Provided herein is a scar dressing formulation comprising a blend of a high molecular weight silicone elastomer crosspolymer and a silicone oil, wherein said silicone elastomer crosspolymer is in a volatile fluid. The formulation has a soft, silky feel without being greasy and dries quickly to form a durable, flexible scar dressing.

Provided herein is a scar dressing formulation comprising a blend of a high molecular weight silicone elastomer crosspolymer and a silicone oil, wherein said silicone elastomer crosspolymer is in a volatile fluid. The formulation has a soft, silky feel without being greasy and dries quickly to form a durable, flexible scar dressing.

The invention provides a class of polymeric materials being ABA tri-block or AB di-block, comprised of biodegradable segments and poly(propylene oxide) (PPO) segment and uses thereof.

The invention provides a class of polymeric materials being ABA tri-block or AB di-block, comprised of biodegradable segments and poly(propylene oxide) (PPO) segment and uses thereof.

A wound dressing is provided. The wound dressing includes a moisture-transmissible backing layer having a first major surface, a second major surface, and a backing layer perimeter; an absorbent hydrophilic adhesive adhered to at least a portion of the second major surface of the backing layer, the absorbent hydrophilic adhesive comprising an absorbent hydrophilic adhesive perimeter; an antimicrobial agent disposed in the absorbent hydrophilic adhesive; a porous layer having a first side adhered to the absorbent hydrophilic adhesive, a second side, and a porous layer perimeter; and a second hydrophobic adhesive adhered to the second side of the porous layer. The second major surface has a first hydrophobic adhesive disposed thereon proximate the backing layer perimeter. 100% of the absorbent hydrophilic adhesive perimeter is overlapped by the backing layer. At least 50% of the porous layer perimeter is overlapped by the absorbent hydrophilic adhesive.

A wound dressing is provided. The wound dressing includes a moisture-transmissible backing layer having a first major surface, a second major surface, and a backing layer perimeter; an absorbent hydrophilic adhesive adhered to at least a portion of the second major surface of the backing layer, the absorbent hydrophilic adhesive comprising an absorbent hydrophilic adhesive perimeter; an antimicrobial agent disposed in the absorbent hydrophilic adhesive; a porous layer having a first side adhered to the absorbent hydrophilic adhesive, a second side, and a porous layer perimeter; and a second hydrophobic adhesive adhered to the second side of the porous layer. The second major surface has a first hydrophobic adhesive disposed thereon proximate the backing layer perimeter. 100% of the absorbent hydrophilic adhesive perimeter is overlapped by the backing layer. At least 50% of the porous layer perimeter is overlapped by the absorbent hydrophilic adhesive.

Disclosed herein are electrospun fibrous matrix and its production method. The method mainly includes the steps of, mixing a first polymer and a drug to form a first mixture, and sonicating the first mixture until a plurality of microparticles are formed with the drug encapsulated therein; and mixing the plurality of microparticles with a second polymer to form a second mixture, subjecting the second mixture to a wet electrospinning process to form the electrospun fibrous matrix. The thus-produced electrospun fibrous matrix is characterized by having a plurality of first and second fibrils woven together, in which each second fibril has a plurality of drug-encapsulated microparticles independently integrated and disposed along the longitudinal direction of the second fibril. Also encompassed in the present disclosure is a method for treating a wound of a subject. The method includes applying the present electrospun fibrous matrix to the wound of the subject to accelerate wound healing.

Disclosed herein are electrospun fibrous matrix and its production method. The method mainly includes the steps of, mixing a first polymer and a drug to form a first mixture, and sonicating the first mixture until a plurality of microparticles are formed with the drug encapsulated therein; and mixing the plurality of microparticles with a second polymer to form a second mixture, subjecting the second mixture to a wet electrospinning process to form the electrospun fibrous matrix. The thus-produced electrospun fibrous matrix is characterized by having a plurality of first and second fibrils woven together, in which each second fibril has a plurality of drug-encapsulated microparticles independently integrated and disposed along the longitudinal direction of the second fibril. Also encompassed in the present disclosure is a method for treating a wound of a subject. The method includes applying the present electrospun fibrous matrix to the wound of the subject to accelerate wound healing.

The present invention relates to a multilayer composite material for the treatment of wounds and lesions and to a dressing comprising said multilayer material.

The present invention relates to a multilayer composite material for the treatment of wounds and lesions and to a dressing comprising said multilayer material.