An article having anti-microbial effect is provided. The article includes an occlusive layer and a substrate having a nanostructured surface. The nanostructured surface is coated with a metal oxide layer and the metal oxide layer includes a metal oxide.

Disclosed is a biocomposite product with high microbial activity obtained by using bee bread, the method of obtaining this product and using of this biocomposite material for the coating of products like artificial materials, packaging, etc. to be used in areas requiring hygiene or their use as an intermediate raw material.

The present disclosure provides an anti-infective and anti-adhesive wound dressing based on nonspecific adhesion to bacteria, which includes a micron-sized porous membrane with polyolefin contained in its surface and does not contain any bactericide. According to the disclosure, through targeted selection of a material and surface structure of the porous membrane, nonspecific adhesion to the bacteria on the wound surface can be formed by good adaptability of its own surface energy and the structure of the porous membrane to surface energy of the bacteria, preventing the bacteria from penetrating into wound tissues and thus realizing the anti-infection for the bacteria and the anti-adhesion to the wound. Furthermore, no bactericide is required to be added, which not only reduces infection of the wound, but also weakens factors which are not conducive to wound healing, such as aggravation of inflammation caused by bacterial toxin released after bacterial rupture in traditional sterilization mechanisms.

The present disclosure provides an anti-infective and anti-adhesive wound dressing based on nonspecific adhesion to bacteria, which includes a micron-sized porous membrane with polyolefin contained in its surface and does not contain any bactericide. According to the disclosure, through targeted selection of a material and surface structure of the porous membrane, nonspecific adhesion to the bacteria on the wound surface can be formed by good adaptability of its own surface energy and the structure of the porous membrane to surface energy of the bacteria, preventing the bacteria from penetrating into wound tissues and thus realizing the anti-infection for the bacteria and the anti-adhesion to the wound. Furthermore, no bactericide is required to be added, which not only reduces infection of the wound, but also weakens factors which are not conducive to wound healing, such as aggravation of inflammation caused by bacterial toxin released after bacterial rupture in traditional sterilization mechanisms.

The present disclosure relates generally to wound inserts that may include an outer layer and an inner core of biopolymers that may be used in the therapy of tunneling wounds and for facilitating wound healing. Kits for use in practicing the methods are also provided.

The present invention provides a modified collagen comprising S-nitroso groups and a method of manufacture of such a modified collagen. Also provided is a wound dressing comprising such a modified collagen, particularly a wound dressing comprising a formulated composition comprising such a modified collagen.

The present invention provides a modified collagen comprising S-nitroso groups and a method of manufacture of such a modified collagen. Also provided is a wound dressing comprising such a modified collagen, particularly a wound dressing comprising a formulated composition comprising such a modified collagen.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided for treating biofilms without inducing antimicrobial resistance.

The present disclosure relates generally to wound dressing compositions and methods of manufacturing the wound dressing compositions of the present technology. The wound dressing composition includes a mixture of a collagen and/or chitosan and oxidized regenerated cellulose (ORC) with a layer of citric acid disposed therein. Also disclosed herein are methods of manufacturing such wound dressing compositions as well as kits including such wound dressing compositions.

The present disclosure provides wound dressing compositions that disrupt biofilm formation in a wound upon application. The wound dressing composition includes a first layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), and at least one bacteria reducing active ingredient and a second layer comprising a homogeneous mixture of a collagen, an oxidized regenerated cellulose (ORC), a silver compound, and at least one bacteria reducing active ingredient, and the uses thereof. Also disclosed herein are kits comprising the wound dressing compositions of the present technology, and instructions for use.