A61K2800/413

Nanoemulsion formulation with improved stability and cell penetration

The present invention relates to a nanoemulsion comprising at least one aqueous component and a carrier, wherein the carrier comprises at least one lipophilic component, at least one surfactant and at least one alcohol. The present invention further relates to a composition comprising said nanoemulsion and an active agent. In particular, the composition is present as a gel and the active agent is 5-aminolevulinic acid, a derivative, precursor and/or metabolite thereof. The invention further relates to the preparation of said nanoemulsion and/or composition and to their use for the treatment of dermatological diseases, virus-associated diseases as well as diseases associated with cell proliferation, in particular, tumor diseases and/or psoriasis. The present invention is further directed to the use of said nanoemulsion in cosmetics.

Eye-makeup cosmetic composition

The present invention relates to a colored cosmetic composition for making up eyes, in particular eyelids. One of the aspects of the present invention is a colored cosmetic composition for making up eyes, in particular to eyelids, comprising: (i) at least one polymer which has a Tg of −30° C. or less; (ii) at least one hydrophilic thickener; (iii) at least one pigment; and (iv) water. The cosmetic composition according to the present invention can provide a good feeling during use and appropriate adhesiveness to fake eyelashes, and is stable over time.

Solvent-free method of encapsulating a hydrophobic active

Present disclosure relates to a solvent-free method of encapsulating a hydrophobic active in personal care, hydrophobic active in crop protection or a hydrophobic active pharmaceutical ingredient (API) in polymeric nanoparticles. The method includes mixing the hydrophobic active in a polymer melt, wherein the polymer melt comprises a melt of a block co-polymer, wherein the polymer melt acts as a solvent for the hydrophobic active. The method further includes maintaining the polymer melt in water for sufficient time to allow self-assembly of the block co-polymer to encapsulate the hydrophobic active therein.

Biotechnologically-produced cellulose-containing article for dermatological use
11529433 · 2022-12-20 · ·

A cellulose-containing article for treating an area of skin, wherein the article comprises BNC in an amount of at least 1% by weight and at most 15% by weight, comprises fluid in an amount of at least 85% by weight and at most 99% by weight, has an average thickness of at least 0.5 mm and at most 8 mm, wherein the BNC is of microbial origin.

Oil-in-water emulsion cosmetic
11529293 · 2022-12-20 · ·

A purpose of the present invention is to provide an oil-in-water emulsion cosmetic having a fresh feeling in use like that of a skin-care cosmetic such as a milky lotion, while also allowing titanium oxide or zinc oxide, which are ultraviolet scattering agents, to be stably blended into the oil phase, and also providing excellent sunscreen effects. The present invention relates to an oil-in-water emulsion cosmetic characterized by comprising (A) an ultraviolet scattering agent having a hydrophobic surface; (B) a water-soluble alkyl-substituted polysaccharide derivative; (C) a higher alcohol; and (D) a non-ionic surfactant. The emulsion cosmetic of the present invention preferably has a viscosity, measured by a B-type viscometer at 30° C., of 12,000 mPa.Math.s or lower.

Method of preparing silica nanocapsules and silica nanocapsules

There is provided a method of preparing silica nanocapsules, the method comprising mixing a surfactant with water at a temperature that is above the gel-to-liquid transition temperature of the surfactant to form a mixture, passing the mixture one or more times through at least one pore to obtain a dispersion of vesicles, and adding a silica precursor to the dispersion of vesicles to form silica nanocapsules. Also provided is a silica nanocapsule formed from a vesicle template, and a method of delivering one or more types of molecules to a subject. In a specific embodiment, hollow silica nanocapsules having substantially lens-shaped are synthesized by employing dimethyldioctadecylammonium bromide (DODAB) or dioctadecyldimethyl ammonium chloride (DODAC) as the vesicle template and tetraethyl orthosilicate (TEOS) as the silica precursor.

SUN CARE COMPOSITIONS WITH HOLLOW MESOPOROUS SILICA NANOSPHERES

Described herein are sun care compositions comprising at least one sunscreen active and hollow mesoporous silica nanospheres, and methods of making and using the sun care compositions. The presently described sun care compositions further comprise at least one of a cosmetically acceptable emollient, humectant, vitamin, moisturizer, conditioner, oil, silicone, suspending agent, surfactant, emulsifier, preservative, rheology modifier, pH adjustor, reducing agent, anti-oxidant, and/or foaming or de-foaming agent.

ANTIBACTERIAL DEODORANT COMPOSITION AND PRODUCTION METHOD THEREFOR
20220395439 · 2022-12-15 ·

The antibacterial deodorant composition according to the present invention includes an aqueous colloidal solution containing 1,500-2,500 ppm of nonionic copper nanoparticles having an average diameter (D50) of 2-10 nm.

Composite pigment and method for preparing the same

The present invention relates to a composite pigment comprising at least one small hollow core particle and optionally at least one large core particle wherein the surface of the small hollow core particle is at least in part covered with at least one coating layer comprising at least one inorganic solid UV filter, and the surface of the large core particle is optionally at least in part covered with at least one coating layer comprising at least one inorganic solid UV filter and/or at least one coloring pigment. The composite pigment according to the present invention can provide enhanced UV filtering effects and safety, and optionally enhanced coloring effects.

SUNSCREEN COMPOSITION WITH LOW STICKINESS
20220387281 · 2022-12-08 ·

The present invention relates to a topical preparation comprising a UV filter combination of certain microfine zinc oxide, 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI: Bis-Ethylhexyloxyphenol methoxyphenyl Triazine), 2-phenylbenzimidazole-5-sulfonic acid and/or one or more salts thereof and 2,4,6-tris[anilino(p-carbo-2′-ethyl-1′-hexyloxy)]-1,3,5-triazine (INCI: Ethylhexyl Triazone).