First and second filter magazines in each of which plural filters having different transmission wavelengths from each other are arranged in a row are provided, and the first and second filter magazines are arranged next to each other in one direction. A light detection unit in which plural photomultipliers of first and second photomultipliers, each of which detects light that has passed through at least one of the filters included in the first and second filter magazines, are arranged in the arrangement direction of the filters is provided, and the light detection unit is placed in the one direction in such a manner to be parallel to the first and second filter magazines. The apparatus is configured in such a manner that the first and second filter magazines and the light detection unit are movable in the arrangement direction of the filters.

A banknote discrimination apparatus includes a plurality of photoelectric conversion elements in which an incident light including fluorescence emitted from a banknote irradiated with excitation light enters; a plurality of organic film filters that are arranged so as to overlap each of the plurality of photoelectric conversion elements, and have mutually different transmission bands; a circuit including a plurality of pixel circuits which are each connected to one corresponding element among the plurality of photoelectric conversion elements and output a pixel signal converted by each photoelectric conversion element in accordance with an intensity of the incident light that transmits through the organic film filter and enters to the photoelectric conversion element; a spectral processor; and a discriminator. At least one of the plurality of organic film filters is a filter obtained by overlapping two or more filter layers on each other.

The present invention relates to an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (35). The present invention also relates to an observation system (3) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter (21) adapted to split a light image (13) into a first light portion (16, 17) along a first light path (18) and a second light portion (20) along a second light path (19). To improve known illumination filter systems and observation systems, so these systems work with one light source only, are capable of capturing simultaneously at least one fluorescence signal and a signal of visible reflected light and allow a homogeneous illumination for obtaining different images from the object illuminated, the first optical filter (36) is adapted to quench light of at least one fluorescence excitation band within the visible spectrum in the illumination filter system (2) of the present invention, and the first light portion (16, 17) comprises at least one fluorescence emission band (Em.1, Em.2) in the visible spectrum and the second light portion (20) portion comprises a visible reflected light (VISR) in the observation system (3) of the present invention.

The invention relates to an illumination filter (36, 44) for an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope. The present invention provides an illumination filter for medical imaging, in particular a multispectral fluorescence imaging, that is capable of capturing simultaneously more than one fluorescence signal, and allow a homogeneous illumination for obtaining different images from the object illuminated by comprising a spatial filter pattern (43) masking a defined filtering fraction of a first illumination path (47) on the filter and masking a defined filtering fraction of a second illumination path (48, 49, 50) on the filter, wherein the filtering fraction of the first and the second illumination paths (47, 48, 49, 50) are different. The invention further relates to an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope, comprising such illumination filter (36, 44).

A sample observation device includes an irradiation unit that irradiates a sample with planar light, a scanning unit that scans the sample in one direction with respect to an irradiation surface of the planar light, an image formation unit that forms images of fluorescent light and scattered light from the sample, an imaging unit that outputs first image data based on a light image of the fluorescent light and second image data based on a light image of the scattered light, an image processing unit that generates a fluorescent light image on the basis of a plurality of pieces of first image data and generates a scattered light image on the basis of a plurality of pieces of second image data, and an analysis unit that specifies an area in which there is the sample in the fluorescent light image on the basis of the scattered light image, and sets an analysis area in the fluorescent light image on the basis of the area in which there is the sample.

A microplate reader includes a pair of linear variable filters (LVFs) that together form a wavelength selector. Movement of one or both of the LVFs enables selection of the desired center wavelength and/or passband used to analyze a sample on a microplate inserted into the microplate reader. The microplate reader may also include a similar second wavelength selector. The LVFs are located on movable frames, with each frame also advantageously including least one of an aperture, a fixed optical filter, and an optical polarization filter. In some cases, different types of measurements may be taken without changing the geometry of the optical path between the wavelength selectors. The microplate reader may additionally use a LVF to form a continuously adjustable dichroic for sample analysis.

To avoid unstable light radiation during switching of a phase modulation amount and stimulate desired stimulation points simultaneously, provided is a photo-stimulator which includes an AOM switching on/off of radiation of stimulation light to a specimen S; an LCOS-SLM being capable of modulating a phase of stimulation light once radiation to the specimen S has been turned on by the AOM; and a controller controlling the LCOS-SLM to switch a phase modulation amount of stimulation light and controlling the AOM to switch on/off of radiation of stimulation light, wherein the controller causes the AOM to turn off radiation of stimulation light before the LCOS-SLM starts switching a phase modulation amount, and causes the AOM to turn on radiation of stimulation light after the LCOS-SLM completes switching a phase modulation amount.

An optical sensing module is configured to detect a characteristic of a sample. The optical sensing module includes a light source, a light guide plate, a first cladding layer, a light converging layer, a filter layer, and a plurality of sensors. The light source is configured to provide an exciting beam. Positions of the sensors correspond to positions of the holes. After the exciting beam enters the light guide plate, at least one portion of the exciting beam is transmitted to the sample through a portion of the surface of the light guide plate exposed by the holes, the sample is excited by the exciting beam to emit a signal beam, and the signal beam passes through the light converging layer and the filter layer in an order and travels to the sensors. Another optical sensing module is also provided.

Systems and methods here may be used for capturing and analyzing spectrometer data of multiple sample gemstones on a stage, including mapping digital camera image data of samples, for both reflective and transmission modes.

The invention relates to an apparatus for the investigation of surface properties with a housing, a light source which directs light through an opening in the housing onto a surface to be investigated, with a first detector device which is arranged inside at a first pre-set angle with respect to the light beam radiated onto the surface by the light source, with a second detector device which is arranged at a second pre-set angle with respect to the light beam radiated onto the surface by the light source and with a third detector device which is arranged inside the housing at a third pre-set angle with respect to the light beam radiated onto the surface by the light source. According to the invention the apparatus has at least two filter elements with optical properties which are different from each other which are arranged on a common carrier movable with respect to the light source, in such a way that each of these filter elements is optionally capable of being brought into a beam path between the light source and the surface.