The present invention concerns a polyelectrolyte coating comprising at least one polycationic layer consisting of at least one polycation consisting of n repetitive units having the formula (1) and at least one polyanionic layer consisting of hyaluronic acid. The polyelectrolyte coating has a biocidal activity and the invention thus further refers to the use of said polyelectrolyte coating for producing a device, in particular a bacteriostatic medical device, more particularly an implantable device, comprising said polyelectrolyte coating, and a method for preparing said device and a kit.

Antiseptic compositions comprising at least one salt of EDTA are disclosed. These compositions have broad spectrum antimicrobial and antifungal activity and they also have anticoagulant properties. The antiseptic compositions have also demonstrated activity in penetrating and breaking down microbial slime, or biofilms. They are safe for human and medical uses and may be used as prophylactic preparations to prevent infection, or to reduce the proliferation of and/or eliminate existing or established infections.

Intraperitoneal administration of glutamine to reduce adhesions in the peritoneum of a patient.

The present invention addresses the problem of providing a means for treating pain in the hands or feet, which can be performed in a safer manner and works by embolizing abnormal capillary vessels. The present invention provides a treatment agent for pain in the hands or feet, wherein: the pain treatment agent contains a particulate embolic material having an average particle size of 10 to 200 ?m; the pain treatment agent is employed by being injected into an artery in a hand or a foot; and the administration of the pain treatment agent is completed on the basis of confirmation of at least one predetermined phenomenon.

A composition including: (a) one or more alkyl acrylaor alkyl methacrylate based polymer film forming agents; (b) one or more (C.sub.1-C.sub.6)alkyl N(alpha)-(C.sub.10-C.sub.25)alkanoyl-L-arginate disinfectant or a salt thereof; (c) a solvent system comprising: (c1) one or more water immiscible solvents selected from (C.sub.1-C.sub.5)alkyl-COO(C.sub.1-C.sub.6)alkyl, ((C.sub.1-C.sub.6)alkyl).sub.3SiO-Si((C.sub.1-C.sub.6)alkyl).sub.3, (C.sub.1-C.sub.5)alkyl-O(C.sub.2-C.sub.5)alkyl and a mixture thereof; (c2) acetone; and (c3) one or more (C.sub.2-C.sub.3) alcohols and processes for its preparation. An adherent film, including: (a) one or more film forming agents; and (b) one or more disinfectants; and processes for its preparation.

The present invention relates to a mattress for preventing and treating bedsores comprising a main body (1) and an exchangeable element (2, 3, 4), said exchangeable element (2, 3, 4) comprising an absorbent composition (7) and a disinfectant composition (8).

The present invention also relates to a method for manufacturing such a mattress, and comprising the following steps: production of the main body (1), covered with a cover (5), in particular in plasticized jersey, with a housing for at least one exchangeable element (2, 3, 4), production of an exchangeable element (2, 3, 4) in honeycomb cardboard or viscoelastic cellular foam, deposition of an absorbent composition (7) in the exchangeable element, deposition of a disinfectant composition (8) on the absorbent composition, arrangement of an envelope (11) around the exchangeable element (2, 3, 4), made in particular of a permeable nonwoven textile, placement of the exchangeable element (2, 3, 4) in the car responding housing of the main body (1).

An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate and a hemostatic agent. The substrate includes a first piece and a second piece that is joined with the first piece. The first piece includes the hemostatic agent and the second piece includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.

To reduce problems associated with clotting and thrombus formation, it is now common to lock intravascular access catheters between successive uses. Locking typically involves first flushing the catheter with saline to remove blood and other substances from the catheter lumen. After the catheter has been flushed, an anti-coagulant solution is injected to displace the saline and fill the lumen. Use of an effective antimicrobial substance along with anticoagulant during the same process is important to reduce the possibility of bacterial contamination and subsequent infection. The present invention deals with a safe, effective and economical catheter lock flush solution with excellent antimicrobial and anticoagulant activity. The unique ratio of the active components of the catheter lock solution used in the invention i.e. Sodium salt(s) of EDTA, Ethanol and D-mannitol with a suitable pH ensures broad-spectrum antimicrobial and optimum anticoagulant activity.

The invention relates to a functional wound dressing being able to detect and indicate the state of the wound, in particular with regard to infections for example caused by toxins produced by bacteria such Staphylococcus aureus and Pseudomonas aeruginosa. The present wound dressing can be used in moist wound healing and contains a substance being able to absorb wound exudate from the wound and to provide moisture to the wound.

A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.