There is provided an introducer system for percutaneously delivering a first and a second medical device to a patient. The system may comprise an introducer sheath having a longitudinal axis and a lumen formed therein. The system may also comprise a bifurcated hub coupled to a proximal end of the sheath. The hub may comprise a first arm having a first lumen and a first hemostasis valve for the passage of the first medical device. The hub may also comprise a second arm coupled to the first arm and having a second lumen and a second hemostasis valve for the passage of the second medical device. Further, the hub may comprise a connection port such that the first lumen and the second lumen are in communication with the lumen of the introducer sheath for the passage of at least one of the first and second medical devices through the introducer sheath for delivery to the patient.

An oxygenation device for use in connection with extracorporeal blood circulation, the device including a stacked oxygenator housing defining a blood inlet, a blood outlet and a blood flow path between the blood inlet and the blood outlet. The device further includes a plurality of stacked hollow fibers disposed inside the housing and along the blood flow path, the hollow fibers fluidly coupled to a gas inlet port and a gas outlet port. The blood inlet port has a blood inlet lumen fluidly coupled to the blood inlet and includes an inlet housing in fluid communication with the blood inlet lumen, the inlet housing adapted to house an inlet pressure sensor. The blood outlet port has a blood outlet lumen fluidly coupled to the blood outlet and includes an outlet housing in fluid communication with the blood outlet lumen, the outlet housing adapted to house an outlet pressure sensor.

The present invention relates to a gas exchange unit for use in extracorporeal membrane oxygenation (ECMO) or extracorporeal live support (ECLS) according to a method for producing such a gas exchange unit as well as a kit with a gas exchange unit and a humidifying and heating device.

A blood oxygenator includes a housing having a first end opposite a second end with a sidewall extending between the first end and the second end along a longitudinal axis. The housing defines an interior chamber having a liquid inlet at the first end and a liquid outlet at the second end. The oxygenator further includes a gas exchange assembly positioned within the interior chamber. The gas exchange assembly includes a retainer having an upper cap spaced apart from a lower cap by one or more spacers, and a gas exchange medium disposed between the upper cap and the lower cap. The gas exchange medium has a plurality of subunits stacked on top of each other, with each subunit having a plurality of layers of hollow fiber mats.

A system configured to enclose a premature fetus within an extracorporeal environment to promote growth of the fetus and increase viability of the fetus, The system includes a chamber having an interior space configured to enclose the fetus, a first fluid circuit that delivers sterile fluid to the chamber, and a second fluid system that transfers oxygen to the fetus. The system chamber includes a stop mechanism including a clamp and an actuator, the clanip positioned in the interior space, the actuator coupled to the clamp such that movement of the actuator moves the clamp, and the actuator positioned at least partially outside the interior space. A method of using the system to treat hyperbilirubinemia is also provided.

A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).

A blood processing unit for use in connection with extracorporeal blood circulation includes a housing including a blood inlet, an upper end cap defining a central inlet opening, and a blood outlet. Blood flows along a blood flow path between the blood inlet and the blood outlet. A plurality of layers of hollow fibers are disposed inside the housing and along the blood flow path. The hollow fibers are fluidly coupled to a gas inlet port and a gas outlet port. The device includes a flow distribution structure for modifying blood flowing along the blood flow path. The structure includes a body having a distal end, a proximal end, and an outer surface extending between the distal end and the proximal end. An inlet configured for connecting with the upper end cap is spaced from the proximal end. A plurality of curved dividers extend between the inlet and the body.

Certain embodiments of the invention are directed to methods of adjusting the concentration of one or more electrolytes in a patient's blood using a counter current electrolyte solution.

The present disclosure relates to a casting device for producing a potting for a gas exchanger and a method for producing such a potting. Accordingly, a casting device is proposed for producing a potting for a gas exchanger under the influence of a centrifugal force, comprising a distributor comprising an opening and at least one continuous channel and adapted to receive a fluid potting material via the opening and to guide it via the at least one channel. The casting device further comprises a cassette defining an inner cavity for receiving gas exchanger elements and which is fluidly connected to the at least one channel. The distributor comprises at least two distributor components which, in the assembled state of the distributor, define the opening, are connected to one another in a leak-proof manner, and form the at least one channel between adjacent regions.

The invention relates to a system for determining a cardiovascular parameter in a patient, wherein the system is adapted to work in conjunction with an extracorporeal blood treatment device (ECBTD) connectable to a patient's vascular system, wherein the ECBTD comprises a first circuit, the system comprising: a liquid-filled, second circuit thermally connected to the first circuit of the ECBTD via a heat exchanger, temperature changing means for generating a temperature change in the second circuit, temperature sensors TS2up and TS2down arranged in the second circuit upstream and downstream of the heat exchanger, respectively. A computer system connected to the temperature sensors and the temperature changing means is adapted to induce a temperature bolus within the first circuit of the ECBTD via the temperature changing means. From the individual temperature recorded as a function of time, temperature curves T2up(t) and T2down(t) are derived and evaluated.