The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.

The present invention is directed to a hemostatic patch comprising a porous substrate and at least a pair of co-reactive polymer reagents comprising at least one nucleophilic polyalkylene oxide based component and at least one electrophilic polyalkylene oxide-based on the porous substrate in a molar ratio of about 0.2 to about 0.9:1 of primary nucleophilic groups in excess to available electrophilic groups. The present invention is also directed to processes for the manufacture and use of such hemostatic patches.

A forming apparatus for forming a plurality of apertures in a nonwoven substrate is provided. The apparatus includes intermeshing members having a first and second member. The first member includes a body portion and a plurality of conical-shaped pins. The plurality of conical-shaped pins each have a first section having a first wall extending from a base portion to a distal portion, at least a portion of the first wall disposed at a first angle greater than 17.5 degrees relative to a central axis. The plurality of conical-shaped pins each have a second section having a second wall extending from a base portion, the base portion extending from the first member body portion, at least a portion of the second wall disposed at a second angle relative to the central axis of each conical-shaped pin, the second angle being different than the first angle and less than 20 degrees.

A forming apparatus for forming a plurality of apertures in a nonwoven substrate is provided. The apparatus includes intermeshing members having a first and second member. The first member includes a body portion and a plurality of conical-shaped pins. The plurality of conical-shaped pins each have a first section having a first wall extending from a base portion to a distal portion, at least a portion of the first wall disposed at a first angle greater than 17.5 degrees relative to a central axis. The plurality of conical-shaped pins each have a second section having a second wall extending from a base portion, the base portion extending from the first member body portion, at least a portion of the second wall disposed at a second angle relative to the central axis of each conical-shaped pin, the second angle being different than the first angle and less than 20 degrees.

Organosilicon quaternary ammonium compounds, their formulations, including powdered and solid formulations, and methods of use to treat infections in humans and animals.

Organosilicon quaternary ammonium compounds, their formulations, including powdered and solid formulations, and methods of use to treat infections in humans and animals.

A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate.

A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate.

A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate.

Described is a fiber material having a substrate of non-ionic, non-woven fibers, and at least one additional component, which is an agent that comprises at least one group capable of forming a hydrogen bond, wherein the non-ionic, non-woven fibers are crosslinked by the agent. The fiber material can be of use in various fields, in particular household products, hygiene products and the like, these fiber materials are of particular use in wound treatment.