A61K35/52

System and method for following and conducting laboratory procedures
10993793 · 2021-05-04 ·

There is provided a system and method for following and conducting laboratory procedures for preventing errors and fatigue of the user. The system involves input means, such as a microscope, and a camera connected to the input means, while the camera creates images of the input means. A computer is connected to the camera, and it processes the images so that augmented reality glasses which are also connected to the computer, are capable of having those images projected thereon. The computer also has laboratory protocol files installed thereon, and it projects images of the protocols onto the glasses. The projected images do not interfere with a user's natural vision.

PHARMACEUTICAL COMPOSITION COMPRISING ISOLATED MITOCHONDRIA FOR PREVENTION OR TREATMENT OF RHEUMATOID ARTHRITIS
20210052659 · 2021-02-25 ·

The present invention relates to a pharmaceutical composition for prevention or treatment of rheumatoid arthritis and, more particularly, to a pharmaceutical composition comprising mitochondria as an effective ingredient for prevention or treatment of rheumatoid arthritis. When a foreign mitochondria pharmaceutical composition of the present invention is administered to a subject suffering from rheumatoid arthritis, the subject may alleviate edema and rubefaction symptoms. In addition, the pharmaceutical composition of the present invention reduces an expression level of the inflammatory cytokine IL-6, but increases an expression level of the anti-inflammatory cytokine IL-10 in the subject. Therefore, the pharmaceutical composition according to the present invention can be effectively used for preventing or treating rheumatoid arthritis.

PHARMACEUTICAL COMPOSITION COMPRISING ISOLATED MITOCHONDRIA FOR PREVENTION OR TREATMENT OF RHEUMATOID ARTHRITIS
20210052659 · 2021-02-25 ·

The present invention relates to a pharmaceutical composition for prevention or treatment of rheumatoid arthritis and, more particularly, to a pharmaceutical composition comprising mitochondria as an effective ingredient for prevention or treatment of rheumatoid arthritis. When a foreign mitochondria pharmaceutical composition of the present invention is administered to a subject suffering from rheumatoid arthritis, the subject may alleviate edema and rubefaction symptoms. In addition, the pharmaceutical composition of the present invention reduces an expression level of the inflammatory cytokine IL-6, but increases an expression level of the anti-inflammatory cytokine IL-10 in the subject. Therefore, the pharmaceutical composition according to the present invention can be effectively used for preventing or treating rheumatoid arthritis.

COMPOSITION FOR ENDOGENOUS PRODUCTION OF CHECKPOINT PROTEIN PRECURSORS
20200368369 · 2020-11-26 ·

The present disclosure relates to one or more agents, therapies, treatments, and methods of use of the agents and/or therapies and/or treatments for upregulating production and/or functionality of one or more protein precursors of IDO-1, CTLA-4, PD-1, PD-L1, PD-L2 and INF-y. Embodiments of the present disclosure can be used as a therapy or a treatment for a subject that has a condition whereby the subject's immune system is or is likely to become, dysregulated and where the upregulation of these protein precursors may be of therapeutic benefit.

COMPOSITION FOR ENDOGENOUS PRODUCTION OF CHECKPOINT PROTEIN PRECURSORS
20200368369 · 2020-11-26 ·

The present disclosure relates to one or more agents, therapies, treatments, and methods of use of the agents and/or therapies and/or treatments for upregulating production and/or functionality of one or more protein precursors of IDO-1, CTLA-4, PD-1, PD-L1, PD-L2 and INF-y. Embodiments of the present disclosure can be used as a therapy or a treatment for a subject that has a condition whereby the subject's immune system is or is likely to become, dysregulated and where the upregulation of these protein precursors may be of therapeutic benefit.

Compositions and Methods for Ablating Niche Cells in Testis and Other Epithelial Cells and Methods Relating Thereto
20200345667 · 2020-11-05 ·

The present disclosure relates to compositions and methods for ablating epithelial cells, in particular to methods for ablating Sertoli cells in testis, and methods related thereto. In particular, the present disclosure relates to methods for ablating Sertoli and other cells in the testis using benzalkonium chloride, to methods for rescuing endogenous spermatogenesis in a subject suffering from Sertoli cell dysfunction, to methods of reconstructing spermatogenesis, to methods of treating infertility, and to methods for the selective depletion of epithelial cells in a tissue and for the treatment of diseases or disorders associated with damaged epithelial cells.

Compositions and Methods for Ablating Niche Cells in Testis and Other Epithelial Cells and Methods Relating Thereto
20200345667 · 2020-11-05 ·

The present disclosure relates to compositions and methods for ablating epithelial cells, in particular to methods for ablating Sertoli cells in testis, and methods related thereto. In particular, the present disclosure relates to methods for ablating Sertoli and other cells in the testis using benzalkonium chloride, to methods for rescuing endogenous spermatogenesis in a subject suffering from Sertoli cell dysfunction, to methods of reconstructing spermatogenesis, to methods of treating infertility, and to methods for the selective depletion of epithelial cells in a tissue and for the treatment of diseases or disorders associated with damaged epithelial cells.

COMPOSITION COMPRISING CHP (CYCLO-HIS PRO) FOR PREVENTING, IMPROVING OR TREATING OF BONE LOSS RELATED DISEASE

A composition containing cyclo-hispro (CHP) and its use in preventing, alleviating, or treating bone loss diseases are disclosed. The composition contains CHP or a CHP-containing prostate extract.

COMPOSITION COMPRISING CHP (CYCLO-HIS PRO) FOR PREVENTING, IMPROVING OR TREATING OF BONE LOSS RELATED DISEASE

A composition containing cyclo-hispro (CHP) and its use in preventing, alleviating, or treating bone loss diseases are disclosed. The composition contains CHP or a CHP-containing prostate extract.

CHARACTERIZING SPERM AND CORRELATING THEIR DNA
20200306320 · 2020-10-01 ·

Sperm can be separated by nonlethal methods in a sorting track that into cubicles having different cubicle characteristics. A test sample of sperm from selected cubicles can be sacrificed to determine their prevalent genetic characteristics. The visually identifiable characteristics of sperm from the test samples can also be correlated with prevalent genetic characteristics. A living sperm, sharing selected genetic characteristics, can be selected from remaining sperm having similar identifiable characteristics in a respective cubicle and used for fertilizing an egg.