A bioabsorbable medical device or a medical device component comprises an absorbable component prepared by subjecting a prefabricated component of an iron-based raw material to ion nitriding. Substance composition inside the absorbable component changes with the depth from the surface. The absorbable component comprises at least a first part and a second part. The first part surrounds the second part. Hardness of the first part is higher than hardness of the second part. An interface exists between the first part and the second part. A crack generated in the first part is impeded by the interface when extending to the second part. On the premise of ensuring radial stand strength, the bioabsorbable medical device or medical device component and a preparation method thereof reduce wall thickness of an iron-based stand, improve a stand corrosion rate and malleability, and achieve broader adaptability.

Methods of producing bioresorbable porous biocomposites for orthopaedic applications are provided. In an exemplary embodiment of a resorbable orthopaedic implant of the present disclosure, the implant comprises a porous alloy of at least a first metal and a second metal sintered together, the alloy configured to resorb into a body at substantially an atomic level without flaking off, wherein a porosity of the implant is defined by a first plurality of interconnected holes having a first range of sizes.

Example systems, methods, and apparatus are disclosed herein for functional polymer nanocomposites for stimuli-responsive Dynamic Ring to treat Cardiac Mitral Valve Disorder. The stimuli-responsive material may be a magnetically-induced shape memory nanoparticle such as Hematite dispersed in PLA. Such Hematite may be at a concentration of 10 wt % to 20 wt %. The Dynamic Ring may be produced by a process of additive manufacturing including the polymer nanocomposites in the vicinity of the patient.

A prosthetic valve comprising a conical shaped sheet structure and a support structure, the sheet structure having a closed distal end and a plurality of elongated ribbon members that are positioned proximate each other in a joined relationship, whereby the ribbon members form a plurality of fluid flow modulating regions that close when fluid flow through the valve exhibits a negative flow pressure and open when fluid flow through the valve exhibits a positive flow pressure, the support structure having at least one elongated cardiovascular structure engagement member that is associated with one of the ribbon members and adapted to engage a cardiovascular structure.

A spinal implant device has a synthetic or metallic or a combination thereof of these materials in an implant body structure and stem cells in a coating, or a sheet, wrap or a membrane wrap applied to surfaces on the implant body structure or alternatively filled with a plug of stem cell laden material. The implant body structure preferably has an aperture or channel. The spinal implant device may include anchoring holes to secure the device to the spinal skeletal structure with fasteners or alternatively can simply be held in place by and between adjacent vertebrae.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.

A prosthetic valve comprising a conical shaped sheet structure and a support structure, the sheet structure having a closed distal end and a plurality of elongated ribbon members that are positioned proximate each other in a joined relationship, whereby the ribbon members form a plurality of fluid flow modulating regions that close when fluid flow through the valve exhibits a negative flow pressure and open when fluid flow through the valve exhibits a positive flow pressure, the support structure having at least one elongated cardiovascular structure engagement member that is associated with one of the ribbon members and adapted to engage a cardiovascular structure.

The present invention is directed to a largely nickel-free iron alloy or a nickel-free stainless steel having the following composition: TABLE-US-00001 14.0% by wt.-16.5% by wt. chromium 10.0% by wt.-12.0% by wt. manganese 3.0% by wt.-4.00% by wt. molybdenum 0.55% by wt.-0.70% by wt. nitrogen 0.10% by wt.-0.20% by wt. carbon 0.00% by wt.-2.00% by wt. impurities, such as other metals, semimetals, metal salts and/or non-metals the rest up to 100% by wt. is iron,
which is in particular suitable for the production of stents as well as to stents made of this alloy.