Methods, systems, products, devices, and/or apparatus generally related to distortion correction of multiple MRI images based on a full body reference image. An example method for distortion correction of multiple MRI images based on a full body reference image may include acquiring at least one reference image of a subject using a magnetic resonance imaging system, storing a correction field map based on the at least one reference image, the correction field map including information regarding a correction field for each of a plurality of portions of the subject, acquiring a plurality of images by the magnetic resonance imaging system, each of the plurality of images corresponding to a respective portion of the subject, and while acquiring each of the plurality of images, applying a correction field specified by the correction field map for the respective portion of the subject.

An electromagnet model or models are created to generate the static and radio frequency magnetic fields of an NMR downhole logging tool. The magnetic field distributions are then used in spin dynamics (SD) simulations to model the impacts of various effects on NMR logging data, effects that cannot be accurately describe by theoretical formulation alone. The accuracy of the electromagnetic model and the SD simulation may be verified against experimental observations or trial logging runs. Simulation of electronic circuit, molecular diffusion, tool motion can all be incorporated in the SD simulation. The NMR data inversion process can be modified according to echoes obtained from SD simulation to obtain more accurate petrophysical parameters.

In the field of obesity related disease, identification of patients with nonalcoholic steatohepatitis (NASH) would be useful to counsel them more intensively on diet and lifestyle changes and propose new pharmacological treatments. As a consequence, the inventors worked on a method for post-processing images of a region of interest of the liver for reconstructing a map of the internal magnetic susceptibility by using a Bayesian regularization approach to inverse the internal magnetic field. Such method can be implemented on computer and provides better results than other known methods for obesity related disease. This method may be applied for predicting that a subject is at risk of suffering from such disease, diagnosing a disease, identifying a therapeutic or a biomarker and screening compounds useful as a medicine.

The invention provides for a medical imaging system (100, 300) comprising: a memory (110) for storing machine executable instructions (120); and a processor (104) for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive (200) a resting group of B1 phase maps (122) of a region (309) of interest of a subject (318); receive (202) an active group of B1 phase maps (124) of the region of interest of the subject, calculate (204) a resting group of conductivity maps (126) for the region of interest using the resting group of B1 phase maps according to an electrical properties tomography algorithm; calculate (206) an active group of conductivity maps (128) for the region of interest using the active group of B1 phase maps according to the electrical properties tomography algorithm, and calculate (208) a conductivity change mapping (130) for the region of interest using the resting group of conductivity maps and the active group of conductivity maps.

A method of analysing the magnitude of Magnetic Resonance Imaging (MRI) data is described. The method comprising: using the magnitude only of the multi-echo MRI data of images from the subject, where images are acquired at arbitrarily timed echoes including at least one echo time where water and fat are not substantially in-phase; fitting the magnitude of said multi-echo MRI data to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular cost function value for each of the plurality of starting conditions, where said cost function values are independent of a field map term for the MRI data; analysing said cost function values to calculate relative signal separation contribution for each species at each voxel of the images.

Methods, devices, systems and apparatus for dynamic imaging based on echo planar imaging (EPI) sequence are provided. In one aspect, a method includes: obtaining first pre-scanned k-space data by performing a pre-scan for a subject based on a first EPI sequence and pre-scanning parameters, obtaining a pre-scanned image and second pre-scanned k-space data according to the first pre-scanned k-space data, performing a dynamic scan for the subject based on a second EPI sequence and dynamic scanning parameters to generate dynamically-scanned k-space data associated with each of a plurality of dynamic periods in the dynamic scan, and for each of the dynamic periods, generating a residual image according to the dynamically-scanned k-space data of the dynamic period and the second pre-scanned k-space data, and adding the pre-scanned image and the residual image to obtain a dynamic image of the dynamic period.

A B.sub.0-mapping method determines the spatial distribution of a static magnetic field in a pre-selected imaging zone comprising computation of the spatial distribution of a static magnetic field from a spatial distribution of spin-phase accruals between magnetic resonance echo signals from the imaging zone and an estimate of the proton density distribution in the imaging zone. The invention provides the field estimate also in cavities and outside tissue. Also the field estimate of the invention suffers less from so-called phase-wraps.

The invention relates to a method of MR imaging of an object. It is an object of the invention to enable MR imaging using the stack-of-stars acquisition scheme with an enhanced control of the contrast of the reconstructed MR image. The method of the invention comprises the steps of: a) generating MR signals by subjecting the object (10) to a number of shots of a multi-echo imaging sequence comprising RF pulses and switched magnetic field gradients, wherein a train of echo signals is generated by each shot; b) acquiring the echo signals according to a stack-of-stars (i.e. a hybrid radial 3D acquisition scheme wherein radial sampling is performed in each slice plane and phase encoding is performed along the slice encoding direction) or stack-of-spirals scheme, wherein the echo signals are acquired as radial or spiral k-space profiles (S1-S12) arranged at different positions along a slice direction in k-space, wherein echo signals from different k-space slices are acquired in each shot of the imaging sequence and wherein the echo signals are acquired from each k-space slice with different relaxation time weightings; and c) reconstructing at least one MR image of a desired contrast from the acquired echo signals using a k-space weighted image contrast (KWIC) filter. Moreover, the invention relates to a MR device (1) and to a computer program for a MR device (1).

A new method is developed for ultrafast, high-resolution magnetic resonance spectroscopic imaging (MRSI) using learned spectral features. The method uses Free Induction Decay (FID) based ultrashort-TE and short-TR acquisition without any solvent suppression pulses to generate the desired spatiospectral encodings. The spectral features for the desired molecules are learned from specifically designed “training” data by taking into account the resonance structure of each compound generated by quantum mechanical simulations. A union-of-subspaces model that incorporates the learned spectral features is used to effectively separate the unsuppressed water/lipid signals, the metabolite signals, and the macromolecule signals. The unsuppressed water spectroscopic signals in the data can be used for various purposes, e.g., removing the need of additional auxiliary scans for calibration, and for generating high quality quantitative tissue susceptiability mapping etc. Simultaneous spatiospectral reconstructions of water, lipids, metabolite and macromolecule can be obtained using a single .sup.1H-MRSI scan.

In a method for generating at least one MR image of an object in an MR system comprising a plurality of signal receiving coils, a sequence of RF pulses are applied in order to generate a plurality of MR signal echoes, the MR signal-echoes are detected with the plurality of signal receiving coils in a 3-dimension-al k-space, and the at least one MR image is reconstructed using the non-homogeneous under sampled 3-dimensional k-space based on a compressed sensing technology. The 3-dimensional k-space may be undersampled with a plurality of spiral trajectories having different radii resulting in a non-homogeneous undersampled 3-dimensional k-space.