A needle-less vial assembly that includes a substance transfer assembly configured to telescopically engage with a vial neck of a vial. A first portion of the substance transfer assembly is configured to sealingly engage with an interior wall of the vial neck, where the first portion includes a first inlet configured to receive a substance from the vial. A second portion of the substance transfer assembly is configured to matingly engage with a syringe, and includes an outlet configured to dispense the substance to the syringe. A channel is defined through the first portion and the second portion, thereby enabling fluid communication of the substance from the vial to the syringe via the first inlet and the outlet.

Methods for compounding a therapeutic agent for intravenous administration. The method comprise providing a syringe or vial comprising the agent dissolved or pre-dissolved in a carrier at a dose or concentration that is therapeutically effective for a particular patient but is not commercially available at the therapeutically effective dose or concentration or is on the U.S. FDA drug shortage list, and adding the therapeutic agent dissolved in the carrier to an intravenous solution (diluent). The methods exclude reconstituting multiple solid forms of the commercially available agent and combining the reconstituted preparations together, for example, according to traditional compounding procedures at point-of-care pharmacies.

The present invention provides a deflectable guide whose use results in protection of the hand of medical personnel holding a medical container during the activity of moving a hypodermic needle toward and pressing it through a septum of the medical container. The present invention further is adapted for use of the same syringe and deflector guide protected needle for injection or withdrawal of medical liquids from a septum end of medical catheter or intravenous tubing without removal of the deflectable guide.

This CIP, Continuation-in-part, presents constructive details of the material contained in the original document BR 10 2016 016091-0 and not specified until then, and the valve (3) can also be used in transfers, dilution and drip chamber and medicine bottles, vaccines and related, the valve (3) has five basic components: conical base (4), which receives in its interior the assembly of the second component, which is the conical movable part (7); the conical base (4) which receives in its core (16) the assembly of the third component which is a smaller diameter o-ring sealing ring (13); on the other hand, the conical movable part (7) receives in its lower groove (14) the assembly of the fourth component, which is a larger diameter o-ring sealing ring (12); the conical base (4) receives the assembly of the fifth component which is the cap (10), which protects the thread in the luer-lock pattern (8); the cover (10) prevents the separation of the conical movable part (7) in relation to the conical base (4); the movable conical part (7) has a surface (22) with an angulation (X), equal to that verified on the inner surface (27) of the conical base (4); the constructive variation of the valve (3a) is fixed to the mouthpiece (6a) of the bottle (F) through its conical base (4), this adjusted to the diameter of the bottle, keeping the valve system unchanged; in addition, the cover (10) of the valve (3a) presents a constructive variation (not shown) formed by a cylindrical body, internally threaded, provided with a lower ring connected to the cover body through a plurality of breaking points, welding points plastic or shrink.

An apparatus comprises a body having an opening at a first end of the body. A plunger control grip is slidably coupled to a portion of the body circumference and configured to couple to a syringe plunger. The apparatus further comprises a cover pivotably coupled to the first end of the body, wherein in an open position the cover exposes a cavity configured to receive a syringe. A locking mechanism is pivotally secured to the cover, wherein the locking mechanism is configured to prevent forward movement of the plunger control grip when in a locked position and to enable forward movement of the plunger control grip when in an unlocked position. The unlocked position is activated by external contact with the locking mechanism and forward movement is in the direction toward the first end of the body.

A device for transferring a toxic substance from a dispensing vessel to at least one receiving vessel comprising: (i) a receiving portion arranged to receive a dispensing vessel containing a toxic substance; and (ii) a transfer apparatus having a first infusion line adapted for fluid communication with the dispensing vessel to transfer a carrier fluid into said vessel and a second infusion line having one end adapted for fluid communication to withdraw and transfer the carrier fluid and the toxic substance from the dispensing vessel and the other end of the second infusion line arranged to connect with the at least one receiving vessel.

The invention relates to an adapter (1) for a transfer device (20) for a fluid, for the connection of a container (17) containing the fluid, wherein the container (17) is closed by a pierceable closure element (18), and the adapter (1) has an attachment (4) which can be fitted sealingly, in an attachment direction, onto a container mouth closed by the closure element. A penetration element (6) is mounted on the attachment (4) in such a way that the penetration element (6) is movable, with the aid of guide means, between a rest position (R) and a withdrawal position (E), wherein the penetration element (6) has a hollow needle (9) with which the closure element (18) can be pierced in the withdrawal position (E). The adapter (1) has a connector stub (3) with a coupling for the fluid-tight connection of a further adapter (1′), and a transfer channel (10) runs from a mouth on the connector stub (3) to a mouth on the hollow needle (9), such that the mouth of the transfer channel (10) on the connector stub (3) communicates with an interior of the connected container (17) in the withdrawal position (E) of the penetration element (6). The invention is characterized in that the connector stub (3) is arranged transversely, in particular substantially perpendicularly, with respect to the attachment direction (H), preferably on the penetration element (6).

A carousel configured to house a plurality of pump cartridges for a compounder system is provided. The carousel may include a plurality of cartridge pockets each having an extended portion that covers a portion of a cartridge and a bottom surface Shaving an extension with a recess. The bottom surface recess of each cartridge pocket may be shaped and sized to receive a needle housing of a pump cartridge in the cartridge pocket. A recess may be provided in the extended portion of each pocket that receives a protrusion that extends from a top surface of a backpack coupled to the pump cartridge to secure the pump cartridge in the cartridge pocket. The bottom surface recess may have an additional bottom surface that prevents actuation of the needle housing of the pump cartridge.

A sampling device including a body (101) having a sampling chamber (102) adapted to receive a liquid (103) to be sampled. An inlet (104) on the body (101) allows liquid (103) to flow into the sampling chamber (102). A sampling port (105) on the body is adapted to receive a sampling pot or sample receiving container (106) for collecting liquid (103) from the sampling chamber (102) wherein the sampling port includes a safety shield (107) slidaby mounted to the inside (108) of the sampling port, the safety shield slidable between a blocking position in which access to the sampling chamber is restricted and an accessible position in which access to the sampling chamber is allowed.

In a connection device, when a cannula holding member is in a use state, a position of an end portion of an outer cylindrical portion on a retracted position side does not protrude to the retracted position side, with respect to a position of an end portion of an inner cylindrical portion on the retracted position side. Thereby, a connection device including a structure capable of holding a vial by holding means irrespective of the size of the vial can be provided.