A system for measuring the blood loss comprises a measuring device that determines the hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, the hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

Devices for monitoring a bioreactor are configured for in-situ or ex-situ analysis. Noise from polarization dependent loss is addressed with a polarizer and reference photodetector for detecting a swept wavelength signal from a tunable laser spectrometer after transmission on a optical fiber but before a sample detection region.

A system for measuring the blood loss comprises a measuring device that determines a hemoglobin concentration of fluid within a container utilizing a light source and a light detector. The container receives blood and other fluids from a patient during a medical procedure. Light from the light source is passed through the blood and other fluids in the container and is detected by the light detector. Based upon a magnitude of light detected, a hemoglobin concentration of the fluid in the container can be determined. A volume-measuring device determines the volume of blood and fluid in the container. Knowing the hemoglobin concentration and volume of fluid in the container, the volume of patient blood loss in the container can be determined. The blood loss measuring device in combination with infusion systems maintains a real-blood volume status so that proper infusion of blood, crystalloid and/or colloid solutions occurs.

A multicore optical fiber includes a cladding and multiple cores disposed in the cladding. Each core has a light-guiding path and follows a helical trajectory about a fiber axis. The multicore fiber also includes a set of discrete lateral coupling zones, which are longitudinally distributed and azimuthally aligned with respect to the fiber axis. Each lateral coupling zone forms an optical coupling path, which enables at least one of lateral in-coupling and out-coupling of light between a corresponding one of the cores and an exterior of the multicore fiber. An optical probing system for light delivery to and/or light collection from a probed region includes a multicore optical fiber to enable coupling of guided light out of the cores for delivery to the probed region and/or collection of light from the probed region for coupling into one of the cores.

A multicore optical fiber includes a cladding and multiple cores disposed in the cladding. Each core has a light-guiding path and follows a helical trajectory about a fiber axis. The multicore fiber also includes a set of discrete lateral coupling zones, which are longitudinally distributed and azimuthally aligned with respect to the fiber axis. Each lateral coupling zone forms an optical coupling path, which enables at least one of lateral in-coupling and out-coupling of light between a corresponding one of the cores and an exterior of the multicore fiber. An optical probing system for light delivery to and/or light collection from a probed region includes a multicore optical fiber to enable coupling of guided light out of the cores for delivery to the probed region and/or collection of light from the probed region for coupling into one of the cores.

A transverse optical transmission probe having a probe body and a probe tip. The probe use optical fibers to both transmit radiation from an instrument to the probe tip and to return the sample affected radiation to the instrument. The fibers are in parallel and contained in the probe body. The probe tip includes two optical elements that protrude into the sample and are configured to define a sample gap so that incident radiation pass through the sample in a direction transverse to the axis to the probe and eventually reaches the receiving fiber. Each of the optical elements may be formed from a single piece of material or may be a composite formed by adhering two or more pieces of material together. One or more lensed surfaces may be used to cause the end of the transmitting fiber to be imaged on the end of the receiving fiber.