A method for the production and filling of an application package for a liquid pharmaceutical product. A thermoforming film of thermoplastics laminated together is heated in order to plasticize the film at least in partial areas. Plasticized areas are thermoformed in a mold in order to form a chamber for the liquid pharmaceutical product and a tube-shaped application duct opening into this chamber, with the chamber and duct being enclosed by a non-thermoformed, essentially flat bonding area of the film. The liquid pharmaceutical product is filled into the chamber. The chamber and the application duct are sealed by covering the thermoformed and filled thermoforming film with an essentially flat covering film that is bonded to the bonding area of the thermoforming film enclosing the chamber and the application duct. The thermoforming film is pressed by a forming die during thermoforming into the mold in at least a partial area of the application duct.

A package for delivering a single-dose product includes a softgel capsule which is comprised of at least one gelling agent selected from protein-based gelling agents and polysaccharide-based gelling agents. The capsule shell includes one or more areas of reduced thickness that are preferentially ruptured by exertion of a compressive force on the softgel capsule to create an opening in the capsule shell through which the fill composition can be delivered by spraying or squeezing. A method for manufacturing the softgel capsule having one or more areas of reduced shell thickness is also described.

The invention relates to a liquid applicator, for administering liquids, including vaccines, to animals. In particular, the applicator is useful for delivering liquids to mouths of animals.

A dispenser actuator assembly (100) actuates a dispenser (10). The dispenser (10) is a plastic ampoule (10) having a container (48) having an outer wall (50) and membrane (52) collectively defining a first chamber (54) containing a flowable material (M). The membrane (52) has a weld seam (56). The actuator assembly (100) has a base member (102) configured to mount on the container (48). A fracturing mechanism (116) is operably connected to the base member (102). The fracturing mechanism (116) has a first extending member (132a) and a second extending member (132b), the first extending member (132a) and the second extending member (132b) positioned on the base member (102) in opposed relation. Each extending member (132a,132b) has a projection (150a,150b) positioned proximate the membrane (52). In response to deflection of the extending members (132a,132b) towards one another, the projections (150a,150b) are configured to deflect the outer wall (50) proximate the membrane (52) wherein the weld seam (56) fractures to create an opening through the membrane (56) to allow the flowable material (M) to pass therethrough.

A container, in particular in ampoule form, and consisting entirely or predominantly of plastic materials, having a container body (10) for receiving a filling product (12), which can be removed via a releasable container opening (22) after a closure part (18) has been removed, which is detachably connected to the neck part (14) of the container body (10) along a separation line (20) in an unopened position, is characterized in that, in the unopened position, a conically extending wall (36) on the neck part (14) on the container body (10) and a conically (38) or cylindrically extending wall (38a) on the closure part (18) adjoin the separation line (20), and that these walls (36, 38, 38a) delimit at least part of an annular space (40, 40a), one end of which opens out into the environment and the other end of which opens out into the separation line (20).

The invention relates to a method for the manufacture of at least one flexible plastic container, according to which method each container (10) comprises two separate walls (12, 13) facing one another joined at their circumference by a sealed peripheral edge (14), said separate walls defining a storage space of the container (10). According to the invention, at least the following stages are realized: a) Forming a pile of two sheets (26, 27) of plastic material, said sheets (26, 27) being laid one against the other, the surfaces which face one another of these sheets (26, 27) being placed directly in contact with one another without any element acting as an interface, b) Simultaneously shaping said sheets (26, 27) thus laid one against the other in order to define said at least one container (10) without having previously separated these sheets, at least each container (10) being partially formed, said sheets (26, 27) being maintained lying one against the other in at least one section of the areas of said sheets (26, 27) intended to constitute said peripheral edge (14) of each container (10) during this shaping and c) Sealing at least partially the areas of said sheets (26, 27) intended to constitute said peripheral edge (14) of at least each container (10).

A medicine dispensing device includes a first tubular body and a second tubular body. The first tubular body has an internal receiving space for disposing a liquid medicine and a stop member. A removable section is disposed at a dispensing end of the first tubular body. A neck section is disposed at one end distal from the removable section. The second tubular body includes a tube sealing section, a compression section and a communication tube section. One end of the communication tube section, which end is distal from the tube sealing section, is in communication with the neck section, whereby the receiving space is in communication with the interior of the second tubular body. The stop member blocks the neck section and interrupts the internal passage of the neck section to prevent the liquid medicine from flowing into or stagnating in the second tubular body in use.

A disposable container for containing a patient-customized medicinal fluid as a flowable material, which is adapted to dispense and seal the flowable material, the disposable container including: a plurality of container portions adapted to form spaces containing the flowable material; a bonding portion extended from tops of the container portions in such a manner as to come into contact with a surface of a film protecting the flowable material from the outside; and discharge portions extended from undersides of the container portions in such a manner as to be separable from the containing portions to discharge the flowable material to the outside, wherein the bonding portion connects the container portions with each other.

A container, in particular an ampule, of a plastic material has a container part (10) for receiving the contents of a container (14) to be dispensed via a container opening (12). Opening (12) is closed by a head part (18) that can be separated along a separation line (16). The head part (18) is adjoined by a neck part (20), which has a plurality of different functional surfaces on the inner circumference. One functional contact surface (44) is used to seal against a withdrawal body (32), which is provided for withdrawing the contents of a container (14) when the container opening (12) is opened. A lead-in area (50) is provided as a further functional surface on the interior of the neck part (40) and differs geometrically from the functional contact surface (44). The lead-in area (50) seamlessly merges into the functional contact surface (44). The lead-in area (50) and the functional contact surface are located between the other functional surfaces in the neck part (20).

The present invention relates to a container, which accommodates a drug and is sealed, includes a container stopper part including at least one filling groove formed in order to inject a drug, and a container body including an opening into which the container stopper part is inserted and which is sealed, wherein the filling groove is formed in an outer wall surface of the container stopper part in a longitudinal direction in which the container stopper part is inserted thereinto and forms a passage which is formed between the outer wall surface of the container stopper part and an inner wall surface of the container body and through which the drug is injectable.