Patent classifications
G01N2030/146
DIALYSIS CELL FOR SAMPLE PREPARATION FOR A CHEMICAL ANALYSIS METHOD
The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane.
DIALYSIS CELL FOR SAMPLE PREPARATION FOR A CHEMICAL ANALYSIS METHOD
The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane.
DEVICE AND METHOD FOR INTERFACING TWO SEPARATION TECHNIQUES
The present invention relates to an evaporative membrane concentration device adapted to interface two liquid flow processes, such as two low or high resolution separation techniques or a low or high resolution separation technique and a liquid flow detection technique. For example, the two liquid flow processes may be a liquid chromatography technique and a liquid flow detection technique or a multi-dimensional separation technique, for example, two dimensional liquid chromatography (LCLC) or solvent extraction, such as liquid-liquid extraction or solid phase extraction, with a liquid chromatography technique (LLE or SPE-LC). Methods of using the device and separation and/or chromatographic methods using the device are also described.
SOLVENT RESERVOIR FILTERS, SYSTEMS AND METHODS
A solvent reservoir filter for a liquid chromatograph system includes a first screen extending in a first plane, the first screen configured to filter solvent received through the first screen, a second screen extending in a second plane that is parallel to the first plane, the second screen configured to filter solvent received through the second screen, a main body extending between and connecting the first screen and the second screen, and a fluid outlet configured to expel solvent filtered by the first and second screens from the solvent reservoir filter. Methods of use and assembly of the solvent reservoir filter for a liquid chromatograph system are further disclosed.
Sample collecting and introducing device and detection system
The present disclosure relates to the technical field of safety detection, and in particular to a sample collecting and introducing device and a detection system. The sample collecting and introducing device provided by the present disclosure includes a sampling device for collecting a sample, and a semipermeable membrane device for extracting the sample collected by the sampling device and conveying the extracted sample to detection equipment, wherein the sampling device is provided with an air guide cavity, the air guide cavity is configured to guide airflow carrying the sample to flow to the semipermeable membrane device, the semipermeable membrane device is provided with a semipermeable membrane which is arranged outside the sampling device. In the present disclosure, the size of the semipermeable membrane is no longer limited by the sampling device, and therefore the difficulty of increasing the area of the semipermeable membrane is reduced.
METHOD FOR INITIATING A GRAPHENE OXIDE THROUGH REDUCTION BY A REDUCTANT TO CONTROLLABLY RELEASE ORGANIC COMPOUNDS
The present invention discloses a method for initiating a graphene oxide (GO) through reduction by a reductant to controllably release organic compounds, comprising the following steps: (1) mixing GO and a buffer solution; (2) further mixing with a sewage containing organic contaminants; (3) conducting solid-liquid separation, mixing the solid phase and the pure, introducing and N.sub.2; (4) further adding the reductant; (5) conducting sequential batch kinetics experiment. The present invention utilizes the size effect and polarity control of GO to selectively adsorb aromatic organic contaminants in sewage and fully transfer the selectively adsorbed organic contaminants from a large amount of sewage to a small amount of pure water by initiating using the reductant, and no extraction of the organic phase is required, the time for purification is reduced, and the energy consumption for purification is also reduced.
ADAPTIVE PERFUSION SYSTEMS AND METHODS FOR DRUG RELEASE TESTING
An in vitro release test (IVRT) method and system is provided for drug release testing. The IVRT method, referred to herein as adaptive perfusion, employ tangential-flow filtration (TFF), where released drug products that are smaller than a molecular weight cutoff (MWCO) of a membrane filter pass therethrough into the permeate. Unreleased drug products are retained by the pores of the filter and are recirculated to a retentate reservoir. Fresh media is provided to the retentate in order to maintain a constant total volume for the sample as well as to maintain sink conditions for the drug release. Drug concentration in the retentate and permeate are evaluated by in situ monitoring with one or more sensors and/or by periodic removal of aliquots from the respective reservoirs. In some embodiments, the membrane filter can be conditioned prior to use in order to improve the accuracy, precision, or both of the subsequent testing.
METHOD FOR REMOVING FXI WHEN PURIFYING PLASMA PROTEINS
Disclosed is a method for removing factor XI (FXI) during plasma protein purification, more specifically a method for removing FXI including dialyzing and concentrating a plasma protein fraction II paste containing FXI and a plasma protein, and then removing the FXI using a ceramic-based cation exchange resin. The method for removing factor XI (FXI) can improve removal efficiency of impurities and thrombogenic substances, thereby producing stable plasma proteins with improved quality.
METHOD, SYSTEM, AND APPARATUS FOR GAS CHROMATOGRAPHY DEVICE WITH PRE-CHARGED LARGE VOLUME TO SMALL VOLUME INJECTION MODULE
The present invention contemplates a variety of improved techniques including an injection module pairable with an injection port of a gas chromatography device. The injection module can include a cylindrical body, a cap with permeable membrane, a first reservoir for a sample, and a second reservoir for a volume of solvent. An internal membrane can be disposed between the first reservoir and the second reservoir. The injection module can include a circular plunger creating a seal with an inner surface of the cylindrical body of the injection module and configured to expel the sample and solvent by gliding along the inner surface of the cylindrical body. A server can monitor analytes detected by the gas chromatography device and generate recommendations for a user of the gas chromatography device.
SAMPLE COLLECTING AND INTRODUCING DEVICE AND DETECTION SYSTEM
The present disclosure relates to the technical field of safety detection, and in particular to a sample collecting and introducing device and a detection system. The sample collecting and introducing device provided by the present disclosure includes a sampling device for collecting a sample, and a semipermeable membrane device for extracting the sample collected by the sampling device and conveying the extracted sample to detection equipment, wherein the sampling device is provided with an air guide cavity, the air guide cavity is configured to guide airflow carrying the sample to flow to the semipermeable membrane device, the semipermeable membrane device is provided with a semipermeable membrane which is arranged outside the sampling device. In the present disclosure, the size of the semipermeable membrane is no longer limited by the sampling device, and therefore the difficulty of increasing the area of the semipermeable membrane is reduced.