Implementations described herein provide for junctionless monolithic composite implants and methods for manufacturing the same. The implant includes a monolithic composite body having a first region comprising a first metal alloy, a second region comprising a second metal alloy, and a transition region disposed between the first region and the second region formed from a bonded mixture of the first alloy and the second alloy. In one example, the transition region is a sintered mixture of the first alloy and the second alloy. In another example, the transition region is disposed at a region of minimum stress within the monolithic composite body under physiological loading conditions of the implant.

The device is intended for the noninvasive induction of dynamic deformation of body tissue to differentiate tissue cells. It comprises the following components: (i) a suspension of particles suspended in solution; and (ii) an external actuator which is capable of magnetically, electrically, vibrationally, or thermally stimulating the suspended particles.

The present invention relates to an implant (10) comprising an implant body having a first surface area (A1, A2, A3, A4) configured for contact with soft connective tissue and a second surface area configured for contact with bone tissue, wherein the first surface area is covered with a coating comprising tantalum and the second surface area is formed by a material, which is different than the one forming the coating.

A device and method for manufacturing artificial solid bone by metal 3D printing technology comprises: a metal 3D printing technology is used and preferably with CoCr alloy and laser sintering to form a solid bone with a specific change in shape and density; a synchronous cutting operation performed on approximately 80% of the preferred surface of the solid bone while the metal 3D printer unit is printing the solid bone, to make the solid bone have the following surface roughness: Ry<12 m or less; and a synchronous polishing operation performed on at least one joint surface of the solid bone, to make the joint surface have the following surface roughness: Class A4=Ra0.063 m or less.

The present invention relates to an implant comprising an implant body having a first surface area configured for contact with soft connective tissue and a second surface area configured for contact with bone tissue, wherein the first surface area is covered with a coating comprising tantalum and the second surface area is formed by a material, which is different than the one forming the coating.

A second generation, version III prosthetic joint for replacing a metatarsophalangeal joint of a human foot has a metatarsal head component with a convex bearing surface that rotates, inverts and everts, and slightly abducts and adducts; normal movement of a healthy human great toe joint, against the concave surface of the phalangeal base second component. The base is elliptical and formed by two different radii of curvature with a desired ratio and constructed of high density medical grade polyethylene. The internal surface is titanium alloy with an intentionally irregular roughened surface for increased bone attraction and increased surface tension. The stem is a shortened square alloy peg. also roughened. The metatarsal head component has an internal surface for confronting the bone with a four chamfer flat surface configuration, one surface is horizontal and parallel to the long axis of the metatarsal bone, another extends approximately perpendicular thereto, and two others extend at angles to the long axis. All of these surfaces are irregularly roughened titanium alloy. Extending from the perpendicular surface, are two parallel short cylindrical pegs. These pegs aid in early security to the bone, assist the resistance of angular displacement, and increase the surface contact area with bone. The horizontal lower surface allows better distribution of vertical forces and helps resist separation of the metatarsal implant from the bone. The thinned metatarsal component articular surface has four different regions formed by four different radii of curvature with desired ratios to one another. These four surfaces allow the head and base components to reproduce pivoting of a healthy toe joint. A dedicated method for installing the prosthetic joint with improved accuracy is part of this invention.

There are instruments dedicated to this implant prosthesis that allow for proper alignment and ease of installation even to the relatively inexperienced surgeon providing that the use of said instrumentation has been taught by skilled instructors and proctored to insure understanding of the instrumentation and procedure. The first of such instruments allows for alignment of the guide in the proper plane of the foot. This all-important guide is a first of its kind for this Great foe Joint surgery. From the placement of this guide, all other guides and steps can be accurately placed to insure exactitude and reproducibility. Onto this instrument is added the first of such guides to reduce the subject bone to the dimensions and configuration for implantation. A second guide is then added to the first guide to allow for the preparation of the apposing surface of the

An ossicular prosthesis has a head plate as a first fastening element, a second fastening element for the mechanical connection to the ossicular chain, or to the inner ear, and a connecting element. The head plate has a central coupling region and radially outward extending bridging elements which are connected to the coupling region via a radially inner end region and each transition into an outer free end section. The bridging elements are connected to the coupling region so that they fold together upon introduction of a force component parallel to the longitudinal axis, wherein their end sections are pivoted radially closer to the longitudinal axis and thereby also execute an axial movement. The bridging elements, without this force, extend from the coupling region at a predefined, fixed angle. The prosthesis can be inserted into the middle ear of the patient more easily and through a much smaller artificial opening.

Joint resurfacing and/or replacement devices, systems and methods that include thin film ternary ceramic coatings that are effective to provide reliable articulation and bearing surfaces and protection of both articular and modular junction surfaces from the potential for corrosion, wear, and fretting, and reduce the potential for release of metal ions from the joint systems. Isoelasticity is provided according to the particular joint resurfacing/replacement devices, systems and methods based on parameters that include material of construction, porosity and coating system. The thin film ternary ceramic coatings may be functionalized to enhance hydrophilicity and may be employed in any anatomical articulating joint region. Titanium alloy composite structures are provided that include an ultra-porous structured titanium alloy bone fixation surface and an opposed solid articular surface and a thin film ternary ceramic coating applied to one or both opposed surfaces.

Cobalt in oxidized state for use as anti-artifact layer (4) covering a metallic substrate (1) of a medical device for reducing the production of artifacts in MRI caused by the magnetic property of the (1), wherein the anti-artifact layer (4) is present at outermost surface of the metallic substrate (1) and has at least 30% of cobalt ratio (at % Co) to the total amount of transition metallic atoms present therein, and at least 90% of cobalt atoms present within the anti-artifact layer (4) are converted into at least one of Co(II) oxidized state and Co(III) oxidized state.

A medical device that is at least partially coated with an enhancement layer, and a method for inserting the medical device a patient. One non-limiting type of enhancement layer that can be used includes titanium oxynitride or titanium nitride oxide (TiNOx) and/or zirconium oxynitride (ZrNxOy).