation detector, a sample optical cell, and a sample delivery mechanism. The radiation detector may be configured to perform time resolved measurements. The sample may be delivered to the sample optical cell by the sample delivery mechanism at a flow rate set for preserving the sample integrity (i.e., the transport rate). The inclusion characterization in the sample may be performed at flow rates set for sample analysis (i.e., the analysis rate). The analysis rate may differ from the transport rate. The rate difference may be achieved by diverting only a portion of the overall sample into the sample optical cell. Also provided are examples of disengagement of sample transport and analysis flow rates.
MODULAR OPTICAL SENSOR
An optical sensor may include a housing, a printed circuit board, an optical emitter, and an optical detector. The housing can define a channel configured to receive a transparent tubing line through which fluid can flow during operation. The housing can have multiple optical pathways, including a primary optical pathway transecting the channel, a light emission optical pathway, and a light detection optical pathway. The optical emitter and optical detector can each be mounted on the printed circuit board. Further, the housing may be positioned on the printed circuit board with the optical emitter aligned to emit light into the light emission optical pathway and the optical detector aligned to receive light from the light detection optical pathway.
Monitoring opacity of smoke exhausted by wood stove and controlling wood stove based on same
A wood stove monitoring and control device can include a mounting flange mountable to a chimney exhaust pipe of a wood stove. The device can include a ring removably mountable on top of the mounting flange, where the flange is suitably positioned vertically along the exhaust pipe so that the ring is positioned at least partially above an end of the exhaust pipe. The device includes an optical beam source disposed on the ring, and which generates and outputs an optical beam. The device includes an optical sensor positioned on the ring opposite the optical beam source to detect the optical beam output by the optical beam source as the optical beam passes through smoke exhausted by the wood stove through the exhaust pipe. The device can include a temperature probe disposed on the ring to measure a temperature of heat exhausted by the wood stove through the exhaust pipe.
Portable multi-spectrometry system for chemical and biological sensing in atmospheric air
The invention relates to a portable multi-spectrometry system for chemical and biological sensing in atmospheric air. A portable, spectrometric system integrates multiple spectroscopy theories, combines their advantageous features, and fills the gaps for their limitations. The combined spectrometry system with operations for PLS, IRAS, MAS, MFS, RSS, and MS, will detect particles and chemicals, directly and sequentially, in the same air-stream.
METHOD FOR DETERMINING THE SENSITIVITY OF A BACTERIAL STRAIN TO A BACTERIOPHAGE
Method for determining the sensitivity of a bacterial strain of interest to a viral strain of bacteriophages, the method comprising: a) preparing a sample, this comprising bringing bacteria, belonging to the bacterial strain of interest, into contact with bacteriophages, each bacteriophage belonging to the same viral strain, the bacteria being either in a liquid medium, or in an agar medium; b) placing the sample between a light source and an image sensor, the light source emitting a light wave in an emission spectral band comprised between 500 nm and 600 nm; c) illuminating the sample using the light source and acquiring at least one image of the sample, with the image sensor, in the emission spectral band, no image-forming optic being placed between the sample and the image sensor; d) on the basis of the acquired images, determining a sensitivity of the bacterial strain of interest to the viral strain.
STABLE MEASUREMENT OF SENSORS, METHODS AND SYSTEMS
Gain independent reference channel measurement system and method. A method of making robust, stable measurements, in a variety of different applications is disclosed. More specifically, this disclosure describes systems and methods relating to performing gain independent reference channel measurements by making two phase measurements of a device under test. Mathematically, the measurements are combined and many common mode parameters drop out. The result yields an analysis of a device under test analysis which mitigated errors, predominately arising from environmental variations and changes in circuit behavior stemming from swings in signal input.
DETECTION AND MONITORING OF DOSAGE DELIVERY FOR VAPORIZED WAXES, SOLIDS OR VISCOUS OILS, AND CANNABINOIDS
A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.