G01N21/9027

Systems and Methods for Identifying Protein Aggregates in Biotherapeutics
20190154560 · 2019-05-23 · ·

Systems and methods for inspecting particles in a liquid beneficial agent are provided. Inspecting particles in a liquid beneficial agent includes selectively illuminating at least a portion of a liquid beneficial agent contained within a container using an excitation beam configured to excite photoluminescent particles in the liquid beneficial agent to emit an emission light and produce scattered excitation light, filtering the illuminated portion of the liquid beneficial agent to transmit the emission light and block the scattered excitation light, obtaining an image of the filtered emission light, analyzing image data representing the image of the filtered emission light to detect regions of the image representing the intrinsic photoluminescence of the photoluminescent particles, measuring an intensity of the regions of the image representing the intrinsic photoluminescence of the photoluminescent particles, and determining a size or number of the photoluminescent particles from the measured intensity of the regions.

Device and method for testing and inspecting integrity of a container

An inspection device and method for testing and inspecting integrity of a container (200) is disclosed. The inspection device has an angled member (102) and a viewing member (104) secured to the angled member. Together, the angled and viewing members are configured to hold a container to be analyzed. The inspection device also includes a cradle (106) secured to the angled member, the cradle including a cavity (108) configured to hold the angled member at an angle. The inspection device also includes a light source holder (110) secured to the viewing member, a leg member (112) extending from the light source holder, and at least one light source (114) extending through the light source holder. The light source has a first end extending outwardly from the light source holder and a second end extending within the light source holder from which light projects. The light from the light source is projected toward the viewing member. The viewing member includes at least one viewing window (105). A lens is located between the second end of the light source and the viewing member, and a filter is located between the lens and the viewing member.

Wrapper for terahertz, detection sensor, detection apparatus using terahertz wave, optical identification device for terahertz, apparatus for recognizing optical identification device for terahertz wave, and writing apparatus for identification unit

A wrapper for a terahertz wave according to an embodiment of the present invention includes: a terahertz wave transmission layer that is made of a material that transmits a terahertz wave; and an electric field enhancement structure that enhances an electric field by reacting with a predetermined frequency band of terahertz waves passing through the terahertz wave transmission layer. An optical identification device for a terahertz wave according to an embodiment of the present invention includes m identification units composed of: a terahertz wave transmission layer that is made of a material that transmits a terahertz wave; and a waveguide grating that resonates at a natural resonant frequency when receiving the transmitted terahertz wave, in which the natural resonant frequency is any one of a first natural resonant frequency to an n-th natural resonant frequency.

Method of preventing lamellar silica formation in glass container
12042830 · 2024-07-23 · ·

Methods of preventing the formation of lamellar silica formation in a borosilicate glass container storing a pharmaceutical formulation in an interior of the glass container in accordance with embodiments of the disclosure can include washing the container and drying the container under extended dry conditions of at least 3000 ms.

SAMPLE TRANSPORT MEDIUM VIAL
20240226897 · 2024-07-11 ·

Provided is a sample transport medium vial, which may include: a sample collection part having an extraction part formed at the front end thereof, having a handle part formed in the middle thereof, and having, at the rear end thereof, a push button that can be pressed with the fingers; a medium accommodation tube in which a medium accommodation space capable of accommodating the medium is formed, and which is formed in a shape that encompasses the extraction part so that the extraction part of the sample collection part can be protected; and a one-touch-type elastic push device, which is provided at the handle part so that the protrusion length of the extraction part from the handle part can be extended to a first length or contracted to a second length when a collector presses the push button once or twice.

System and Method for Inspecting a Transparent Cylinder
20190056335 · 2019-02-21 ·

An inspection system for detecting a particle in a transparent cylinder having a longitudinal axis and a diameter includes a light source able to illuminate a transparent cylinder, a mask able to block at least part of the light coming from the light source, the light source and the mask being arranged such that, when the transparent cylinder is positioned in the system for inspection, the light source, the mask and the transparent cylinder are substantially aligned along an inspection axis perpendicular to the longitudinal axis of said transparent cylinder and the mask is interposed between the light source and the transparent cylinder so as to prevent illumination of a first portion of the transparent cylinder having a width smaller than the diameter of the transparent cylinder while allowing illumination of a second portion of the transparent cylinder, the mask being configured to provide a contrast with a particle present in the first portion of the transparent cylinder and illuminated by light refracted by the second portion of the transparent cylinder.

METHODS AND APPARATUS FOR CLASSIFYING AN ARTIFACT IN A SPECIMEN

A model-based method of inspecting a specimen for presence of one or more artifacts (e.g., a clot, bubble, and/or foam). The method includes capturing multiple images of the specimen at multiple different exposures and at multiple spectra having different nominal wavelengths, selection of optimally-exposed pixels from the captured images to generate optimally-exposed image data for each spectra, computing statistics of the optimally-exposed pixels to generate statistical data, identifying a serum or plasma portion of the specimen, and classifying, based on the statistical data, whether an artifact is present or absent within the serum or plasma portion. Testing apparatus and quality check modules adapted to carry out the method are described, as are other aspects.

Test container for testing inspection devices
10161880 · 2018-12-25 · ·

A test container for checking container inspection machines, which inspection machines are suitable for examining at least a first category of containers for the presence of foreign bodies, with a main body in which a liquid is disposed, with a mouth via which the liquid is able to be introduced into the container, with a first closure by which the container is closed, wherein a foreign body which can be detected by the inspection machine is disposed in the container is provided. The container and/or the liquid disposed therein has a further substance or for example a transmitting device which can be detected by a user and/or by a detection device in order thus to distinguish the test container per se from another container of the category to be inspected.

Apparatus and method for inspecting filled containers and their filling product
20240280505 · 2024-08-22 ·

An installation for producing containers filled with a liquid, and in particular beverage containers, has at least one transport device which transports containers along a predetermined transport path, a filling device which fills the containers, a closure device which closes the filled containers, and an inspection device that inspects the filled and closed containers, wherein the inspection device is arranged downstream of the closure device along the transport path. The inspection device is configured to output at least one measured value that is characteristic of a composition of the filling product filled into the containers.

METHOD AND APPARATUS FOR INSPECTING FULL CONTAINERS
20240280504 · 2024-08-22 · ·

A method for inspecting filled containers for foreign bodies, comprising: providing a planar illuminating device designed to emit radiation which radiates through a container to be examined; providing a detection device designed to detect the radiation which was emitted by the illuminating device and has radiated through the container and to create a photograph of the container on the basis of the detected radiation; providing an evaluation device designed to evaluate the image created by the detection device; wherein the detection device is aimed, at an acute angle ? relative to the horizontal, at the bottom region of the container to be inspected, and wherein a foreign body on the container bottom is recognized as a local disturbance in the imaging photograph.