The invention relates to a method and a device for producing an implant, wherein a natural bone microstructure of a natural bone region is detected (S1), an implant region in the natural bone region is marked (S2), the detected bone microstructure in the marked implant region is analysed to determine reproduction parameters (S3), and on the basis of the determined reproduction parameters, an artificial microstructure for producing the implant is created (S4).

The present invention relates in part to a hydrogel composition and a method of fabricating the hydrogel composition comprising the steps of providing a solution comprising a polymer comprising crosslinkable groups; providing a solution comprising a crosslinking agent; mixing the solution comprising a polymer comprising crosslinkable groups and the solution comprising the crosslinking agent to form a combined solution; and crosslinking the combined solution. The invention also relates in part to a methods of treatment using the hydrogel composition.

The present invention relates to methods of photocatalyzed bonding of compounds directly to surface metal oxides and the articles obtained therefrom. The methods for preparing an article having a compound bonded to a metal oxide comprise applying a compound that includes a photograftable moiety to the surface of the article; and applying light to the compound.

It has been discovered that iron-platinum ferromagnetic particles can be dispersed in a polymer and coated into or onto, or directly linked to or embedded on to, medical devices and magnetized. The magnetized devices are used to attract, capture, and/or retain magnetically labeled cells on the surface of the device in vivo. The magnetic particles have an iron/platinum core. Annealing the Fe/Pt particle is very important for introducing a L10 interior crystalline phase. The Fe:Pt molar ratio for creation of the crystal phase is important and a molar range of 1.2-3.0 Fe to Pt (molar precursors, i.e. starting compounds) is desired for magnetization. The magnetic force as a whole can be measured with a “Super Conducting Quantum Interference Device”, which is a sensitive magnetometer. The overall magnetic force is in the range from 0.1 to 2.0 Tesla.

A bionic arm comprises a bionic palm and at least one finger. The at least one finger comprises a nanofiber actuator. A nanofiber actuator comprises a composite structure and a vanadium dioxide layer. The composite structure comprises a carbon nanotube wire and an aluminum oxide layer. The aluminum oxide layer is coated on a surface of the carbon nanotube wire, and the aluminum oxide layer and the carbon nanotube wire are located coaxially with each other. The vanadium dioxide layer is coated on a surface of the composite structure, and the vanadium dioxide layer and the composite structure are located non-coaxially with each other.

The present disclosure is concerned with magneto-patterned cell-laden hydrogel materials and methods of making and using those materials. The disclosed materials are useful for, among other things, repair of tissue defects, e.g., tissue at a tissue interface such as a bone-cartilage interface.

The present invention relates to a macroscopically alignable, injectable, soft hydrogel composition which is able to form an anisotropic structure in vivo, after injection, to generate healthy functioning tissue and regenerate injured or diseased soft tissue.

The present invention relates to a macroscopically alignable, injectable, soft hydrogel composition which is able to form an anisotropic structure in vivo, after injection, to generate healthy functioning tissue and regenerate injured or diseased soft tissue.

A low profile implant, system and method of deployment includes a frame comprising an elongate body having ends that overlap to form an annular configuration of the frame. A circumference of the frame may be modified by varying an extent of the overlap between the ends of the elongate body. The elongate structure may extend through a sleeve of a number of respective anchor housings of the implant along a first axis, and anchors may be deployed through bores in the anchor housings along a second axis to secure the anchor housings to tissue. The implant may be deployed about and anchored to a valve annulus, and the circumference of the frame, and associated anchored tissue, may be adjusted to reconfigure the valve annulus.

A dental implant and a method of dental restoration. In one embodiment, the dental implant includes at least one root adapted to be inserted into a hole of a mandibular bone or a maxillary bone, and an abutment on top of the root adapted to mate with a crown. Each root may be a lattice scaffold configured to house bone grafting material. A bone grafting material may be inserted within the lattice scaffold to occupy vacant space within the root and the hole of the mandible/maxilla. A method of dental restoration may include obtaining an image of at least a portion of a mandibular bone or a maxillary bone of a patient, drilling a hole into the mandibular bone or maxillary bone, inserting a one-piece dental implant with an abutment and one or more non-threaded roots into the hole, and installing a crown on the abutment of the one-piece dental implant.