The present invention relates to non-toxic consumable compositions and formulations comprising chelator and base having synergistic effects on microbial metabolism and/or growth and/or pathogenic effectors and their use to promote and maintain health in mammals. The current invention also relates to non-toxic consumable compositions comprising more than one chelator and/or more than one base. The present invention further relates to methods for selecting said chelator and base composition and methods for detecting conditions in which selected compositions may be used. The present invention relates to the synergistic compositions and methods of their use for maintaining health, promoting health and treating diseases.

The present invention relates to non-toxic consumable compositions and formulations comprising chelator and base having synergistic effects on microbial metabolism and/or growth and/or pathogenic effectors and their use to promote and maintain health in mammals. The current invention also relates to non-toxic consumable compositions comprising more than one chelator and/or more than one base. The present invention further relates to methods for selecting said chelator and base composition and methods for detecting conditions in which selected compositions may be used. The present invention relates to the synergistic compositions and methods of their use for maintaining health, promoting health and treating diseases.

The inventive subject is directed towards ready-to-use topical cosmetic formulations that include at least one defensin present in sub-antimicrobially effective concentrations. Surprisingly, even at such low concentrations, defensins recruit LGR6+ stem cells from hair follicles to the interfollicular space. Including defensins in the inventive topical cosmetic formulations may reduce one or more of wrinkle depth, wrinkle length, wrinkle width, pore size, irregularity in texture of a skin surface, oiliness, brown spots, and red spots in non-injured skin, thus reducing apparent age.

Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

The embodiments relate to improved skin quality, health and appearance using a new delivery method and certain bioactive compositions and formulations. The system incorporates microneedle delivery technology with unique compositions and formulations. Such development allows for the pursuit of personalized medicine, or treatment delivery that can expand to remote controlled environment, immediate compounding and ultimate personalization with a state of the art longitudinal data predictive analytics. Certain formulations described herein are unique, combinatory and synergistic. Secured by high-tech proprietary system, there are unlimited potentials using AQT technology including but not limited to 3-D printing of a biodegradable micro chips that can be delivered via injection, AQT or any other possible route.

One aspect of the invention provides an oil-in-water emulsified cosmetic, which comprises in a cosmetically acceptable medium: a) a hydrogenated lecithin, b) an anionic surfactant derived from microorganisms, c) a polyol comprising a glycerin, d) a polysaccharide, wherein the content of the anionic surfactant preferably ranges from 0.005% to 1% by weight of the total weight of the oil-in-water emulsified cosmetic.

Provided are a cleaner base containing a solid composition including a solid surfactant and a water-soluble polymer, a gel cleaning composition having a viscosity of greater than or equal to about 50 cPs including the cleaner base containing a solid composition and water, and a method for preparing the gel cleaning composition.

A topical sunscreen composition including a lotion having titanium dioxide, zinc oxide, water, avocado oil, sunflower oil, bee's wax, coconut oil, monolaurin, stearyl dimethicone, cetylesters, ethyl linoleate, triethyl citrate, fragrance and Lecithin. In another aspect, there is disclosed a topical sunscreen composition including a lotion having zinc oxide, water, avocado oil, zeolite, bee's wax, coconut oil, monolaurin, ethyl linoleate, bentonite, tri ethyl citrate, fragrance and Lecithin.

The present application relates to a composition comprising, notably in a physiologically acceptable medium: a. water; and b. at least one cellulosic cationic polymer (CP); and c. at least one anionic polymer (AP) chosen from methacrylic acid homopolymer salts; and d. at least one anionic surfactant comprising at least one cationic counterion; and e. a fatty phase; and f. at least one pigment; the weight ratio of the total amount of cellulosic cationic polymer(s)/the sum of the total amount of cellulosic cationic polymer(s) and of the total amount of anionic polymer(s) ranging from 40% to 80%, preferably from 60% to 70%; the weight ratio of the sum of the total amount of cellulosic cationic polymer(s) and of the total amount of anionic polymer(s)/the amount of water ranging from 5% to 20%. The invention also relates to a process for coating keratin materials, in particular the skin, notably the contour of the eyes, eyelashes or eyebrows, and keratin fibers, such as the eyelashes and/or the eyebrows, comprising a step of applying to said keratin materials at least one composition as defined above.

The present application relates to a composition comprising, notably in a physiologically acceptable medium: a. water; and b. at least one cellulosic cationic polymer (CP); and c. at least one anionic polymer (AP) chosen from methacrylic acid homopolymer salts; and d. at least one anionic surfactant comprising at least one cationic counterion; and e. a fatty phase; and f. at least one pigment; the weight ratio of the total amount of cellulosic cationic polymer(s)/the sum of the total amount of cellulosic cationic polymer(s) and of the total amount of anionic polymer(s) ranging from 40% to 80%, preferably from 60% to 70%; the weight ratio of the sum of the total amount of cellulosic cationic polymer(s) and of the total amount of anionic polymer(s)/the amount of water ranging from 5% to 20%. The invention also relates to a process for coating keratin materials, in particular the skin, notably the contour of the eyes, eyelashes or eyebrows, and keratin fibers, such as the eyelashes and/or the eyebrows, comprising a step of applying to said keratin materials at least one composition as defined above.