A61K2800/546

Ingestible formulations for transient, noninvasive reduction of gastric volume
09782348 · 2017-10-10 · ·

Provided are ingestible polymeric formulations and oral dosage forms for the reduction of gastric volume in the treatment of overweight and obese patients. The formulation includes an acid-sensitive, gelatin coating over a dehydrated hydrophilic polymer. When ingested, the acid-sensitive coating is quickly dissolved by gastric secretions and the hydrophilic polymer is exposed to the aqueous environment of the gastric milieu. The polymer absorbs water and expands to the point that will not allow the polymer to pass beyond the pyloric valve, and the expanded polymer is therefore trapped in the stomach.

PERSONAL CARE COMPOSITION AND USAGE METHOD THEREOF

It is an object of the present invention to provide a personal care composition having not only a low environmental impact and a good skin feel but also a high cleansing property. The object can be achieved by a personal care composition containing water and low substituted hydroxypropyl cellulose, wherein the low substituted hydroxypropyl cellulose has an average particle size (D.sub.50) on a volume basis by dry laser diffraction of 30 μm to 200 μm and an aspect ratio equal to or more than 1.0 and less than 5.0, and the like.

Water-soluble and/or water-swellable hybrid polymer

A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising: (a) from 90 mol-% to 99.9 mol-%, preferably 95 mol-% to 99.5 mol-% of repeating units according to Formula (1) ##STR00001## (b) from 0.01 mol-% to 10 mol-%, preferably to 5 mol-%, more preferably to 3 mol-% of crosslinking or branching units, wherein the crosslinking or branching units result from the incorporation of a monomer comprising at least two olefinically unsaturated double bonds;
wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.

Water-soluble and/or water-swellable hybrid polymer

A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising: (a) from 40 mol-% to 99.9 mol-% repeating units according to Formula (1) ##STR00001## (b) from 0.01 mol-% to 5 mol-% crosslinking or branching units, wherein the crosslinking or branching units result from the incorporation of a monomer comprising at least two olefinically unsaturated double bonds; (c) from 0.01 mol-% to 88.51 mol-% of neutral structural units; (d) from 1.98 mol-% to 20 mol-% of anionic structural units, wherein the repeating anionic structural units result from the incorporation of a monomer comprising at least one carboxylate anion, and wherein the repeating anionic structural units are different from units (a);
wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.

Oral care particles and system for the administration thereof

Disclosed is a system and method for the delivery, into interdental spaces, of oral care active agents contained in particles. The particles are made of one or more superabsorbent polymers (SAP), and are of size generally small enough to be easily applied into an interdental space. To this end, the particles typically have a length of below 1.5 mm. By virtue of the SAP's ability of absorbing several times its own weight in water, the particles will swell once in contact with saliva. As a result, the volume of the particles as applied in between teeth increases by at least eight times, thereby effectively making the particles larger than the average interdental gap size. The particles, once swollen, are thus held more firmly between the walls of the interdental space, thus preventing them from being easily washed away.

Cosmetic product in the form of a foam and make-up method

The invention relates to a foundation with a foam texture which is stable over time, comprising a silicone gel and an organomodified clay forming a three-dimensional network in a mixture of a large proportion of volatile oils.

N-vinyl lactam-based crosslinked polymer, cosmetic, absorbent agent for ink, and absorbent composite

The invention aims to provide a crosslinked polymer having excellent moisture retention properties, an excellent ethanol absorption capacity, excellent adhesiveness to the skin when applied to the skin as a cosmetic, and a high concentration of an effective component. The invention relates to a N-vinyl lactam-based crosslinked polymer including: a structural unit derived from a N-vinyl lactam; and a structural unit derived from a crosslinking agent, the N-vinyl lactam-based crosslinked polymer having an ethanol absorption capacity of 3 to 40 g per 1 g of the N-vinyl lactam-based crosslinked polymer, the N-vinyl lactam-based crosslinked polymer containing a particle having an aspect ratio determined by the following method of 1.15 to 10 in a proportion of 10% to 100% (by number) of the total number of the N-vinyl lactam-based crosslinked polymer and having a proportion of an extractable of 35 mass % or less in 100 mass % of the entire polymer, the method being “method of measuring aspect ratio” in which the aspect ratio is determined as a value obtained by measuring the major and minor axes of a primary particle of the N-vinyl lactam-based cross-linked polymer with an optical or electron microscope and dividing the major axis by the minor axis.

WATER-BASED COSMETIC
20210346270 · 2021-11-11 · ·

Provided is a water-based cosmetic that excels in adhesion, quick-drying property, spreadability without causing uneven application, and easiness of fine control of color density. A water-based cosmetic contains 2 to 18% by mass of a water-insoluble water absorbent polymer; 15 to 95% by mass of water; and 0.5 to 45% by mass of a powder, the water-based cosmetic having a penetration of 0.1 N or larger, where the penetration being hardness measured by using a pressure sensing shaft with a 10-mm-diameter spherical end, at a penetration speed of 6 cm/min, an insertion depth of 10 mm, and a temperature of 25° C.

COSMETIC PRODUCT

This cosmetic product has extensibility and imparts use feels such as silkiness and smoothness, and further demonstrates excellent soft focus effects, and contains: (A) spherical organopolysiloxane particles of which 90% by mole or more are constituted from organosilsesquioxane units and which have a volume average particle size of 0.1 to 30 μm and an average refractive index of 1.44 to 1.57, and; (B) an oil agent; and one or more selected from (C) a silicone crosslinked product and (D) a silicon resin coating silicon rubber powder.

N-vinyl lactam-based crosslinked polymer, cosmetic, absorbent agent for ink, and absorbent composite

The invention aims to provide a crosslinked polymer having an excellent liquid absorption capacity and sufficient gel-pulverizability. The invention relates to a N-vinyl lactam-based crosslinked polymer including: a structural unit derived from a N-vinyl lactam-based monomer; and a structural unit derived from triallyl cyanurate, the N-vinyl lactam-based crosslinked polymer containing the structural unit derived from triallyl cyanurate in a ratio of 0.12 to 0.48 mol % to 100 mol % of all structural units.