A mass measuring apparatus includes a transferring and gripping device for removing an article from a seat of a movement device, holding the article in a measuring position, and then reinserting the article into the seat. The transferring and gripping device includes a gripping element for holding the article, an actuator for operating with an actuating signal on the gripping element to make the gripping element vibrate at a specific resonance frequency, a sensor for measuring a vibration response signal of the gripping element vibrating and supporting the article in the measuring position, a processing unit for receiving the vibration response signal and controlling the actuator to generate an actuating signal to make the gripping element vibrate at an operating resonance frequency, and then calculating a mass of the article by comparing the operating resonance frequency with the resonance frequency of the gripping element.

A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.

A method for tracking product in an installation in which powdered product is processed into manufactured items is provided. The method comprises introducing the powdered product into the installation through at least one inlet, obtaining measurement data for the powdered product from at least one mass sensor positioned in the at least one inlet, and dividing the measurement data into mass units of equal size. The progression of the mass units is then tracked through the installation using measurement data from at least one other mass sensor in the installation.

A capsule socket of a filling machine for two-piece capsules and a socket system having such a capsule socket and a capsule half of a two-piece capsule are disclosed herein. The two-piece capsules have two capsule halves, each with a capsule base and a capsule wall. The capsule socket includes a main body having a receiving space for the capsule half formed therein. The receiving space has a base portion, assigned to the respective capsule base, and a circumferential wall portion for centering the capsule wall. The receiving space has a clamping portion between the base portion and the circumferential wall portion. The clamping portion has a smaller free cross section than the circumferential wall portion. In the transition region from its base to its wall, the capsule half has a capsule part diameter. The clamping portion has a free clamping diameter, which is smaller than the capsule part diameter.

A comestible gelatin capsule 10 for holding a substance in hermetic isolation includes a capsule body 12, a diaphragm 14 located within the capsule body and an end cap 16. Overlapping open end regions of walls 22 and 28 of the capsule body 12 and of the diaphragm 14, respectively, are fused to one another in a fusion welding process wherein the end regions undergo partial phase change so as to form a circumferential fused homogeneous sealing zone 36. The overlapping end regions are bent inwardly in the fusion welding process such that a portion of the wall 22 extends inwardly across a portion of the wall 28 thereby restricting axial movement of the capsule body and the diaphragm relative to one another forming a stable robust and effective hermetic seal.

A feeding and blending apparatus for a system for continuous processing of powder products comprises at least two system inlets for powder products; and at least two feeding and dosing devices arranged in a row. Each of the at least two feeding and dosing devices comprises, an inlet being connected with a system inlet, at least one feeder, at least one actuator configured to operate the at least one feeder, and an outlet being connected with an inlet of the powder blending device. A separation wall is configured to separate a process area from a technical. Process components of the at least two feeding and dosing devices are positioned in the process area and technical components of the feeding and dosing devices are positioned in the technical area. Connections between the at least one actuator and the at least one feeder pass through the separation wall.

A system for polishing capsules includes a brush located at least partially inside a wall arranged around an axis (Z). The brush has bristles arranged around the axis (Z) to form a helical conveying ramp for the capsules. The lengths of the bristles of the brush are distinct and a protrusion is mechanically coupled to the wall to bend at least some of the bristles of the brush when the latter is in rotational movement around the axis (Z).

The present invention relates to a pharmaceutical dosage form for application to a mucous membrane, in particular to a buccal, intestinal, rectal or vaginal mucous membrane, comprising at least one string-like or strip-like preparation comprising the active pharmaceutical ingredient, the dosage from being configured to be wettable during a step of administration to a patient. The invention also relates to a method of producing the pharmaceutical dosage form.

A multi phase soft gelatin dosage form comprising at least one preformed solid dosage form and at least one liquid fill phase. The multi phase soft gelatin dosage forms of the present invention are especially useful to combine at least one solid dosage form and at least one liquid phase for single ingestion. Method and apparatus for manufacturing the multi phase soft gelatin dosage forms are also described. The solid phase, liquid phase or coatings may comprise active pharmaceutical ingredients, nutraceuticals, nutritional supplements, therapeutic substances, functional excipients or combinations thereof.

A system including a containment assembly for enclosing a medication container may comprise a first housing portion or interface portion having a proximal end and a distal end. The interface portion may include a housing wall which defines a channel spanning from the proximal end to the distal end. The channel may be open at the proximal and distal end. The containment assembly may further comprise only two pierceable septa configured to form a barrier to the channel. The containment assembly may further comprise a variable-volume housing portion having a variable volume chamber. The variable-volume portion chamber of the variable-volume housing portion may be in fluid communication with the distal end of the channel.