The present invention discloses a herbal composition for prevention and treatment of joint pain, the method of preparation thereof, and its application thereof. The composition relieves osteoarthritis pain and substantially treats osteoarthritis. It can be used for the prevention and treatment of osteoarthritis of various joints, including the knee joint, hip joint, wrist joint, spine joint, shoulder joint, and ankle joint. The composition disclosed herein can be formulated into tablet, capsule, dispersible tablet, chewable tablet, effervescent tablet, and buccal tablet. The composition comprises a mixture of glucosamine sulfate 2KCl, chondroitin sulfate, methyl-sulfonyl-methane (MSM), and any one or a combination of Sambucus williamsii Hance extract and Drynaria fortunei (Kunze) J. Sm. extract. Further, the mixture may comprise any one or a combination of type II collagen, Morinda officinalis root extract, Epimedium grandiflorum extract, and turmeric root extract. Preferably, the mixture is sieved and formulated into a dosage form with 0.10 g to 1.50 g of the mixture per dose. As compared to the prior art, the present invention offers advantages such as simple processing method, explicit functional components, and minimal side effects.

The present invention discloses a herbal composition for prevention and treatment of joint pain, the method of preparation thereof, and its application thereof. The composition relieves osteoarthritis pain and substantially treats osteoarthritis. It can be used for the prevention and treatment of osteoarthritis of various joints, including the knee joint, hip joint, wrist joint, spine joint, shoulder joint, and ankle joint. The composition disclosed herein can be formulated into tablet, capsule, dispersible tablet, chewable tablet, effervescent tablet, and buccal tablet. The composition comprises a mixture of glucosamine sulfate 2KCl, chondroitin sulfate, methyl-sulfonyl-methane (MSM), and any one or a combination of Sambucus williamsii Hance extract and Drynaria fortunei (Kunze) J. Sm. extract. Further, the mixture may comprise any one or a combination of type II collagen, Morinda officinalis root extract, Epimedium grandiflorum extract, and turmeric root extract. Preferably, the mixture is sieved and formulated into a dosage form with 0.10 g to 1.50 g of the mixture per dose. As compared to the prior art, the present invention offers advantages such as simple processing method, explicit functional components, and minimal side effects.

The present invention discloses a herbal composition for prevention and treatment of joint pain, the method of preparation thereof, and its application thereof. The composition relieves osteoarthritis pain and substantially treats osteoarthritis. It can be used for the prevention and treatment of osteoarthritis of various joints, including the knee joint, hip joint, wrist joint, spine joint, shoulder joint, and ankle joint. The composition disclosed herein can be formulated into tablet, capsule, dispersible tablet, chewable tablet, effervescent tablet, and buccal tablet. The composition comprises a mixture of glucosamine sulfate 2KCl, chondroitin sulfate, methyl-sulfonyl-methane (MSM), and any one or a combination of Sambucus williamsii Hance extract and Drynaria fortunei (Kunze) J. Sm. extract. Further, the mixture may comprise any one or a combination of type II collagen, Morinda officinalis root extract, Epimedium grandiflorum extract, and turmeric root extract. Preferably, the mixture is sieved and formulated into a dosage form with 0.10 g to 1.50 g of the mixture per dose. As compared to the prior art, the present invention offers advantages such as simple processing method, explicit functional components, and minimal side effects.

Use of extracellular vesicles of Rhizoma Drynariae in the preparation of a medicine for treating orthopedic diseases. The extracellular vesicles are extracted from the traditional Chinese medicine Rhizoma Drynariae, so that proliferation and differentiation of the bone marrow mesenchymal stem cells can be promoted, and the bone targeting property is achieved; in addition, various functional components which are the same as those of Rhizoma Drynariae are contained, so that the potential of treating orthopedic diseases is proved. Therefore, the extracellular vesicles of Rhizoma Drynariae can be applied to the preparation of a medicine for treating orthopedic diseases.

Use of extracellular vesicles of Rhizoma Drynariae in the preparation of a medicine for treating orthopedic diseases. The extracellular vesicles are extracted from the traditional Chinese medicine Rhizoma Drynariae, so that proliferation and differentiation of the bone marrow mesenchymal stem cells can be promoted, and the bone targeting property is achieved; in addition, various functional components which are the same as those of Rhizoma Drynariae are contained, so that the potential of treating orthopedic diseases is proved. Therefore, the extracellular vesicles of Rhizoma Drynariae can be applied to the preparation of a medicine for treating orthopedic diseases.

Disclosed herein is a method for manufacturing a composition promoting recovery from a bone fracture, the method including preparing a mixture of Angelica gigas, Cnidium officinale, Phlomis umbrosa, Astragalus membranceus, Amomi fructus, Citri unshius pericarpium, Drynariae Rhizoma, Codonopsis Pilosulae Radix, frankincense, and myrrh, aging the mixture, smoking the mixture, drying the mixture and grinding the dried mixture into a powder, and extracting a liquid from the powder.

Disclosed herein is a method for manufacturing a composition promoting recovery from a bone fracture, the method including preparing a mixture of Angelica gigas, Cnidium officinale, Phlomis umbrosa, Astragalus membranceus, Amomi fructus, Citri unshius pericarpium, Drynariae Rhizoma, Codonopsis Pilosulae Radix, frankincense, and myrrh, aging the mixture, smoking the mixture, drying the mixture and grinding the dried mixture into a powder, and extracting a liquid from the powder.