A feed additive for swine consists of following ingredients measured by weight: 20-50 sour jujubes, 10-18 radix bupleuri, 6-20 codonopsis pilosula, 10-20 honeysuckles, 10-20 isatis roots, 10-18 chrysanthemums, 6-9 red jujubes, 10-20 myrica rubra and 30-60 cactuses. The disclosure further provides a feed composition for swine with the above feed additive. The above-mentioned feed additive for swine is effective in preventing hog cholera, convenient in use, no toxicity, side effects or medical residue, which benefits human health.

A herbal composition for relieving sleep disorder, comprising, by percentage weight, active ingredients of 2.5% Hovenia extract, 12.5% rattan extract, 7.5% lemon extract, 7.5% jujube kernels extract, 15% valerian root extract, and 5% panax notoginseng; auxiliary ingredients of 0.05% vitamin B1, 0.50% vitamin B3, 0.05% vitamin B6, 0.01% folic acid (vitamin B9), and 0.10% vitamin B12; and an accessory composition of 36.97% xylitol, 7.39% cellulose, 1.97% stearic acid, 0.99% natural color and flavor, 0.99% silicon dioxide, 0.49% croscarmellose Na, and 0.49% magnesium stearate. The herbal composition has significant anxiolytic effect, well-maintained bioavailability of DHM, no significant toxic or side effect and not causing addictive or withdrawal effect, thereby prolonging sleep duration and quality without causing any significant side effect.

A herbal composition for relieving sleep disorder, comprising, by percentage weight, active ingredients of 2.5% Hovenia extract, 12.5% rattan extract, 7.5% lemon extract, 7.5% jujube kernels extract, 15% valerian root extract, and 5% panax notoginseng; auxiliary ingredients of 0.05% vitamin B1, 0.50% vitamin B3, 0.05% vitamin B6, 0.01% folic acid (vitamin B9), and 0.10% vitamin B12; and an accessory composition of 36.97% xylitol, 7.39% cellulose, 1.97% stearic acid, 0.99% natural color and flavor, 0.99% silicon dioxide, 0.49% croscarmellose Na, and 0.49% magnesium stearate. The herbal composition has significant anxiolytic effect, well-maintained bioavailability of DHM, no significant toxic or side effect and not causing addictive or withdrawal effect, thereby prolonging sleep duration and quality without causing any significant side effect.

The invention relates to a composition containing extracts of the fruit of Hovenia dulcis Thunb., gallocatechin, and methyl vanillate as active ingredients for preventing and treating bone disease. The extracts of the fruit of Hovenia dulcis Thunb., the gallocatechin, and the methyl vanillate according to the present invention are natural materials and thus cause no side effects, and may activate the Wnt/-catenin pathway to promote bone formation rather than inhibiting bone decomposition, and therefore may be effective in treating osteoporosis and related diseases. In addition, the extracts of the fruit of Hovenia dulcis Thunb., the gallocatechin, and the methyl vanillate according to the present invention may have the effects regrowing hair and preventing and treating wounds and metabolic diseases related to the activation of Wnt/-catenin pathway.

The invention relates to a composition containing extracts of the fruit of Hovenia dulcis Thunb., gallocatechin, and methyl vanillate as active ingredients for preventing and treating bone disease. The extracts of the fruit of Hovenia dulcis Thunb., the gallocatechin, and the methyl vanillate according to the present invention are natural materials and thus cause no side effects, and may activate the Wnt/-catenin pathway to promote bone formation rather than inhibiting bone decomposition, and therefore may be effective in treating osteoporosis and related diseases. In addition, the extracts of the fruit of Hovenia dulcis Thunb., the gallocatechin, and the methyl vanillate according to the present invention may have the effects regrowing hair and preventing and treating wounds and metabolic diseases related to the activation of Wnt/-catenin pathway.

The present invention relates to a method for preparing a granule or a pill containing a plant, medicinal herb or traditional oriental medicine decoction extract, having the steps of: (a) injecting a powdered plant, medicinal herb or traditional oriental medicine decoction extract into a fluidized-bed device and spraying purified water or a solution of the same type of extract as the extract powder at the extract powder while fluidizing the same, thereby generating microgranules of the extract powder; and (b) injecting the microgranules generated at step (a) as seeds into the fluidized-bed device and spraying a solution of the extract while fluidizing the same, thereby growing the microgranules to a predetermined size of granule or pill. According to the present invention, it is possible to prepare a granule or a pill containing an extract in a high concentration.

The present invention relates to a method for preparing a granule or a pill containing a plant, medicinal herb or traditional oriental medicine decoction extract, having the steps of: (a) injecting a powdered plant, medicinal herb or traditional oriental medicine decoction extract into a fluidized-bed device and spraying purified water or a solution of the same type of extract as the extract powder at the extract powder while fluidizing the same, thereby generating microgranules of the extract powder; and (b) injecting the microgranules generated at step (a) as seeds into the fluidized-bed device and spraying a solution of the extract while fluidizing the same, thereby growing the microgranules to a predetermined size of granule or pill. According to the present invention, it is possible to prepare a granule or a pill containing an extract in a high concentration.

The present disclosure relates to a pharmaceutical composition for preventing or treating a cranial nerve disease, comprising a fomes fomentarius extract, a fraction thereof, or a compound isolated therefrom as an active ingredient. According to the present disclosure, the fomes fomentarius extract is included as an active ingredient so that there are significant effects of inhibiting the production or expression of inflammatory cytokines and improving the activity of glucose metabolism in the brain to prevent or treat cranial nerve diseases, of lowering side effects on the human body as a natural product, and of being easily prepared and ingested.

The present disclosure relates to a pharmaceutical composition for preventing or treating a cranial nerve disease, comprising a fomes fomentarius extract, a fraction thereof, or a compound isolated therefrom as an active ingredient. According to the present disclosure, the fomes fomentarius extract is included as an active ingredient so that there are significant effects of inhibiting the production or expression of inflammatory cytokines and improving the activity of glucose metabolism in the brain to prevent or treat cranial nerve diseases, of lowering side effects on the human body as a natural product, and of being easily prepared and ingested.

The present disclosure relates to a pharmaceutical composition for preventing or treating a cranial nerve disease, comprising a fomes fomentarius extract, a fraction thereof, or a compound isolated therefrom as an active ingredient. According to the present disclosure, the fomes fomentarius extract is included as an active ingredient so that there are significant effects of inhibiting the production or expression of inflammatory cytokines and improving the activity of glucose metabolism in the brain to prevent or treat cranial nerve diseases, of lowering side effects on the human body as a natural product, and of being easily prepared and ingested.