A blood component separation device includes a centrifuge bowl for separating a blood component from blood, a plasma bag for storing a plasma component, a platelet intermediate bag for storing high-concentration platelet liquid having high-concentration of platelets, and a temporary storage bag (also used as a buffy coat bag) for storing low-concentration platelet liquid having low-concentration of platelets. The blood component separation device performs control, from the second cycle onward, to mix the low-concentration platelet liquid stored in the temporary storage bag in the immediately preceding cycle with whole blood to supply the mixed liquid to the centrifuge bowl. An amount of high-concentration platelet liquid to be collected in the platelet intermediate bag in the first cycle is set to be smallest among all cycles, and an amount of high-concentration platelet liquid to be collected in a last cycle is set to be greatest among all the cycles.

A biological component separation device includes a device main body which is formed of a soft material in a sheet-like shape and in which a filter accommodating unit is provided, a filter member, an introduction port member, and a lead-out port member. An introduction line and a lead-out line are provided in the device main body. In a state in which the device main body is suspended by an introduction tube, a filter accommodating unit inlet where the filter accommodating unit and the introduction line are connected is positioned lower than a filter accommodating unit outlet where the filter accommodating unit and the lead-out line are connected.

A blood bag system is provided with a liquid drug bag having an internal storage space in which a liquid drug is stored, and a third tube that is connected to the liquid drug bag and has a flow path therein connected to the storage space. A retention mechanism for separably retaining the liquid drug bag and the third tube is provided between the outer surface of the liquid drug bag and the outer peripheral surface of the third tube. The third tube can thus be inserted together with the liquid drug bag when the liquid drug bag is accommodated in a liquid drug bag pocket of a centrifugal transport device.

A blood filtration device comprising a generally cylindrical housing having an interior wall. An interior member is mounted interior of the housing and comprises an outer surface having a porous membrane disposed thereon. The housing and interior member are relatively rotatable and define an annular gap therebetween. The blood filtration device also comprises an inlet for directing fluid into the annular gap, a first outlet for exiting filtrate passing through the membrane, and a second outlet for directing from the annular gap the remaining retentate. The porous membrane comprises a first layer and a second layer.

Provided are a blood bag system and a blood treatment method capable of securely and efficiently obtaining a medium specific gravity blood component having a sufficiently low content rate of a light specific gravity blood component. In a blood bag system (10) used for a blood treatment method, in a transfer completed state in which whole blood in a first bag (12) is centrifuged to transfer blood plasma to a second bag (14) through a first transfer tube (24) and transfer red cell concentrates to a third bag (16) through a second transfer tube (26), a buffy coat is left in the first bag (12). In the transfer completed state, when a platelet added solution is transferred from a fourth bag (18) to the first bag (12) on which a centrifugal force acts through a third transfer tube (28), blood plasma in the buffy coat is discharged from the first bag (12).

A method is provided for controlling fluid flow through a tubing segment is provided in which a pump draws fluid through the tubing segment using negative pressure P. The method includes the steps of: a) operating the pump at an initial commanded fluid flow rate to draw fluid through the tubing segment; b) measuring on a continuous basis the P in the tubing segment; c) determining into which of four zones the measured P falls, a first zone being where P>X.sub.1, a second zone being where X.sub.1>P>X.sub.2, a third zone where X.sub.2>P>X.sub.3, and a fourth zone where X.sub.3>P; d) if P is in the first zone for greater than a first pre-established time period, then increasing the commanded flow rate of the pump and returning to step b); e) if P is in the second zone, then continuing to operate the pump at the flow rate at which the pump is currently operated and returning to step b); f) if P is in the third zone, for greater than a second pre-established time period, then decreasing the commanded flow rate of the pump and returning to step b); and g) if P is in the fourth zone, then commanding the pump to stop. A system including a programmable controller configured to automatically perform the method is also disclosed

Methods and container systems for processing biological fluids are disclosed. The container systems include an inner container within an outer container. The inner container wall is made of a porous material of a selected porosity that allows certain components to pass through said porous wall but retains other components. A treating solution is introduced into the chamber of the outer container.

The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

A flow path is formed in a cassette body of a blood component collection cassette. The cassette body includes a bulging structure in which at least a portion of the flow path is formed. A first gripped member, which is configured to be gripped by a first gripping member provided on a centrifugal separation device, is disposed on one surface of the bulging structure in a thickness direction thereof. A second gripped member, which is configured to be gripped by a second gripping member to which a load detection unit that is provided on the centrifugal separation device is fixed, is disposed on another surface of the bulging structure in the thickness direction thereof.

A kit for reduction of blood components in a blood-related medium (12) is disclosed, wherein it comprises a gel bead container (1) containing gel beads (2) and provided with an outlet tube (3), a drip chamber (4) provided with an inlet tube (5) and an outlet tube (6), a collection container (10) provided with an inlet tube (11), and a medium container (13) adapted to contain a blood-related medium (12) and provided with an outlet tube (15), wherein the outlet tube (3) of the gel bead container (1) is connectable with the inlet tube (5) of the drip chamber (4) via a sterile connecting device, wherein the outlet tube (6) of the drip chamber is connectable with the inlet tube (11) of the collection container (10) via a sterile connecting device, and wherein the outlet tube (15) of the medium container (13) is connectable to the inlet tube (5) of the drip chamber (4) via a sterile connecting device, as well as a method for reduction of blood components in a blood-related medium (12) by use of said kit.