A preparation method of a hemostatic material is provided, wherein the method mainly includes mixing a keratin and an alginate; obtaining a keratin-alginate composite scaffold by a freeze-gelation method; and drying the keratin-alginate composite scaffold to obtain a hemostatic material. Further, a methylene blue can be loaded into the hemostatic material so that the hemostatic material has antimicrobial photodynamic abilities.

A solvatochromic indicator for detecting the presence of a bacterial infection is disclosed. An indicator consisting of Beta vulgaris and further optionally comprising Curcuma longa, isopropyl alcohol, and any combination thereof, undergoes a detectable color change in the presence of an infection. Further provided are filaments treated with the solvatochromic indicator wherein the detectable color change of the indicator is based on the pH of the tissues with a bacterial infection.

The present disclosure provides a dressing configured to cover a wound. The dressing includes a substrate layer, a contact layer and a readable pattern layer. The substrate layer is light-permeable. The contact layer is located at a side of the substrate layer, and the contact layer is configured to contact the wound or skin around the wound. The readable pattern layer is disposed on the contact layer. The readable pattern layer includes a plurality of positioning marks and a plurality of colored cells. The positioning marks are configured to define an information area. The colored cells are located in the information areas, wherein at least part of the colored cells includes a biological indicator, and the positioning marks and the colored cells are visible through the substrate layer.

A polymer composition comprising an organic polymer and a mica containing effect pigment, e.g., a pearlescent pigment comprising mica, well suited for producing molded articles, in particular, for molding articles comprising thin sections and or delicate features, such as a hollow interior defined by a thin wall or structural features susceptible to tear or other damage and the like, is provided as are a method for preparing molded articles comprising the polymer composition and articles comprising the polymer composition, including, for example, an article used to deliver a medical or personal care component such as a tampon applicator, and a method for preparing molded articles comprising the polymer composition. Optionally, articles of the present disclosure have a varying translucency or opacity about a dimension of the article.

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising:

hydrophilic monomer; and
indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer;
characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising:

hydrophilic monomer; and
indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer;
characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

To provide a composition for wet indicator excellent in discoloration performance. What is disclosed is a composition for wet indicator comprising an oily gel and a wet-sensitive colorant composition.

To provide a composition for wet indicator which is excellent in discoloration performance and is suppressed in odor. What is disclosed is a composition for wet indicator comprising: a hydrocarbon oil (A), at least one selected from saturated fatty acids having 16 or more carbon atoms and derivatives thereof (B), and a wet-sensitive colorant composition (C), wherein the component (B) is contained in an amount of 2 to 85 parts by mass based on 100 parts by mass of the total amount of the components (A) to (C).

The present disclosure relates generally to wound dressing compositions that detect nitric oxide production in a wound upon application. The wound dressing composition comprises a first layer comprising an absorbent layer, a second layer comprising a reaction pad, a third layer comprising a transparent backing film, and optionally a fourth layer comprising a wicking layer. In the wound dressing composition, the second layer comprises a reaction pad of a dried reaction mixture to detect the presence of nitric oxide in a wound. The wound dressing composition can be a visual indicator of the presence of nitric oxide in a wound; a visual indicator of the wounds healing status.

The present disclosure relates generally to wound dressing compositions that detect nitric oxide production in a wound upon application. The wound dressing composition comprises a first layer comprising an absorbent layer, a second layer comprising a reaction pad, a third layer comprising a transparent backing film, and optionally a fourth layer comprising a wicking layer. In the wound dressing composition, the second layer comprises a reaction pad of a dried reaction mixture to detect the presence of nitric oxide in a wound. The wound dressing composition can be a visual indicator of the presence of nitric oxide in a wound; a visual indicator of the wounds healing status.